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Bioprocess and biosystems engineering.
ISSN: 16157605 16157591 Year: 2001 Publisher: Heidelberg : Springer-Verlag,

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Bioseparations engineering : principles, practice, and economics
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ISBN: 0471244767 Year: 2001 Publisher: New York (N.Y.): Wiley

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Multidisciplinary resource for graduate studies and the biotechnology industryKnowledge of the genetic basis of biological functioning continues to grow at an astronomical rate, as do the challenges and opportunities of applying this information to the production of therapeutic compounds, specialty biochemicals, functional food ingredients, environmentally friendly biocatalysts, and new bioproducts from renewable resources. While genetic engineering of living organisms transforms the science of genomics into treatments for cancer, diabetes, and heart disease, or products for industry and agriculture, the science and technology of bioseparations are the keys to delivering these products in a purified form suitable for use by people.The methods, theory, and materials that reduce the science of bioseparations to practice, whether in the laboratory or the plant, are the subjects of Bioseparations Engineering. Examples address purification of biomolecules ranging from recombinant proteins to gene therapy products, with footnotes detailing economics of the products. Mechanistic analysis and engineering design methods are given for:* Isocratic and gradient chromatography* Sedimentation, centrifugation, and filtration* Membrane systems* Precipitation and crystallizationTopics addressed within this framework are: stationary phase selection; separations development; modeling of ion exchange, size exclusion, reversed phase, hydrophobic interaction, and affinity chromatography; the impact of regulatory issues on chromatography process design; organization of separation strategies into logical sequences of purification steps; and bridges between molecular biology, combinatorial methods, and separations science.A result of teaching and developing the subject matter over ten years, Bioseparations Engineering is an ideal text for graduate students, as well as a timely desk book for process engineers, process scientists, researchers, and research associates in the pharmaceuti

Biomedical communications : purposes, audiences, and strategies
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ISBN: 1281186619 9786611186616 0080528082 0124967515 9780124967519 9780080528083 Year: 2001 Publisher: San Diego, Calif. ; London : Academic,

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With data from the United States and Europe, Jon Miller and Linda Kimmel examine the public's understanding of and attitude toward biotechnology and biomedicine while they present methods of introducing cutting edge science to thenonscientist. Biomedical Communications illustrates how vital it is for researchers, journalists, and policy makers to clearly communicate their findings in a way that avoids general misconception or confusion. The authors explore how to acquire information about biomedical policy, discuss strategies for informing consumers, and present tactics for improvin

Enzymes in Nonaqueous Solvents : Methods and Protocols
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ISBN: 1592591124 9781592591121 128082087X 9786610820870 0896039293 Year: 2001 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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In recent years, enzymatic catalysis in organic solvents-as opposed to aqueous solutions-has gained considerable attention as a powerful new approach to the preparation of natural products, pharmaceuticals, fine chemicals, and food ingredients. In Enzymes in Nonaqueous Solvents: Methods and Protocols, leading chemists, biochemists, biotechnologists, and process engineers summarize for the first time a wide range of methods for executing enzymatic transformations under nonaqueous conditions. Each method includes detailed step-by-step instructions for its successful completion, a list of materials, and ancillary notes that explain the scientific basis of the procedure, as well as troubleshooting. Also provided are a generic description of key reactions, advice on biocatalyst preparation, discussion of reaction conditions, and instructions on bioreactor design. Comprehensive and state-of-the-art, Enzymes in Nonaqueous Solvents: Methods and Protocols offers today's synthetic chemists, biochemists, and process engineers all the essential information needed to carry out enzymatic reactions in nonaqueous media, as well as to successfully scale up to production quantities.

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