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Quadruplex nucleic acids
Authors: --- --- --- --- --- et al.
ISBN: 9780854043743 0854043748 Year: 2006 Publisher: Cambridge : RSC Publishing,

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Abstract

Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A number of quadruplex-specific proteins have also been discovered. Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and

Sequence-specific DNA binding agents
Authors: --- --- --- --- --- et al.
ISBN: 0854043705 9780854043705 Year: 2006 Publisher: Cambridge : RSC Publishing,

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