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A concise assessment of the risks to human health and the environment posed by exposure to chloral hydrate a chemical used in human and veterinary medicine as a sedative and hypnotic drug. Chloral hydrate and its metabolites are also formed as by-products when water is disinfected with chlorine. Release to the environment occurs from wastewater treatment facilities from the manufacture of pharmaceutical-grade chloral hydrate and from the waste stream during the manufacture of insecticides and herbicides that use chloral hydrate as an intermediate. For the general public the most important sour

Chloral -- Dose-response relationship. --- Chloral -- Environmental aspects. --- Chloral -- Toxicology. --- Dose-Response Relationship, Drug. --- Environmental Exposure. --- Health risk assessment. --- Risk Assessment. --- Environmental Pollution --- Epidemiologic Measurements --- Risk --- Risk Management --- Ethylene Glycols --- Pharmacological Phenomena --- Physiological Phenomena --- Glycols --- Public Health --- Probability --- Organization and Administration --- Statistics as Topic --- Environment and Public Health --- Health Services Administration --- Alcohols --- Phenomena and Processes --- Epidemiologic Methods --- Organic Chemicals --- Delivery of Health Care. --- Health Care Evaluation Mechanisms --- Quality of Health Care --- Chemicals and Drugs --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care Quality, Access, and Evaluation --- Risk Assessment --- Dose-Response Relationship, Drug --- Environmental Exposure --- Chloral Hydrate

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RNA-Ligand Interactions, Part B focuses on molecular biology methods. Major topics covered include: solution probe methods, tethered-probe methodologies, in vitro affinity selection methodologies, genetic methodologies for detecting RNA-protein interactions, protein engineering methodologies useful for RNA-protein interaction studies, and cell biology methods.RNA-Ligand Interactions, Part A, its companion, VOLUME 317 focuses on structural biology methods.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is o

Acide nucleique [Ribo] --- Acide ribonucléique --- Fixation protéique --- Ligand (Biochimie) --- Ligand binding (Biochemistry) --- Ligans (Biochemie) --- Protein binding --- Proteïnenbinding --- RNA (Nucleic acid) --- Ribonucleic acid --- Ribonucleïnezuur --- Ribose nucleic acid --- Zuur [Nucleine] [Ribo] --- Ligands (Biochemistry). --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Ligands. --- Models, Molecular. --- RNA. --- Structure-Activity Relationship. --- Ligands --- Structure-Activity Relationship --- RNA --- Models, Molecular --- Models, Theoretical --- Nucleic Acids --- Laboratory Chemicals --- Pharmacological Phenomena --- Biochemical Phenomena --- Nucleic Acids, Nucleotides, and Nucleosides --- Chemical Phenomena --- Specialty Uses of Chemicals --- Physiological Phenomena --- Investigative Techniques --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemicals and Drugs --- Chemical Actions and Uses --- Ligands (Biochemistry) --- Congresses --- Molecular dynamics --- Nucleic acids --- Ribose --- Biochemistry --- Nucleic acid structure --- Protein conformation --- Rna processes --- Probes (nucleic acid) --- Rna --- Rna binding proteins

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MEDICAL --- Health Care Delivery --- Managed care plans (Medical care) --- Emerging infectious diseases --- Insurance, Health --- Drug Resistance --- Patient Care Management --- Health Care Quality, Access, and Evaluation --- Public Health Practice --- Microbiological Phenomena --- Health Services Administration --- Insurance --- Phenomena and Processes --- Pharmacological Phenomena --- Public Health --- Health Care --- Environment and Public Health --- Financing, Organized --- Physiological Phenomena --- Economics --- Health Care Economics and Organizations --- Delivery of Health Care --- Drug Resistance, Microbial --- Communicable Disease Control --- Managed Care Programs --- Health & Biological Sciences --- Medical Care Plans --- Emerging infectious diseases. --- Managed care programs (Medical care) --- Managed care systems (Medical care) --- Managed health care --- Plans, Managed care (Medical care) --- Programs, Managed care (Medical care) --- Systems, Managed care (Medical care) --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Health insurance --- Medical care --- Communicable diseases