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Pollution --- Environmental sampling --- Gas chromatography. --- Mass spectrometry. --- Measurement --- Quality control.
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Gas chromatography. --- Mass spectrometry. --- Radiochemical analysis. --- Body fluids --- Drug dependence --- Explosives --- Hair --- Pyrolysis
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River sediments --- Organophosphorus compounds --- Polychlorinated biphenyls --- Gas chromatography. --- Electrons --- Analysis. --- Capture. --- National Water-Quality Laboratory (U.S.)
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Pilots who are considered hypertensive are closely monitored by the Federal Aviation Administration (FAA) to ensure that their hypertension is properly controlled. During the investigation of fatal civil aviation accidents, postmortem samples obtained from pilots are submitted to the FAA's Civil Aerospace Medical Institute (CAMI) for toxicological evaluation. During such evaluation, submitted samples are analyzed for prescription and nonprescription drugs, and it is common to find beta-blocker antihypertensives such as atenolol, metoprolol, and propranolol in the submitted biological samples. During a 10-year period of 1993-2002, postmortem samples from 3290 civil aviation accident pilot fatalities (cases) were received by CAMI. Toxicological evaluation of these cases revealed that 50 of the 3290 fatalities had the commonly prescribed beta-blockers, atenolol, metoprolol, and propranolol. Out of the 50 fatalities, atenolol, metoprolol, and propranolol were found to be present in 24, 19, and 7 fatalities, respectively, but the initial analysis indicated the presence of atenolol and metoprolol in 4 of these pilot fatalities. Since (i) the combined use of both drugs was not consistent with the history of the drug use by those pilots, (ii) it is uncommon to simultaneously prescribe 2 beta-blockers, and (iii) these commonly used antihypertensives have considerable amount of chemical and structural similarity (6), further examination was undertaken for those fatality cases wherein atenolol and metoprolol were initially detected. Such examination entailed selectively and simultaneously analyzing the 3 commonly used beta-blockers in the submitted biological samples and rectifying any possible analytical interference with the antihypertensives.
Air pilots --- Aircraft accidents --- Forensic toxicology --- Adrenergic beta blockers --- Adrenergic beta-Antagonists --- Atenolol --- Gas Chromatography-Mass Spectrometry. --- Metoprolol --- Propranolol --- Sensitivity and Specificity. --- Mortality --- Drug use --- Analysis. --- isolation & purification.
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Understanding Mass Spectra: A Basic Approach, Second Edition combines coverage of the principles underlying mass spectral analysis with clear guidelines on how to apply them in a laboratory setting. Completely revised from the first edition, an updated and unified approach to mass spectral interpretation emphasizes the application of basic principles from undergraduate organic, analytical, and physical chemistry courses. A detailed overview of theory and instrumentation, this useful guide contains step-by-step descriptions of interpretative strategies and convenient lists and tables detailing the information needed to solve unknowns. Other features include real-world case studies and examples, skill-building problems with clearly explained answers, and easy-to-follow explanations of the important mathematical derivations.
Mass spectrometry. --- Physicochemistry --- Spectrometric and optical chemical analysis --- Fysicochemical separation methods --- Organic spectroscopy --- Organic chemistry --- organic chemistry --- spectrometry --- gas chromatography --- isotopes --- gamma ray spectrometry --- aromatic hydrocarbon --- massaspectrometrie --- MS GC (massaspectrometrie gaschromatografie) --- isotopen --- massaspectroscopie --- organische chemie --- massaspectra --- siliconen --- GC (gas chromatography) --- fysicochemie --- spectrometrie
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Gas chromatography --- Chromatography, Gas --- 543.544 --- 543.544 Chromatographic analysis. Chromatography --- Chromatographic analysis. Chromatography --- Gas Chromatography --- Chromatography, Gas-Liquid --- Chromatographies, Gas --- Chromatographies, Gas-Liquid --- Chromatography, Gas Liquid --- Gas Chromatographies --- Gas-Liquid Chromatographies --- Gas-Liquid Chromatography --- Gas-liquid chromatography --- GLC (Chromatographic analysis) --- Vapor-phase chromatography --- Chromatographic analysis
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This highly successful textbook, acclaimed for its comprehensiveness, accuracy, and its many excellent illustrations and photographs now comes in its second edition. Completely revised and substantially extended it offers: New chapter on **Tandem Mass Spectrometry** covering instrumentation, methods for ion activation (CID, ECD, ETD, IRMPD), and applications New chapter on **Ambient Mass Spectrometry** (DART, DESI, and more) New chapter on **Inorganic Mass Spectrometry** including element speciation and imaging **Learning Objectives** for all chapters **Advanced Instrumentation** such as orbitraps, linear ion traps, tandem TOFs, FT-ICR and the highly variable hybrid instruments Updated **Problems and Solutions website** (www.ms-textbook.com) ***Jürgen H. Gross*** provides in-depth explanations of concepts, methods, and techniques. Students and professionals alike are guided step-by-step from the basics to the successful application of mass spectrometry. Starting from the very principles of gas-phase ion chemistry, isotopic composition, and accurate mass, ***Jürgen H. Gross*** leads through the design of all types of mass analyzers and ionization methods to mass spectral interpretation and coupling techniques. His book offers a balanced mixture of practice-oriented information and theoretical background supported by a wealth of references. Keywords Analytical Chemistry - CID, IRMPD, ECD, ETD - Chemical Ionization - DART, DESI, DAPCI - Electron Ionization - Electrospray Ionization - Fast Atom Bombardment - Field Desorption - Field Ionization - Inorganic Mass Spectrometry - Isotope Ratio - LIFDI - MALDI - Mass Spectrometry - TOF/TOF - Tandem Mass Spectrometry - Textbook
spectrometrie --- fysicochemie --- gas chromatography --- organic chemistry --- Organic chemistry --- MS GC (massaspectrometrie gaschromatografie) --- Spectrometric and optical chemical analysis --- massaspectrometrie --- isotopes --- organische chemie --- isotopen --- Physicochemistry --- spectrometry --- Fysicochemical separation methods --- GC (gaschromatografie) --- Organic spectroscopy --- Spectrométrie --- Spectrometry --- methods --- Analytische chemie --- Spectrometrie --- Analytical biochemistry. --- Chemistry. --- Chemistry, Physical organic. --- Environmental toxicology. --- Polymers. --- Proteomics. --- Mass spectrometry --- Ionization --- Analytical Chemistry --- Chemistry --- Physical Sciences & Mathematics --- Monograph --- GC (gas chromatography) --- Mass spectra --- Mass spectrograph --- Mass spectroscopy --- Mass spectrum analysis --- Mass (Physics) --- Nuclear spectroscopy --- Spectrum analysis --- Scission (Chemistry) --- Analytical chemistry. --- Ecotoxicology. --- Physical chemistry. --- Polymers . --- Physical measurements. --- Measurement . --- Analytical Chemistry. --- Physical Chemistry. --- Polymer Sciences. --- Measurement Science and Instrumentation. --- Measuring --- Mensuration --- Mathematics --- Technology --- Metrology --- Physical measurements --- Measurements, Physical --- Mathematical physics --- Measurement --- Molecular biology --- Proteins --- Polymere --- Polymeride --- Polymers and polymerization --- Macromolecules --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Ecotoxicology --- Pollutants --- Pollution --- Environmental health --- Toxicology --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Analytic
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