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2002 (6)

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An introduction to metabolic and cellular engineering
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ISBN: 981238877X 9789812388773 9789810248369 9810248369 9789810248352 9789812388773 9810248350 9810248369 Year: 2002 Publisher: River Edge, NJ : World Scientific,

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Abstract

Metabolic and cellular engineering, as presented in this book, is a powerful alliance of two technologies: genetics â€" molecular biology and fermentation technology. Both are driven by continuous refinement of the basic understanding of metabolism, physiology and cellular biology (growth, division, differentiation), as well as the development of new mathematical modeling techniques. The authorsâ€TM approach is original in that it integrates several disciplines into a coordinated scheme, i.e. microbial physiology and bioenergetics, thermodynamics and enzyme kinetics, biomathematics and biochemi

Bioprocess engineering : basic concepts.
Authors: ---
ISBN: 0130819085 Year: 2002 Publisher: Englewood Cliffs (N.J.) Prentice Hall

Glycosylation
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ISBN: 128020012X 9786610200122 0306475251 1402007337 Year: 2002 Publisher: Dordrecht : Springer Netherlands : Imprint: Springer,

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The analysis and modification of glycans of recombinant proteins continues to be active and challenging area of research and for the successful manufacture of these proteins. In Cell Engineering, volume 3: Glycosylation, Dr. Mohammed Al-Rubeai has compiled a group of articles that will provide research workers not only with reviews of the advances that have been made in all facets of the subject but with an in-depth assessment of the state of the art methodology and the various approaches for the improvement of glycoprotein production. Particularly important in this respect is the advances made in the development of genetically engineered host cell lines with novel glycosylation properties, as well as the integration of mass spectrophotometric analysis with separation techniques. This volume is intended not only for research students and senior scientists in cell culture and glycobiology, but also for industrial biotechnologists and biochemical engineers interested in the production of therapeutic glycoproteins, virus vector and ex vivo expansion of human cells for medical treatment.

Advances in bioprocessing engineering
Authors: ---
ISBN: 1281908894 9786611908898 9812706585 9789812706584 981024696X 9789810246969 9810246978 9789810246976 9781281908896 6611908897 Year: 2002 Publisher: River Edge, NJ : World Scientific Pub.,

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This book consists of peer-reviewed articles reporting on the latest developments in several food engineering and agricultural processing laboratories at US land-granted universities. The contributors are leading experts in their respective fields.The topics covered in the book include new food processing technologies (such as high voltage electric field processing and microwave sterilization/pasteurization), conversion of agricultural by-products into high quality refined cellulose or biodegradable plastics, and advances in machine vision inspection and sorting techniques for fruit and vegeta

Pathway analysis and optimization in metabolic engineering
Authors: ---
ISBN: 9780511546334 9780521800389 9780521177481 0521800382 0511063229 9780511063220 0511546335 0511119259 9780511119255 051107168X 9780511071683 128016042X 9781280160424 1107130190 9781107130197 0521177480 9786610160426 6610160422 1139146963 9781139146968 0511056893 9780511056895 0511307470 9780511307478 Year: 2002 Publisher: New York : Cambridge University Press,

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Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.

Molecular modeling and simulation : an interdisciplinary guide
Author:
ISBN: 038795404X 1475758936 9786610009565 128000956X 0387224645 9780387954042 Year: 2002 Volume: v. 21 Publisher: New York : Springer,

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Abstract

Science is a way of looking, reverencing. And the purpose of all science, like living, which amounts to the same thing, is not the ac­ cumulation of gnostic power, the fixing of formulas for the name of God, the stockpiling of brutal efficiency, accomplishing the sadistic myth of progress. The purpose of science is to revive and cultivate a perpetual state of wonder. For nothing deserves wonder so much as our capacity to experience it. Roald Hoffman and Shira Leibowitz Schmidt, in Old Wine, New Flasks: Re. flections on Science and Jewish Tradition (W. H. Freeman, 1997). Challenges in Teaching Molecular Modeling This textbook evolved from a graduate course termed Molecular Modeling intro­ duced in the fall of 1996 at New York University. The primary goal of the course is to stimulate excitement for molecular modeling research - much in the spirit of Hoffman and Leibowitz Schmidt above - while providing grounding in the discipline. Such knowledge is valuable for research dealing with many practical problems in both the acadernic and industrial sectors, from developing treatments for AIDS (via inhibitors to the protease enzyme of the human imrnunodeficiency virus, HIV-1) to designing potatoes that yie1d spot-free potato chips (via trans­ genic potatoes with altered carbohydrate metabolism). In the course of writing xii Preface this text, the notes have expanded to function also as an introduction to the field for scientists in other disciplines by providing a global perspective into problems and approaches, rather than a comprehensive survey.

Keywords

Biomolecules --- Biomolécules --- Models. --- Models --- Computer simulation. --- Modèles --- Simulation par ordinateur --- Computer simulation --- 539.2 --- Properties and structure of molecular systems --- Biomolecules -- Models -- Computer simulation. --- Biomolecules -- Models. --- Electronic books. -- local. --- Models, Molecular --- Computer Simulation --- Models, Theoretical --- Computing Methodologies --- Information Science --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Physical & Theoretical Chemistry --- Chemistry --- Physical Sciences & Mathematics --- Biology --- Health & Biological Sciences --- Biochemistry --- Biology - General --- 539.2 Properties and structure of molecular systems --- Biomolécules --- Modèles --- Biological molecules --- Molecules --- Molecular biology --- Models&delete& --- Biochemistry. --- Biochemical engineering. --- Biomathematics. --- Biophysics. --- Biological physics. --- Biochemistry, general. --- Biochemical Engineering. --- Simulation and Modeling. --- Mathematical and Computational Biology. --- Biological and Medical Physics, Biophysics. --- Biological physics --- Medical sciences --- Physics --- Mathematics --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Bio-process engineering --- Bioprocess engineering --- Biotechnology --- Chemical engineering --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Composition --- Biomolecules - Models --- Biomolecules - Models - Computer simulation

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