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Microbiology --- Virus diseases --- Bacterial infections --- Mycoses --- etiology

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With the growing frequency of fungal infections even as resistance to existing antifungal agents increases, methods for finding novel drug targets and evaluating antifungal resistance have become more important than ever. In Antifungal Agents: Methods and Protocols, expert scientists describe in detail the state-of-the-art molecular methods they have optimized for studying antifungal resistance, for discovering and evaluating both new and existing antifungal drugs, and for understanding the host response and immunotherapy of such agents. Many of the protocols were developed in the laboratory and, when a method is limited to specific organisms, include alternative techniques to expand their application. The protocols follow the successful Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Antifungal Agents: Methods and Protocols offers clinician-scientists, microbiologists, and molecular biologists the productive tools they need today in order to understand and successfully develop new therapeutic agents for yeast, mold, and fungal infections.

Antifungal agents --- Medical mycology --- Mycoses --- Candida albicans --- Antifungal Agents --- Candidiasis --- Drug Resistance, Fungal --- Models, Animal --- Research --- Methodology --- Immunotherapy --- genetics --- immunology --- therapeutic use --- therapy --- Antifungal agents -- Research -- Methodology. --- Electronic books. -- local. --- Medical mycology. --- Mycoses -- Immunotherapy. --- Drug Resistance, Microbial --- Anti-Infective Agents --- Investigative Techniques --- Candida --- Biology --- Therapeutic Uses --- Biological Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Mitosporic Fungi --- Bacterial Infections and Mycoses --- Drug Resistance --- Microbiological Phenomena --- Yeasts --- Fungi --- Phenomena and Processes --- Pharmacological Phenomena --- Natural Science Disciplines --- Diseases --- Pharmacologic Actions --- Eukaryota --- Physiological Phenomena --- Disciplines and Occupations --- Chemical Actions and Uses --- Organisms --- Chemicals and Drugs --- Genetics --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Methodology. --- Immunotherapy. --- 57.08 --- 57.08 Biological techniques. Experimental methods. Equipment --- Biological techniques. Experimental methods. Equipment --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Anti-fungal agents --- Antimycotics --- Fungal inhibitory agents --- Inhibitory agents, Fungal --- Therapeutic fungicides --- Medical microbiology --- Mycology --- Pathogenic fungi --- Anti-infective agents --- Fungicides --- Emerging infectious diseases. --- Infectious Diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Antifungal agents - Research - Methodology --- Mycoses - Immunotherapy --- Candida albicans - genetics --- Candida albicans - immunology --- Antifungal Agents - therapeutic use --- Candidiasis - immunology --- Candidiasis - therapy --- Drug Resistance, Fungal - immunology

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Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases. This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.

Mycoses --- Pathogenic fungi. --- Immunological aspects. --- Fungi, Pathogenic --- Fungi --- Pathogenic microorganisms --- Medical mycology --- Fungal diseases --- Fungal infections --- Fungous diseases --- Mycosis --- Mycotic diseases --- Mycotic infections --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Thoracic surgery. --- Medical Microbiology. --- Infectious Diseases. --- Thoracic Surgery. --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Thoracic surgery --- Thoracic surgeons --- Medical microbiology. --- Infectious diseases.

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Controlled Clinical Trials as Topic --- Respiratory Tract Infections --- Bacterial Infections and Mycoses --- Disease Attributes --- Paranasal Sinus Diseases --- Diseases --- Clinical Trials as Topic --- Nose Diseases --- Respiratory Tract Diseases --- Pathologic Processes --- Epidemiologic Study Characteristics as Topic --- Otorhinolaryngologic Diseases --- Evaluation Studies as Topic --- Pathological Conditions, Signs and Symptoms --- Epidemiologic Methods --- Investigative Techniques --- Health Care Evaluation Mechanisms --- Quality of Health Care --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Public Health --- Health Care Quality, Access, and Evaluation --- Environment and Public Health --- Health Care --- Randomized Controlled Trials as Topic --- Bacterial Infections --- Sinusitis --- Acute Disease --- Medicine --- Health & Biological Sciences --- Otorhinolaryngology --- Epidemiologic Studies --- Diagnostic Techniques and Procedures.

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Controlled Clinical Trials as Topic --- Respiratory Tract Infections --- Bacterial Infections and Mycoses --- Disease Attributes --- Paranasal Sinus Diseases --- Diseases --- Clinical Trials as Topic --- Nose Diseases --- Respiratory Tract Diseases --- Pathologic Processes --- Epidemiologic Studies --- Otorhinolaryngologic Diseases --- Evaluation Studies as Topic --- Pathological Conditions, Signs and Symptoms --- Epidemiologic Methods --- Investigative Techniques --- Health Care Evaluation Mechanisms --- Quality of Health Care --- Diagnostic Techniques and Procedures. --- Public Health --- Health Care Quality, Access, and Evaluation --- Environment and Public Health --- Health Care --- Randomized Controlled Trials as Topic --- Bacterial Infections --- Sinusitis --- Acute Disease --- Medicine --- Health & Biological Sciences --- Otorhinolaryngology --- Controlled Clinical Trials as Topic. --- Respiratory Tract Infections. --- Bacterial Infections and Mycoses. --- Disease Attributes. --- Paranasal Sinus Diseases. --- Disease. --- Clinical Trials as Topic. --- Nose Diseases. --- Respiratory Tract Diseases. --- Pathologic Processes. --- Epidemiologic Studies. --- Otorhinolaryngologic Diseases. --- Evaluation Studies as Topic. --- Pathological Conditions, Signs and Symptoms. --- Epidemiologic Methods. --- Investigative Techniques. --- Health Care Evaluation Mechanisms. --- Quality of Health Care. --- Public Health. --- Health Care Quality, Access, and Evaluation. --- Environment and Public Health. --- Delivery of Health Care. --- Randomized Controlled Trials as Topic. --- Bacterial Infections. --- Sinusitis. --- Acute Disease.