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The purpose of this book is to bring to interested readers (professionals and laypersons alike) an appreciation and a basic understanding of what the genetic code is and why it has come to revolutionize thinking about living systems as a whole. The consequences of this revolution in molecular biology are so vast as to be almost incomprehensible. It seems important in a democratic society to have a citizenry well informed about the crucial issues of the day, such as genetic engineering and molecular medicine, which impact the social order and the ethos of society in such a profound way. This bo

Genetics. --- Genetic code. --- Nucleotide sequence --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology)

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In 1951, the geneticist Luigi Luca Cavalli-Sforza was teaching in Parma when a student--a priest named Antonio Moroni--told him about rich church records of demography and marriages between relatives. After convincing the Church to open its records, Cavalli-Sforza, Moroni, and Gianna Zei embarked on a landmark study that would last fifty years and cover all of Italy. This book assembles and analyzes the team's research for the first time. Using blood testing as well as church records, the team investigated the frequency of consanguineous marriages and its use for estimating inbreeding and studying the relations between inbreeding and drift. They tested the importance of random genetic drift by studying population structure through demography of the last three centuries, using it to predict the spatial variation of frequencies of genetic markers. The authors find that drift-related genetic variation, including its stabilization by migration, is best predicted by computer simulation. They also analyze the usefulness and limits of the concept of deme for defining Mendelian populations. The genetic effect of consanguineous marriage on recessive genetic diseases and for the detection of dominance in metric characters are also studied. Ultimately bringing together the many strands of their massive project, Cavalli-Sforza, Moroni, and Zei are able to map genetic drift in all of Italy's approximately 8,000 communes and to demonstrate the relationship between each locality's drift and various ecological and demographic factors. In terms of both methods and findings, their accomplishment is tremendously important for understanding human social structure and the genetic effects of drift and inbreeding.

Consanguinity --- Inbreeding --- Human population genetics --- Human genetics --- Genetic variation in humans --- Variation (Biology) --- Population genetics --- Breeding --- Marriage --- Heredity --- Incest --- Kinship --- Variation. --- Prohibited degrees --- Frieseke, Frederick Carl

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genomes --- Génétique des populations --- Genetics (General) --- Genetics (General). --- Genetics --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- genetics --- genes --- genetic engineering --- population genetics --- Human genetics --- Molecular biology --- Genetics. --- Basic Sciences. Genetics --- Génétique

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"Discoveries in genetics are reported daily. Written for academic audiences and well-informed generalists, this authoritative and impressivly up-to-date 125-entry encyclopedia covers not only the basics and principles of genetics, but details the role of genetics in current issues, such as diseases, disorders, aging, sex, conservation, mapping, gene therapy, and food and nutrition."--"Outstanding Reference Sources," American Libraries, May 2002.

Genetics --- Génétique --- Encyclopedias --- Encyclopédies --- Genetique --- English --- 575 <03> --- 575 --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- General genetics. General cytogenetics. Immunogenetics. Evolution. Speciation. Phylogeny--Naslagwerken. Referentiewerken --- 575 <03> General genetics. General cytogenetics. Immunogenetics. Evolution. Speciation. Phylogeny--Naslagwerken. Referentiewerken --- Génétique --- Encyclopédies --- Genetics - Encyclopedias. --- Genetics - cncyclopedias - English --- Genetique - Encyclopedies

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In a book that promises to change the way we think and talk about genes and genetic determinism, Evelyn Fox Keller, one of our most gifted historians and philosophers of science, provides a powerful, profound analysis of the achievements of genetics and molecular biology in the twentieth century, the century of the gene. Not just a chronicle of biology’s progress from gene to genome in one hundred years, The Century of the Gene also calls our attention to the surprising ways these advances challenge the familiar picture of the gene most of us still entertain. Keller shows us that the very successes that have stirred our imagination have also radically undermined the primacy of the gene—word and object—as the core explanatory concept of heredity and development. She argues that we need a new vocabulary that includes concepts such as robustness, fidelity, and evolvability. But more than a new vocabulary, a new awareness is absolutely crucial: that understanding the components of a system (be they individual genes, proteins, or even molecules) may tell us little about the interactions among these components. With the Human Genome Project nearing its first and most publicized goal, biologists are coming to realize that they have reached not the end of biology but the beginning of a new era. Indeed, Keller predicts that in the new century we will witness another Cambrian era, this time in new forms of biological thought rather than in new forms of biological life.

Genetics --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- History --- History. --- Philosophy of science --- genetica (genen) --- moleculaire biologie --- génétique (gènes) --- biologie moléculaire --- 577.21 --- biologie --- evolutie --- genen --- genetica --- Human Genome Project --- prenatale diagnostiek --- recombinant DNA --- regulatie --- replicatie --- transcriptie --- translatie --- Genetics - History - 20th century