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Biotechnologie --- Biotechnology --- Bioréacteur --- Bioreactors --- Modèle --- Models --- Surveillance --- monitoring --- Modèle de simulation --- Simulation models --- Modèle dynamique --- Dynamic models --- 66.098 --- -Biochemical engineering --- -Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Chemical engineering --- Biochemical reactors --- Reactors, Biochemical --- Biochemical engineering --- Chemical reactors --- Biological processes. Biotechnology --- Computer simulation --- Equipment and supplies --- -Biological processes. Biotechnology --- 66.098 Biological processes. Biotechnology --- -66.098 Biological processes. Biotechnology --- Bio-process engineering --- Basic Sciences. Biotechnology -- Biotechnology (General). --- Computer simulation.
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This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.
General biochemistry --- biotechnologie --- biochemie --- Biotechnology --- thermodynamics --- biochemistry --- Thermodynamics --- bioreactoren --- bioengineering --- Bioreactors --- Bioréacteurs --- Bioréacteurs --- Environmental engineering. --- Biotechnology. --- Biochemical engineering. --- Biochemistry. --- Environmental Engineering/Biotechnology. --- Biochemical Engineering. --- Biochemistry, general. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Chemical engineering --- Genetic engineering --- Environmental control --- Environmental effects --- Environmental stresses --- Engineering --- Environmental health --- Environmental protection --- Pollution --- Sustainable engineering --- Composition
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This volume offers a broad and interdisciplinary view of modern approaches to drug discovery as used by pharmaceutical companies and research institutes. It comprehensively covers proteomics, bioinformatics, screening techniques such as high-throughput-, natural compounds-, and NMR-based-screenings, combinatorial chemistry, compound library design, ligand- and structure-based drug design and pharmacokinetic approaches. Each of the thirteen chapters reviews the theory, background and application of a key technology in drug discovery, complemented by an extensive list of references to the original literature. This concise source of information will be useful for researchers, both in industry and academia, as well as students in the fields of medicinal, pharmaceutical and computational chemistry, bioinformatics, biochemistry, molecular biology and pharmacology. Features and benefits - Structure-based drug design, molecular modeling, bioinformatics, screening methods, combinatorial chemistry and physicochemical concepts in drug discovery are comprehensively covered. - The volume is written from the viewpoint of the "drug researcher" working in the pharmaceutical industry, and also presents chapters on novel approaches developed in academia. - Offers high practical value for young scientists who need a quick introduction to the topic. - Provides an overview of the drug discovery process, particularly for specialized scientists working in drug discovery and pharma-managers.
Drugs --- Pharmaceutical technology --- Pharmaceutical chemistry --- QSAR (Biochemistry) --- Combinatorial chemistry --- Médicaments --- Techniques pharmaceutiques --- Chimie pharmaceutique --- Relations structure-activité quantitatives (Biochimie) --- Chimie combinatoire --- Research --- Data processing --- Recherche --- Informatique --- Combinatorial chemistry. --- Pharmaceutical technology. --- Chemistry, Pharmaceutical --- Biopharmaceutics. --- Drug Compounding --- Research. --- Data processing. --- methods. --- QSAR (Biochemistry). --- Médicaments --- Relations structure-activité quantitatives (Biochimie) --- Methods. --- Pharmacology. --- Analytical chemistry. --- Biochemical engineering. --- Organic chemistry. --- Medical biochemistry. --- Proteomics. --- Pharmacology/Toxicology. --- Analytical Chemistry. --- Biochemical Engineering. --- Organic Chemistry. --- Medical Biochemistry. --- Molecular biology --- Proteins --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology --- Organic chemistry --- Chemistry --- Bio-process engineering --- Bioprocess engineering --- Biotechnology --- Chemical engineering --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Analytic --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Pharmacy --- Physiological effect
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