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Quantitative trait loci : methods and protocols
Authors: ---
ISBN: 0896039277 9786610821389 1280821388 1592591760 Year: 2002 Publisher: Totowa, N.J. : Humana Press,

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Abstract

Statistical methods for the analysis of quantitative trait locus (QTL), in conjunction with genome-wide screening technologies, are today yielding exciting results in the study of human disease, experimental organisms, and agriculture. In Quantitative Trait Loci: Methods and Protocols, Drs. Nicola Camp and Angela Cox have assembled a highly experienced panel of statistical geneticists who demonstrate in a step-by-step fashion how to use this powerful methodology and associated software for the detection and fine mapping of quantitative trait loci. Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and useful variations and/or extensions to standard methods are included that ease the reader toward understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov chain Monte Carlo method for joint linkage and segregation analysis. Up-to-date and highly practical, Quantitative Trait Loci: Methods and Protocols makes available to nonmathematical investigators a step-by-step guide to the productive use today of all the latest techniques for localizing genes involved in complex quantitative traits.

Mathematics of genome analysis
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ISBN: 0521585260 0521585171 0511018533 9786612389085 1282389084 0511642903 0511202202 0511613199 0511555903 0511054157 1107114101 9780511018534 9780511613197 9780511054150 9780521585170 9780521585262 9781107114104 6612389087 9781282389083 9780511642906 9780511202209 9780511555909 Year: 2002 Volume: 17 Publisher: Cambridge Cambridge University Press

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Abstract

This short textbook on the mathematics of genome analysis presents a brief description of several ways in which mathematics and statistics are being used in genome analysis and sequencing. It will be of interest not only to students but also to professional mathematicians curious about the subject.

Keywords

Biomathematics. Biometry. Biostatistics --- Mathematical statistics --- Genetics --- Gene mapping --- Génétique --- Cartes chromosomiques --- Mathematical models --- Statistical methods --- Modèles mathématiques --- Méthodes statistiques --- 51-7 --- 57 --- 519.2 --- -Genetics --- -Gene mapping --- -Chromosome mapping --- Genetic mapping --- Genome mapping --- Linkage mapping (Genetics) --- Mapping, Gene --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Mathematical studies and methods in other sciences. Scientific mathematics. Actuarial mathematics. Biometrics. Econometrics etc. --- Biologische wetenschappen in het algemeen. Biologie --- Probability. Mathematical statistics --- Technique --- Mathematical models. --- Statistical methods. --- Gene mapping. --- Gene mapping - Mathematical models. --- Genetics. --- Statistics as Topic --- Documentation --- Genetic Techniques --- Genetic Structures --- Models, Theoretical --- Information Services --- Epidemiologic Methods --- Investigative Techniques --- Genetic Phenomena --- Health Care Evaluation Mechanisms --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Quality of Health Care --- Public Health --- Information Science --- Phenomena and Processes --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Health Care --- Chromosome Mapping --- Molecular Sequence Data --- Genome --- Models, Statistical --- Health & Biological Sciences --- -Mathematical studies and methods in other sciences. Scientific mathematics. Actuarial mathematics. Biometrics. Econometrics etc. --- 519.2 Probability. Mathematical statistics --- 51-7 Mathematical studies and methods in other sciences. Scientific mathematics. Actuarial mathematics. Biometrics. Econometrics etc. --- -519.2 Probability. Mathematical statistics --- Chromosome mapping --- Génétique --- Modèles mathématiques --- Méthodes statistiques --- Biomathematics --- Mathematical studies and methods in other sciences. Scientific mathematics. Actuarial mathematics. Biometrics. Econometrics etc

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