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Anche se gli ultimi anni hanno visto uno sviluppo tumultuoso della ricerca oncologica, i tumori restano la causa di morte del 30% degli italiani. Gli avanzamenti terapeutici facilitano la guarigione e prolungano la vita, ma proprio per questo rendono più evidenti gli effetti indesiderati delle terapie e complicazioni delle neoplasie prima meno frequenti; in molti casi il danno da trattamento, piuttosto che quello dovuto alla neoplasia primitiva, diventa il principale azzardo per la qualità della vita e la sopravvivenza dei pazienti. Questo volume, insieme necessario e nuovo nel panorama della letteratura medica italiana, ne prende atto e presenta una revisione aggiornata e completa delle patologie del sistema nervoso centrale e periferico associate ai tumori e al loro trattamento. Scopo del volume è di presentare un approccio integrato tra specialisti che deve vedere il neurologo e l’oncologo in dialogo, e in grado di sviluppare una nuova capacità clinica super-specialistica la neuro-oncologia . Molti sono gli esperti che hanno contribuito alla sua preparazione mettendo in comune conoscenze su temi che variano dalle complicazioni metastatiche, a quelle della terapia chirurgica dei tumori, della radio- e chemio-terapia, alle sindromi paraneoplastiche, alla terapia del dolore, al delirium e alle alterazioni affettive associate alla malattia. Il libro si rivolge in particolare a neurologi, oncologi, palliativisti e chirurghi, ma è certamente utile ai medici di medicina generale e a tutti gli operatori che sono quotidianamente coinvolti nell’impegnativa opera di prendersi cura dei pazienti oncologici. .
Nervous system --- Neurology. --- Central nervous system --- Oncology. --- Tumors. --- Diseases --- Complications. --- Tumors --- Medicine --- Neuropsychiatry --- Oncology . --- Neurosurgery. --- Nerves --- Neurosurgery --- Surgery --- Neurology .
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Ein Rezeptbuch der besonderen Art für die neurologische und neurochirurgische Intensivmedizin: - Anleitung für alle Neueinsteiger, - Grundlage für das Qualitätsmanagement, - Muster für das eigene, klinikinterne Handbuch, - für eine sichere Patientenversorgung. Das Handbuch Intensivmedizin des Neurozentrums Heidelberg richtet sich an alle Ärzte und Pflegende - für schnelle Antworten auf Fragen im Klinikalltag.
Critical care medicine. --- Neurosurgery. --- Neurology . --- Intensive / Critical Care Medicine. --- Neurology. --- Nervous system --- Surgery.
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Erythropoietin and the Nervous System is the first book of its kind to bring together researchers from many different disciplines of neuroscience to present a current state-of-the-art review of multiple aspects of erythropoietin research as it relates to the nervous system. Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body. In addition to its traditional role as a hormone that stimulates red blood cell production, in recent years many laboratories have shown that EPO can act as a neuroprotective compound in a variety of injury paradigms in the nervous system. Past experience with the relatively safety profile of this FDA-approved drug makes it an ideal candidate to take into clinical trials for neuroprotection. We are on the verge of major clinical trials using this drug for neuroprotection in diseases ranging from stroke, to transverse myelitis to chemotherapy-induced peripheral neuropathy. This book should stimulate new research on erythropoietin and the nervous system and bring new investigators to the field. It will benefit scientists and clinicians interested in neuroprotection in the broadest sense.
Erythropoietin --- Physiological aspects. --- Colony-stimulating factors (Physiology) --- Hematopoietic growth factors --- Neurology. --- Neurosciences. --- Psychiatry. --- Neurosurgery. --- Nerves --- Neurosurgery --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Medicine --- Neuropsychiatry --- Surgery --- Diseases --- Neurology .
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Diagnosis and treatment modalities for neuro-oncologic diseases have made considerable advances in recent years. There is hardly a segment of the field of solid tumours that is experiencing such dynamic development with regard to basic scientific findings and clinical results. In the present book the world's leading experts have compiled the current practice-relevant knowledge of neuro-oncologic deseases. The book's clear structure and the uniform presentation of all chapters make this volume a valuable reference, especially for practice-oriented activities, allowing swift access to information about current treatment standards. Hence it will be of great value to both clinicians and researchers.
Central nervous system --- Tumors --- Treatment. --- Cancer --- Nervous system, Central --- Nervous system --- Oncology . --- Neurology. --- Neurosurgery. --- Surgical oncology. --- Oncology. --- Surgical Oncology. --- Medicine --- Neuropsychiatry --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Nerves --- Neurosurgery --- Diseases --- Excision --- Treatment --- Surgery --- Neurology .
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Ossification of the posterior longitudinal ligament (OPLL) is a hyperostotic condition of the spine with severe neurological deficits. In 1975 the Investigation Committee for OPLL, under the auspices of the Japanese Ministry of Health and Welfare, established diagnostic criteria for the condition, and with growing awareness of OPLL among Japanese researchers and spinal surgeons, the number of patients diagnosed with the condition in Japan has increased in recent years. As knowledge of OPLL has spread, there has also been an increase in the number of reported cases of the condition in other parts of the world: Asia, the United States, and Europe. Until now, however, little has been published on the subject in English; thus the appearance of this present volume is most timely. It brings together information on all aspects of OPLL - epidemiology, etiology, diagnosis, and treatment - with contributions by Japanese researchers and surgeons, including members of the Ministry of Health and Welfare Investigation Committee, and by American surgeons with expertise in the field. This collection of reports on OPLL, amply augmented with illustrations, will be of special interest to orthopedic surgeons and neurosurgeons, and to neurologists, rheumatologists, neuroradiologists, and pathologists.
