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Longevity : the biology and demography of life span
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ISBN: 0691224080 Year: 2003 Publisher: Princeton, New Jersey : Princeton University Press,

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Abstract

Despite our deep interest in mortality, little is known about why some individuals live to middle age and others to extreme old age. Life span, mortality, and aging present some of the most profound mysteries in biology. In Longevity, James Carey draws on unprecedented data to develop a biological and demographic framework for identifying the key factors that govern aging, life span, and mortality in humans and other animals. Carey presents the results of a monumental, twelve-year, National Institute on Aging-funded research project on the determinants of longevity using data from the life tables of five million Mediterranean fruit flies, the most comprehensive set of life table studies ever on the mortality dynamics of a single species. He interprets the fruit fly data within the context of human aging and the aging process in general to identify the determinants of mortality. Three key themes emerge: the absence of species-specific life span limits, the context-specific nature of the mortality rate, and biodemographic linkages between longevity and reproduction. A powerful foundation for the emerging field of biodemography and a rich framework for considering the future of human life span, Longevity will be an indispensable resource for readers from a range of fields including population biology, demography, gerontology, ecology, evolutionary biology, and medical research.

Keywords

Longevity. --- Ageing. --- Amphibian. --- Bacteria. --- Baseline Study. --- Behavior. --- Biodemography. --- Biological system. --- Biologist. --- Biology. --- Biomedicine. --- Brain size. --- Centenarian. --- Ceratitis capitata. --- Ceteris paribus. --- Coevolution. --- Confidence interval. --- Correlation coefficient. --- Degenerative disease. --- Demographic dividend. --- Demography. --- Disease. --- Drosophila melanogaster. --- Drosophila. --- Ecology. --- Egg as food. --- Emergence. --- Environmental factor. --- Estimation. --- Eusociality. --- Evolution. --- Evolutionary biology. --- Extrapolation. --- Fecundity. --- Female. --- Fertility. --- Germ cell. --- Gerontology. --- Grandparent. --- Heritability. --- Hibernation. --- Hominidae. --- Homo erectus. --- Homo habilis. --- Homo sapiens. --- Housefly. --- Hydrolysate. --- Insect. --- Invertebrate. --- James Vaupel. --- Jeanne Calment. --- Kin selection. --- Larva. --- Late-life mortality deceleration. --- Leveling (philosophy). --- Life expectancy. --- Life history theory. --- Life table. --- Logarithm. --- Macronucleus. --- Mammal. --- Mating. --- Maximum life span. --- Menopause. --- Middle age. --- Model organism. --- Mortality rate. --- Multicellular organism. --- Natural selection. --- Nematode. --- Nutrient. --- Nutrition. --- Offspring. --- Old age. --- Opportunity cost. --- Organism. --- Oviparity. --- Parental investment. --- Probability. --- Protein. --- Quality of life. --- Rejuvenation (aging). --- Reproduction. --- Reproductive success. --- Rodent. --- Sampling error. --- Senescence. --- Sex differences in humans. --- Sex ratio. --- Sexual dimorphism. --- Sexual maturity. --- Sexual reproduction. --- Shoaling and schooling. --- Sociality. --- Species. --- Standard deviation. --- Survival rate. --- Trade-off. --- Vertebrate. --- Year.

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