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Metabolic and cellular engineering, as presented in this book, is a powerful alliance of two technologies: genetics â€" molecular biology and fermentation technology. Both are driven by continuous refinement of the basic understanding of metabolism, physiology and cellular biology (growth, division, differentiation), as well as the development of new mathematical modeling techniques. The authorsâ€TM approach is original in that it integrates several disciplines into a coordinated scheme, i.e. microbial physiology and bioenergetics, thermodynamics and enzyme kinetics, biomathematics and biochemi
Biochemical engineering. --- Metabolism. --- Anabolism --- Catabolism --- Metabolism, Primary --- Primary metabolism --- Biochemistry --- Physiology --- Bio-process engineering --- Bioprocess engineering --- Biotechnology --- Chemical engineering
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Biochemical engineering --- 66.098 --- 66.098 Biological processes. Biotechnology --- Biological processes. Biotechnology --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- General biochemistry --- biochemistry --- bioengineering --- bioreactoren --- biochemie --- biotechnologie --- enzymen
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The analysis and modification of glycans of recombinant proteins continues to be active and challenging area of research and for the successful manufacture of these proteins. In Cell Engineering, volume 3: Glycosylation, Dr. Mohammed Al-Rubeai has compiled a group of articles that will provide research workers not only with reviews of the advances that have been made in all facets of the subject but with an in-depth assessment of the state of the art methodology and the various approaches for the improvement of glycoprotein production. Particularly important in this respect is the advances made in the development of genetically engineered host cell lines with novel glycosylation properties, as well as the integration of mass spectrophotometric analysis with separation techniques. This volume is intended not only for research students and senior scientists in cell culture and glycobiology, but also for industrial biotechnologists and biochemical engineers interested in the production of therapeutic glycoproteins, virus vector and ex vivo expansion of human cells for medical treatment.
Glycoconjugates. --- Glycosylation. --- Animal cell biotechnology. --- Genetic engineering. --- Morphology (Animals). --- Biochemical engineering. --- Biochemistry. --- Animal Anatomy / Morphology / Histology. --- Biochemical Engineering. --- Animal Biochemistry. --- Biochemistry, general. --- Animal anatomy. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Animal anatomy --- Animals --- Physiology --- Composition --- Anatomy --- Glycoconjugates --- Biotechnology. --- Anatomy, Comparative. --- Animal Anatomy. --- Chemical Bioengineering. --- Chemical Biology.
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This book consists of peer-reviewed articles reporting on the latest developments in several food engineering and agricultural processing laboratories at US land-granted universities. The contributors are leading experts in their respective fields.The topics covered in the book include new food processing technologies (such as high voltage electric field processing and microwave sterilization/pasteurization), conversion of agricultural by-products into high quality refined cellulose or biodegradable plastics, and advances in machine vision inspection and sorting techniques for fruit and vegeta
Agricultural engineering. --- Biochemical engineering. --- Food industry and trade. --- Food --- Food preparation industry --- Food processing --- Food processing industry --- Food technology --- Food trade --- Agricultural processing industries --- Processed foods --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Bioengineering --- Engineering --- Farm equipment --- Food biotechnology --- Genetically modified foods --- Biotechnology. --- Processing --- Agricultural engineering --- Biochemical engineering --- Food industry and trade --- 66.098 --- Biochemical processes
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Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.
Biochemical engineering --- Mathematical optimization. --- System theory. --- Systems, Theory of --- Systems science --- Science --- Optimization (Mathematics) --- Optimization techniques --- Optimization theory --- Systems optimization --- Mathematical analysis --- Maxima and minima --- Operations research --- Simulation methods --- System analysis --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Mathematical models. --- Philosophy
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Science is a way of looking, reverencing. And the purpose of all science, like living, which amounts to the same thing, is not the ac cumulation of gnostic power, the fixing of formulas for the name of God, the stockpiling of brutal efficiency, accomplishing the sadistic myth of progress. The purpose of science is to revive and cultivate a perpetual state of wonder. For nothing deserves wonder so much as our capacity to experience it. Roald Hoffman and Shira Leibowitz Schmidt, in Old Wine, New Flasks: Re. flections on Science and Jewish Tradition (W. H. Freeman, 1997). Challenges in Teaching Molecular Modeling This textbook evolved from a graduate course termed Molecular Modeling intro duced in the fall of 1996 at New York University. The primary goal of the course is to stimulate excitement for molecular modeling research - much in the spirit of Hoffman and Leibowitz Schmidt above - while providing grounding in the discipline. Such knowledge is valuable for research dealing with many practical problems in both the acadernic and industrial sectors, from developing treatments for AIDS (via inhibitors to the protease enzyme of the human imrnunodeficiency virus, HIV-1) to designing potatoes that yie1d spot-free potato chips (via trans genic potatoes with altered carbohydrate metabolism). In the course of writing xii Preface this text, the notes have expanded to function also as an introduction to the field for scientists in other disciplines by providing a global perspective into problems and approaches, rather than a comprehensive survey.
Biomolecules --- Biomolécules --- Models. --- Models --- Computer simulation. --- Modèles --- Simulation par ordinateur --- Computer simulation --- 539.2 --- Properties and structure of molecular systems --- Biomolecules -- Models -- Computer simulation. --- Biomolecules -- Models. --- Electronic books. -- local. --- Models, Molecular --- Computer Simulation --- Models, Theoretical --- Computing Methodologies --- Information Science --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Physical & Theoretical Chemistry --- Chemistry --- Physical Sciences & Mathematics --- Biology --- Health & Biological Sciences --- Biochemistry --- Biology - General --- 539.2 Properties and structure of molecular systems --- Biomolécules --- Modèles --- Biological molecules --- Molecules --- Molecular biology --- Models&delete& --- Biochemistry. --- Biochemical engineering. --- Biomathematics. --- Biophysics. --- Biological physics. --- Biochemistry, general. --- Biochemical Engineering. --- Simulation and Modeling. --- Mathematical and Computational Biology. --- Biological and Medical Physics, Biophysics. --- Biological physics --- Medical sciences --- Physics --- Mathematics --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Bio-process engineering --- Bioprocess engineering --- Biotechnology --- Chemical engineering --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Composition --- Biomolecules - Models --- Biomolecules - Models - Computer simulation
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