Posterior longitudinal ligament --- Ossification. --- Diseases. --- Ossification --- Spine --- Diseases --- Orthopedics. --- Orthopedic surgery. --- Neurosurgery. --- Rheumatology. --- Surgical Orthopedics. --- Internal medicine --- Connective tissues --- Joints --- Nerves --- Neurosurgery --- Operative orthopedics --- Orthopedics --- Surgery, Operative --- Orthopaedics --- Orthopedia --- Surgery
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Part of the series sponsored by the European Association of Neurosurgical Societies. The Advances section presents fields of neurosurgery and related areas. The Technical Standards section features detailed descriptions of standard procedures to assist young neurosurgeons in their post-graduate training.
Nervous system --- Surgery. --- Nerves --- Neurosurgery --- Surgery --- Neurosurgery. --- Neurology. --- Radiology, Medical. --- Neurosciences. --- Neuroradiology. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Medicine --- Neuropsychiatry --- Diseases --- Neurology . --- Neuroradiography --- Neuroradiology
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History of medicine --- History of medicine --- Oncology. --- Radiology incl. echography, cat-scanning, nmr, pet-scanning. --- Surgery --- North America. --- Neurosurgery.
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Das vorliegende Buch ist ein in interdisziplinärer Zusammenarbeit zwischen Radiologen, Orthopäden, Unfallchirurgen und Neurochirurgen erstellter klinisch orientierter MRT-Bildatlas. Die aus Sicht der beteiligten Fächer wesentlichen Erkrankungen und Verletzungen der Wirbelsäule werden dargestellt. Neben einem umfangreichen Bildmaterial werden Hinweise zur Anatomie und Pathophysiologie, zu den MRT-Zeichen physiologischer und pathologischer Befunde, zu diagnostischen Fallstricken und zur klinischen Wertigkeit der Befunde gegeben. Durch die gleichzeitige Darstellung von Klinik und MRT-Diagnostik soll das Einarbeiten in eine eigenständige Bildbeurteilung der Wirbelsäule erleichtert werden. Die MRT hat zweifellos die Diagnostik im Bereich der Wirbelsäule revolutioniert; gerade an der Wirbelsäule stellen sich aber häufig diagnostische Fragen, die allein durch bildgebende Verfahren, auch durch die MRT, ohne Kenntnis des klinischen Befundes nicht beantwortet werden können. Das Buch ist in insgesamt sieben Buchteile mit 66 Kapiteln gegliedert, welche alle den gleichen formalen Aufbau aufweisen; dadurch wird eine rasche Orientierung auch bei speziellen Fragestellungen möglich.
Radiology. --- Neurosurgery. --- Orthopedics. --- Pediatric surgery. --- Traumatology. --- Imaging / Radiology. --- Surgical Orthopedics. --- Pediatric Surgery. --- Traumatic Surgery. --- Orthopedic surgery. --- Nervous system --- Surgery.
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Erstmals wird in diesem Buch ein neues, minimal-invasives Behandlungsverfahren beschrieben, das bei osteoporotischen, traumatischen oder tumorösen Veränderungen der Wirbelsäule indiziert ist. Die Technik wird in einfachen Schritten erklärt, um einen breiten, interdisziplinären Interessentenkreis zu erreichen. Da der Schwerpunkt der Technik die Osteoporose betrifft, ist auch ein spezielles Kapitel der unbedingt notwendigen Begleitmedikation gewidmet. Die neue Operationstechnik wird auch mit Alternativen zur Kyphoplastie verglichen. Ferner wird ein neuartiges Nachbehandlungskonzept speziell für die dargestellte Technik eingeführt und erklärt. Abschließend werden Listen über Referenzzentren und Abrechnungsziffern für die Krankenkassen für die deutschsprachigen Länder angeführt. Die Autoren sind seit Jahren Instruktoren für die beschriebene Operationstechnik und haben in den letzten Jahren diese neuen Methoden an verschiedenen Krankenhäusern und Universitäten in Europa gelehrt und durchgeführt.
Orthopedics. --- Neurosurgery. --- Interventional radiology . --- Rheumatology. --- Surgical oncology. --- Traumatology. --- Surgical Orthopedics. --- Interventional Radiology. --- Surgical Oncology. --- Traumatic Surgery. --- Spine --- Surgery. --- Wounds and injuries.
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Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics. Classically, on the basis of the rough correspondence between the mature/immature aspect of tumor cells and the benign/malignant biological behavior of the tumors, the histological labels contained a prognostic significance. The supposed origin of the tumors was thus a factor for prognosis. Later on, with the concept of anaplasia (Cox, 1933; Kernohan et al., 1949) new criteria were introduced for establishing the malignancy grades of tumors. Immunohistochemistry and later molecular genetics further refined the prognostic diagnoses, substantially increasing the opportunities to recognize the cell origin of tumors, beside revealing the pathogenetic mechanisms. Prognoses became more accurate, as required by the greater and more targeted possibilities of therapy.
Brain --- Tumors. --- Pathophysiology. --- Cerebrum --- Mind --- Central nervous system --- Head --- Oncology. --- Neurosciences. --- Pathology. --- Neurosurgery. --- Neurology. --- Medicine. --- Cancer Research. --- Biomedicine general. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Medicine --- Nervous system --- Neuropsychiatry --- Nerves --- Neurosurgery --- Disease (Pathology) --- Diseases --- Medicine, Preventive --- Neural sciences --- Neurological sciences --- Neuroscience --- Tumors --- Surgery --- Health Workforce --- Cancer research. --- Neurology . --- Biomedicine, general. --- Cancer research
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