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Biomechanics --- Biological control systems --- Biology --- Models, Biological --- Mathematical models --- Biomechanics. --- Models, Biological. --- Biomécanique --- Régulation (Biologie) --- Biologie --- Modèles biologiques --- Biological control systems. --- Modèles mathématiques --- Mathematical models. --- Biological mechanics --- Mechanical properties of biological structures --- Biocybernetics --- Biofeedback --- Biological cybernetics --- Biological regulation --- Control biophysics --- Control systems, Biological --- Control theory in biology --- Regulation, Biological --- Biological Model --- Biological Models --- Model, Biological --- Models, Biologic --- Biologic Model --- Biologic Models --- Model, Biologic --- Biomechanical Phenomena. --- Biomechanic Phenomena --- Mechanobiological Phenomena --- Kinematics --- Biomechanic Phenomenas --- Phenomena, Biomechanic --- Phenomena, Biomechanical --- Phenomena, Mechanobiological --- Phenomenas, Biomechanic --- Biophysics --- Mechanics --- Contractility (Biology) --- Biological models --- Biomathematics --- Biological systems --- Control theory --- Cybernetics --- Feedback control systems --- Nervous system --- Life sciences --- Biomass --- Life (Biology) --- Natural history --- Physical and Rehabilitation Medicine --- Biomechanic --- Biomecànica --- Models matemàtics --- Biologia --- Biomecànica. --- Models matemàtics. --- Biologia.
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As exciting as the new field of genomics is, it has not yet produced a basic conceptual change in biology. The fundamental problems remain: the origin of life, cell organization, the pathways of differentiation, aging, and the molecular and cellular capabilities of the brain. What has occurred is an explosion of molecular information obtained by genomic sequences, which will soon be followed by exhaustive catalogs of protein interactions and protein function. This wealth of information can be analyzed and manipulated only with the help of computers. The rapidly expanding role of computers in biology may usher in a profound conceptual change in how we study living systems in the laboratory. This book focuses on current computational approaches to understanding the complex networks of metabolic and gene regulatory capabilities of the cell. The contributors look well beyond the state of the art in computational biology to anticipate what biological research will be like in a post-genomic world.
Gene Expression Regulation --- Models, Genetic --- Metabolism --- Models, Biological --- Metabolic Phenomena --- Genetic Processes --- Phenomena and Processes --- Models, Theoretical --- Genetic Phenomena --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Genetics --- Biology --- Health & Biological Sciences --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Models, Mathematical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Metabolic Phenomenon --- Metabolic Process --- Metabolism Concepts --- Metabolism Phenomena --- Process, Metabolic --- Processes, Metabolic --- Anabolism --- Catabolism --- Metabolic Concepts --- Metabolic Processes --- Concept, Metabolic --- Concept, Metabolism --- Concepts, Metabolic --- Concepts, Metabolism --- Metabolic Concept --- Metabolism Concept --- Phenomena, Metabolic --- Phenomena, Metabolism --- Phenomenon, Metabolic --- Biological Model --- Biological Models --- Model, Biological --- Models, Biologic --- Biologic Model --- Biologic Models --- Model, Biologic --- Genetic Models --- Genetic Model --- Model, Genetic --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- Molecular Biology --- Computer Simulation --- Systems Theory --- RNAi Therapeutics --- Gene Regulatory Networks --- Molecular biology --- Mathematical models. --- BIOMEDICAL SCIENCES/Quantitative Biology --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Biomathematics
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Neurons in the brain communicate by short electrical pulses, the so-called action potentials or spikes. How can we understand the process of spike generation? How can we understand information transmission by neurons? What happens if thousands of neurons are coupled together in a seemingly random network? How does the network connectivity determine the activity patterns? And, vice versa, how does the spike activity influence the connectivity pattern? These questions are addressed in this 2002 introduction to spiking neurons aimed at those taking courses in computational neuroscience, theoretical biology, biophysics, or neural networks. The approach will suit students of physics, mathematics, or computer science; it will also be useful for biologists who are interested in mathematical modelling. The text is enhanced by many worked examples and illustrations. There are no mathematical prerequisites beyond what the audience would meet as undergraduates: more advanced techniques are introduced in an elementary, concrete fashion when needed.
