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Biotechnologie --- Biotechnology --- Bioréacteur --- Bioreactors --- Modèle --- Models --- Surveillance --- monitoring --- Modèle de simulation --- Simulation models --- Modèle dynamique --- Dynamic models --- 66.098 --- -Biochemical engineering --- -Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Chemical engineering --- Biochemical reactors --- Reactors, Biochemical --- Biochemical engineering --- Chemical reactors --- Biological processes. Biotechnology --- Computer simulation --- Equipment and supplies --- -Biological processes. Biotechnology --- 66.098 Biological processes. Biotechnology --- -66.098 Biological processes. Biotechnology --- Bio-process engineering --- Basic Sciences. Biotechnology -- Biotechnology (General). --- Computer simulation.

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This volume offers a broad and interdisciplinary view of modern approaches to drug discovery as used by pharmaceutical companies and research institutes. It comprehensively covers proteomics, bioinformatics, screening techniques such as high-throughput-, natural compounds-, and NMR-based-screenings, combinatorial chemistry, compound library design, ligand- and structure-based drug design and pharmacokinetic approaches. Each of the thirteen chapters reviews the theory, background and application of a key technology in drug discovery, complemented by an extensive list of references to the original literature. This concise source of information will be useful for researchers, both in industry and academia, as well as students in the fields of medicinal, pharmaceutical and computational chemistry, bioinformatics, biochemistry, molecular biology and pharmacology. Features and benefits - Structure-based drug design, molecular modeling, bioinformatics, screening methods, combinatorial chemistry and physicochemical concepts in drug discovery are comprehensively covered. - The volume is written from the viewpoint of the "drug researcher" working in the pharmaceutical industry, and also presents chapters on novel approaches developed in academia. - Offers high practical value for young scientists who need a quick introduction to the topic. - Provides an overview of the drug discovery process, particularly for specialized scientists working in drug discovery and pharma-managers.

Drugs --- Pharmaceutical technology --- Pharmaceutical chemistry --- QSAR (Biochemistry) --- Combinatorial chemistry --- Médicaments --- Techniques pharmaceutiques --- Chimie pharmaceutique --- Relations structure-activité quantitatives (Biochimie) --- Chimie combinatoire --- Research --- Data processing --- Recherche --- Informatique --- Combinatorial chemistry. --- Pharmaceutical technology. --- Chemistry, Pharmaceutical --- Biopharmaceutics. --- Drug Compounding --- Research. --- Data processing. --- methods. --- QSAR (Biochemistry). --- Médicaments --- Relations structure-activité quantitatives (Biochimie) --- Methods. --- Pharmacology. --- Analytical chemistry. --- Biochemical engineering. --- Organic chemistry. --- Medical biochemistry. --- Proteomics. --- Pharmacology/Toxicology. --- Analytical Chemistry. --- Biochemical Engineering. --- Organic Chemistry. --- Medical Biochemistry. --- Molecular biology --- Proteins --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology --- Organic chemistry --- Chemistry --- Bio-process engineering --- Bioprocess engineering --- Biotechnology --- Chemical engineering --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Analytic --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Pharmacy --- Physiological effect