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In this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume; both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.
Cell adhesion molecules. --- Metastasis. --- Cytoskeleton. --- Cell skeleton --- Skeleton, Cell --- Cytoplasm --- Cancer --- Cancer metastasis --- Dissemination of cancer --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Adhesion molecules (Cytology) --- Adhesion substances (Cytology) --- Cell adhesion substances --- Intercellular adhesion molecules --- Morphoregulatory molecules --- Biomolecules --- Desmosomes --- Hemidesmosomes --- Dissemination --- Metastasis --- Surgery. --- Oncology. --- Medicine. --- Dermatology. --- Oncology . --- Pathology. --- Cancer Research. --- Molecular Medicine. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Tumors --- Skin --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Surgery, Primitive --- Health Workforce --- Cancer research. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Cancer research
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Many plants, animals, and microbes use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives. Emphasizing the diversity of biological adhesives and associated adhesion processes, it deals with bacteria, fungi, algae, and marine and terrestrial animals. It bridges a variety of disciplines including biochemistry, molecular biology, biomechanics, bioengineering, microbiology, organism structure and function, and ultrastructure. As we learn more about the molecular and mechanical properties of these adhesives, we begin to understand why they adhere so well and how they develop cohesive strength. With this understanding comes the prospect of developing synthetic or semi-synthetic adhesives with broad applications in areas such as medicine, dentistry, and biotechnology. The book is suitable for both industrial and academic researchers.
Adhesion. --- Adhesives. --- Cell adhesion molecules. --- Cell adhesion. --- Adherence, Cell --- Cell adherence --- Adhesion --- Cell interaction --- Membrane fusion --- Junctional complexes (Epithelium) --- Adhesion molecules (Cytology) --- Adhesion substances (Cytology) --- Cell adhesion substances --- Intercellular adhesion molecules --- Morphoregulatory molecules --- Biomolecules --- Desmosomes --- Hemidesmosomes --- Agglutinants --- Bonding agents (Adhesives) --- Binders (Materials) --- Cement --- Cements, Adhesive --- Glue --- Mucilage --- Adsorption --- Cohesion --- Biochemistry. --- Microreactors. --- Biotechnology. --- Biomaterials. --- Microbiology. --- Biochemistry, general. --- Microengineering. --- Biological and Medical Physics, Biophysics. --- Microbial biology --- Biology --- Microorganisms --- Biocompatible materials --- Biomaterials --- Medical materials --- Medicine --- Biomedical engineering --- Materials --- Biocompatibility --- Prosthesis --- Chemical engineering --- Genetic engineering --- Micro-chemical engineering --- Microchannel reactors --- Microfabricated reactors --- Microreaction technology --- Mini-scale reactors --- Nano-scale reactors --- Chemical reactors --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Composition --- Biophysics. --- Biological physics. --- Bioartificial materials --- Hemocompatible materials --- Biological physics --- Physics --- Biomaterials (Biomedical materials)
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