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The bacterium Escherichia coli – E. coli for short – has long been the organism of choice for unraveling biochemical pathways, deciphering the genetic code, learning how DNA is replicated and read, and even for manufacturing proteins of commercial interest. For some thirty years, it also has been a model for studying the molecular biology of behavior. E. coli swims in a purposeful manner, propelled by long thin helical filaments, each driven at its base by a reversible rotary engine. As a microscopic organism immersed in an aqueous environment, it has mastered physical constraints utterly different from any that we know, devising sensors, comparators, and motors on the nanometer scale. This cross-disciplinary monograph describes these feats in a manner accessible to scientists, engineers, and others not trained in microbiology who would like to learn more about living machines. It treats the history of the subject, the physiology, physics, biochemistry and genetics, largely from first principles. It is all about a small but remarkably sophisticated friend who lives in your gut. Topics discussed include: How does E. coli move about? How do cells decide whether life is getting better or worse? What is the machinery that makes this behavior possible? How is the construction of this machinery programmed? How does this machinery work? What remains to be discovered?

Escherichia coli --- Microbiologie --- Bacteriën --- Microorganisms -- Motility. --- Escherichia --- Enterobacteriaceae --- Gammaproteobacteria --- Gram-Negative Facultatively Anaerobic Rods --- Proteobacteria --- Life sciences. --- Medical microbiology. --- Molecular biology. --- Bacteriology. --- Biophysics. --- Biological physics. --- Life Sciences. --- Biophysics and Biological Physics. --- Medical Microbiology. --- Molecular Medicine. --- Escherichia coli. --- Microorganisms --- Motility. --- Microbiology. --- Medicine. --- Biological and Medical Physics, Biophysics. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Biological physics --- Biology --- Medical sciences --- Physics --- Microbiology --- Microorganisms. --- Germs --- Micro-organisms --- Microbes --- Microscopic organisms --- Organisms --- Bacteriën

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Biological Nanostructures and Applications of Nanostructures in Biology: Electrical, Mechanical, and Optical Properties contains reviews and discussions of contemporary and relevant topics dealing with the interface between the science and technology of nanostructures and the science of biology. Moreover, this book supplements these past groundbreaking discoveries with discussions of promising new avenues of research that reveal the enormous potential of emerging approaches in nanobiotechnology. The topics include: - Biomedical applications of semiconductor quantum dots, - Integrating and tagging biological structures with nanoscale quantum dots, - Applications of carbon nanotubes in bioengineering, - Nanophysical properties of living cells, - Bridging natural nanotubes with fabricated nanotubes, - Bioinspired approaches to building nanoscale devices and systems, - Hairpin formation in polynucleotides. This state-of-the-art survey of key developments in nanotechnology - as they apply to bioengineering and biology - is essential reading for all academics, biomedical engineers, medical physicists, and industry professionals wishing to take advantage of the latest developments and highly-promising discoveries in nanoscience underlying applications in bioengineering and biology.

Nanostructures. --- Biomedical materials. --- Biotechnology. --- Life sciences. --- Biomedical engineering. --- Engineering. --- Radiology, Medical. --- Life Sciences, general. --- Biomedical Engineering and Bioengineering. --- Biological and Medical Physics, Biophysics. --- Engineering, general. --- Imaging / Radiology. --- Biophysics. --- Biological physics. --- Radiology. --- Radiological physics --- Physics --- Radiation --- Construction --- Industrial arts --- Technology --- Biological physics --- Biology --- Medical sciences --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Biosciences --- Sciences, Life --- Science --- Biomedical materials --- Biotechnology --- Biocompatibility. --- Research.

