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Tissue engineering : engineering principles for the design of replacement organs and tissues
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ISBN: 0197561772 1280481625 0198032404 1433701049 9780198032403 1423719883 9781423719885 9781433701047 9786610481620 6610481628 019514130X 9780195141306 0190286458 Year: 2004 Publisher: New York, New York : Oxford University Press,

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Abstract

Tissue engineering is a new field of biomedical engineering, in which synthetic materials are used together with biological components such as tissue fragments, cells, proteins to encourage tissue regeneration, regrowth, and repair. This book introduces the principles of tissue engineering in a unique way that is ideally suited for the modern engineering student. A review of developmental biology is presented early in the book, since biological development is the fundamental process of most relevance for tissue engineering. The study of development provides a pathway to basic bioengineering units on cell adhesion, migration, assembly, and transport, which are integrated in the final sections of the book into tissue engineering processes (such as cell delivery, growth factor administration, and polymeric scaffold materials).


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Biopolymer Methods in Tissue Engineering
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ISBN: 0896039676 9786610843268 1280843268 159259428X Year: 2004 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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Abstract

Because the rapidly developing field of tissue engineering encompasses all the major scientific disciplines-including materials science, polymer chemistry, biology, and medicine-it has often been difficult to uncover the full range of laboratory methods required in tissue engineering. In Biopolymer Methods in Tissue Engineering, expert laboratory researchers bring together in a standard format all the diverse laboratory methods needed to perform state-of-the-art tissue engineering research. Topics range from the synthesis, processing, and characterization of specific biomaterials, through the successful use of scaffolds in the engineering of tissues, to techniques useful in evaluating the biological quality of scaffold-engineered tissues. Subjects of special interest include the incorporation of biological molecules into scaffold biomaterials and the use of a wide range of methods and techniques to generate a comprehensive description of cell-polymer construct quality. Additional techniques can be used to develop effective in vitro models for drug evaluation or to investigate cell and tissue differentiation. Each readily reproducible protocol follows a uniform format that includes essential background information, step-by-step instructions by an expert, equipment and reagent lists, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and state-of-the-art, Biopolymer Methods in Tissue Engineering offers both advanced and novice investigators a diverse collection of readily reproducible techniques for generating living cell-polymer constructs in their laboratories and for evaluating their biological quality.

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