Computational neuroscience. --- Neural networks (Neurobiology). --- Neurons. --- Neuroplasticity. --- Neurons --- Neuronal Plasticity --- Nerve Net --- Models, Neurological --- Nervous System Physiological Processes --- Models, Biological --- Nervous System --- Cells --- Models, Theoretical --- Anatomy --- Nervous System Physiological Phenomena --- Musculoskeletal and Neural Physiological Phenomena --- Investigative Techniques --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neuroscience --- Human Anatomy & Physiology --- Health & Biological Sciences --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Musculoskeletal and Neural Physiological Concepts --- Musculoskeletal and Neural Physiological Phenomenon --- Musculoskeletal and Neural Physiology --- Neural Networks (Anatomic) --- Nerve Nets --- Net, Nerve --- Nets, Nerve --- Network, Neural (Anatomic) --- Networks, Neural (Anatomic) --- Neural Network (Anatomic) --- Axon Pruning --- Axonal Pruning --- Dendrite Arborization --- Dendrite Pruning --- Dendritic Arborization --- Dendritic Pruning --- Dendritic Remodeling --- Neural Plasticity --- Neurite Pruning --- Neuronal Arborization --- Neuronal Network Remodeling --- Neuronal Pruning --- Neuronal Remodeling --- Neuroplasticity --- Synaptic Plasticity --- Synaptic Pruning --- Brain Plasticity --- Plasticity, Neuronal --- Arborization, Dendrite --- Arborization, Dendritic --- Arborization, Neuronal --- Arborizations, Dendrite --- Arborizations, Dendritic --- Arborizations, Neuronal --- Axon Prunings --- Axonal Prunings --- Brain Plasticities --- Dendrite Arborizations --- Dendrite Prunings --- Dendritic Arborizations --- Dendritic Prunings --- Dendritic Remodelings --- Network Remodeling, Neuronal --- Network Remodelings, Neuronal --- Neural Plasticities --- Neurite Prunings --- Neuronal Arborizations --- Neuronal Network Remodelings --- Neuronal Plasticities --- Neuronal Prunings --- Neuronal Remodelings --- Neuroplasticities --- Plasticities, Brain --- Plasticities, Neural --- Plasticities, Neuronal --- Plasticities, Synaptic --- Plasticity, Brain --- Plasticity, Neural --- Plasticity, Synaptic --- Pruning, Axon --- Pruning, Axonal --- Pruning, Dendrite --- Pruning, Dendritic --- Pruning, Neurite --- Pruning, Neuronal --- Pruning, Synaptic --- Prunings, Axon --- Prunings, Axonal --- Prunings, Dendrite --- Prunings, Dendritic --- Prunings, Neurite --- Prunings, Neuronal --- Prunings, Synaptic --- Remodeling, Dendritic --- Remodeling, Neuronal --- Remodeling, Neuronal Network --- Remodelings, Dendritic --- Remodelings, Neuronal --- Remodelings, Neuronal Network --- Synaptic Plasticities --- Synaptic Prunings --- Cell Plasticity --- Nervous System Physiological Concepts --- Nervous System Physiological Phenomenon --- Nervous System Physiological Process --- Physiology, Nervous System --- Nervous System Physiologic Processes --- Nervous System Physiology --- System Physiology, Nervous --- Anatomies --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Models, Mathematical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Computer Simulation --- Systems Theory --- Cell --- Cell Biology --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Biological Model --- Biological Models --- Model, Biological --- Models, Biologic --- Biologic Model --- Biologic Models --- Model, Biologic --- Model, Neurological --- Neurologic Model --- Neurological Model --- Neurological Models --- Neurologic Models --- Model, Neurologic --- Models, Neurologic --- Nerve Cells --- Cell, Nerve --- Cells, Nerve --- Nerve Cell --- Neuron --- physiology --- Computational neuroscience --- Neural networks (Neurobiology) --- 681.3*I51 --- Nervous system plasticity --- Neural adaptation --- Neural plasticity --- Neuronal adaptation --- Neuronal plasticity --- Plasticity, Nervous system --- Soft-wired nervous system --- Synaptic plasticity --- Adaptation (Physiology) --- Neurophysiology --- Developmental neurobiology --- Nerve cells --- Neurocytes --- Nervous system --- Biological neural networks --- Nets, Neural (Neurobiology) --- Networks, Neural (Neurobiology) --- Neural nets (Neurobiology) --- Cognitive neuroscience --- Neurobiology --- Neural circuitry --- Computational neurosciences --- Computational biology --- Neurosciences --- 681.3*I51 Models: deterministic; fuzzy set; geometric; statistical; structural (Patternrecognition) --- Models: deterministic; fuzzy set; geometric; statistical; structural (Patternrecognition)
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