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Biophysics --- DNA --- Nonlinear mechanics --- Mechanics, Nonlinear --- Deoxyribonucleic acid --- Desoxyribonucleic acid --- Thymonucleic acid --- TNA (Nucleic acid) --- Biological physics --- Conformation --- Structure --- Mechanics, Analytic --- Deoxyribose --- Nucleic acids --- Genes --- Biology --- Medical sciences --- Physics

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This book has its origin in my experience as a teacher of pharmacokinetics in many universities in four different continents. It was not my intention to write a popular book; what distinguishes this one from many others on the same subject is its large use of algebra and calculus. For this I make no apologies; in fact a serious study of pharmacokinetics without the help of mathematics is, in my opinion, impossible. The exact definition of many pharmacokinetic quantities, even the most common, and the correct use of many equations, even the most simple, requires the constant use of mathematical language. On the other hand I have made a considerable effort to use only elementary algebra and elementary calculus, as commonly taught in most introductory university courses. For the few exceptions, when less common mathematical concepts were needed, I have supplied the necessary explanations in four appendices. The first three chapters are a general introduction to the scientific method. Chapters 4 to 12 show different specific methods to deal with pharmacokinetic pr- lems. There is considerable overlap among those chapters; this is intentional and its p- pose is to convince the reader that every problem can be solved in more than one way, including ways that were not mentioned in this book and that intelligent readers can find for their own pleasure. Chapters 13 to 17 show how different parameters of importance in pharmacokinetics can be exactly defined and measured.

Pharmacokinetics. --- Toxicology. --- Veterinary medicine. --- Pharmacy. --- Radiology, Medical. --- Pharmacology/Toxicology. --- Veterinary Medicine/Veterinary Science. --- Diagnostic Radiology. --- Biological and Medical Physics, Biophysics. --- Pharmacology. --- Radiology. --- Biophysics. --- Biological physics. --- Biological physics --- Biology --- Medical sciences --- Physics --- Radiological physics --- Radiation --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Animal health --- Animals --- Domestic animals --- Livestock --- Drug effects --- Medical pharmacology --- Chemicals --- Chemotherapy --- Pharmacy --- Diseases --- Losses --- Physiological effect --- Drug kinetics --- Kinetics, Drugs --- Chemical kinetics --- Kinetics --- Pharmacokinetics --- Metabolism

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About the Series: Bioelectric Engineering presents state-of-the-art discussions on modern biomedical engineering with respect to applications of electrical engineering and information technology in biomedicine. This focus affirms Springer’s commitment to publishing important reviews of the broadest interest to biomedical engineers, bioengineers, and their colleagues in affiliated disciplines. Recent volumes have covered modeling and imaging of bioelectric activity, neural engineering, biosignal processing, bionanotechnology, among other topics. Key Features of this Volume: Neural Engineering, Bioelectric Engineering Volume 2, contains reviews and discussions of contemporary and relevant topics by leading investigators in the field. It is intended to serve as a textbook at the graduate and advanced undergraduate level in a bioengineering curriculum. The topics include: – Neural Prostheses – Neural Interfacing – Neural Robotics – Functional Neural Stimulation – Neural Imaging – Neural Computation – Neural Networks – Neural System Identification and Prediction – Retinal Neuroengineering This principles and applications approach to neural engineering is essential reading for all academics, biomedical engineers, neuroscientists, neurophysiologists, and industry professionals wishing to take advantage of the latest and greatest in this emerging field. About the Editor: Bin He, PhD., IEEE Fellow, is a leading figure in the field of bioelectric engineering. An internationally recognized scientist with numerous publications, Dr. He has served as the President of the International Society of Bioelectromagnetism and as an Associate or Guest Editor for nine international journals in the field of biomedical engineering. Dr. He is currently Professor of Biomedical Engineering at the University of Minnesota.

Nanostructures. --- Biomedical materials. --- Biotechnology. --- Chemical engineering --- Genetic engineering --- Biocompatible materials --- Biomaterials --- Medical materials --- Medicine --- Biomedical engineering --- Materials --- Biocompatibility --- Prosthesis --- Nanoscience --- Physics --- Medicine. --- Biomedical engineering. --- Neurosciences. --- Radiology, Medical. --- Biomedicine general. --- Biomedical Engineering and Bioengineering. --- Biological and Medical Physics, Biophysics. --- Imaging / Radiology. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Biophysics. --- Biological physics. --- Radiology. --- Biomedicine, general. --- Health Workforce --- Radiological physics --- Radiation --- Biological physics --- Biology