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In Vitro Neurochemical Techniques is the third work updating and expanding the best-selling inaugural volume of Humana Press's warmly received Neuromethods series, General Neurochemical Techniques (vol. 1). The key techniques detailed in this new edition encompass the breadth of neurochemical and molecular neurobiology research, ranging from the isolation of neuronal genes and the study of their expression to the analysis of receptor-ligand interactions, to the characterization of the consequences of receptor activation. The methods include electrophysiological techniques to explore the functional properties of receptors present in the membranes of excitable cells, methods to isolate novel genes central to neurobiological processes, and protocols to perform in situ hybridization histochemistry. Other methods cover the measurement of changes in gene expression, the rapid identification of gene polymorphisms, and the identification and characterization of second messenger pathways. The companion volumes, In Vivo Neuromethods and Cell Neurobiology Techniques, cover both in vivo methods and in vitro cell neurobiology approaches. Like the original, all three cutting-edge works will prove exceptionally useful to those basic and clinical neuroscientists who want to expand the range of their current research or develop competence in complementary methods.

Neurosciences. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system

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In Neurodegeneration Methods and Protocols, Jean Harry and Hugh Tilson bring together a collection of detailed, state-of-the-art techniques for studying many aspects of nervous system cell biology. The methods span a multidisciplinary range of cellular and molecular approaches to both normal and injured nervous system function, and particularly to neurodegenerative processes. Included are basic RT-PCR techniques, cell culture systems, second-messenger signaling methods, and patch-clamp techniques. Cutting-edge and authoritative, Neurodegeneration Methods and Protocols will illuminate nervous system function, injury, degeneration, and the repair/regenerative process. These powerful techniques will also allow established laboratories-both experimental and clinical-to expand their array of methods for solving research problems and help utilize multidisciplinary procedures beyond their experience.

Neurosciences. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system

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Nervous system --- Neurologic examination --- Diagnostic Techniques, Neurological --- Nervous System Diseases --- Neuropsychological Tests --- Diseases --- Diagnosis --- diagnosis

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The underlying theme of this book the role of experience in the development of the nervous system. It is now widely acknowledged that there are a variety of organi- environment interactions that guide the development of the nervous system. The popular press has also picked up on this theme and parents are being advised to enrich their child's sensory experience as early as possible. The importance of experience in development is so well accepted that it has begun to dictate public policy. In 1997, the President and First Lady hosted "The White House Conference on Early Childhood Development and Learning: What New Research on the Brain Tells Us About Our Youngest Children. " Along with this conference came a reemphasis on programs directed at enriching the en- ronment of America's youth. In some cases laws have been passed to assure enhanced early experience. In Georgia, the former governor proposed sending newborn children home from the hospital with classical music CDs. This received some praise, but was also ridiculed by others who felt the policy was not justified by the available scientific evidence. Here in Florida, enhanced "brain development activities" are mandated for sta- funded child care facilities. Chapter 402. 25 of the 1998 State of Florida Statues reads (emphasis added): Infants and toddlers in state-funded education and care programs; brain development activities.

Developmental neurobiology --- Neurobiology --- Neurology. --- Neurosciences. --- Neurology . --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Medicine --- Neuropsychiatry --- Diseases

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Nervous System Physiological Phenomena. --- Nervous System Diseases. --- Neurochemistry. --- Neurochimie --- Nervous System Physiological Concepts --- Nervous System Physiological Phenomenon --- Physiology, Nervous System --- Nervous System Physiology --- System Physiology, Nervous --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Nervous System Physiology. --- Nervous System Physiological Process --- Nervous System Physiologic Processes --- Neurochemistry --- Nervous System Diseases --- Nervous System Physiological Phenomena --- Nervous System Physiological Processes --- Nervous System --- Neurology --- Biochemistry --- Neurosciences --- Neurochemistries --- Chemistry --- physiology --- Neuropathology --- Human biochemistry --- Diseases --- Musculoskeletal and Neural Physiological Phenomena --- Biological Science Disciplines --- Phenomena and Processes --- Natural Science Disciplines --- Disciplines and Occupations --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- chemistry.