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Cellular signal transduction --- Serotonin --- Congresses. --- Receptors --- Congresses
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Water-Electrolyte Balance --- Cell Size --- Signal Transduction
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Cellular signal transduction --- Cell receptors --- Biological control systems --- Signal Transduction --- Cell Communication --- Receptors, Cell Surface
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Human physiology --- Calcium channels. --- Calcium --- Cellular signal transduction. --- Physiological effect.
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Cellular signal transduction --- Gangliosides --- Neurochemistry --- Sphingolipids --- Nervous System --- Signal Transduction --- Congresses. --- Physiological effect --- Conferences - Meetings --- Lipids --- Sphingosine --- Glycosphingolipids --- Congresses --- Physiological effect&delete&
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Signal Transduction --- Insulin --- Glycogen --- Adipocytes --- Deoxyglucose --- physiology --- pharmacology --- biosynthesis --- metabolism --- metabolism
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Affective Disorders --- Affective Disorders --- Affective disorders --- Antidepressants --- Antidepressive Agents --- Cellular signal transduction --- Neural transmission --- Signal Transduction --- Drug therapy --- Congresses. --- Physiopathology --- Congresses. --- Pathophysiology --- Congresses. --- Mechanism of action --- Congresses. --- Pharmacology --- Congresses. --- Congresses. --- Congresses. --- Drug effects --- Congresses.
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Biological techniques --- General biophysics --- Histology. Cytology --- Cellular signal transduction --- Cytology --- Transduction du signal cellulaire --- Cytologie --- Laboratory manuals. --- Manuels de laboratoire
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Most lymphocytes recirculate throughout the body, migrating from blood through organized lymphoid tissues such as lymph nodes (LN) and Peyer's patches (PP), then to lymph and back to blood (GOWANS and KNIGHT 1964). Smaller numbers of lymphocytes migrate from blood to extranodal tissues such as pancreas and then through lymphatic vessels to LN (MACKAY et al. 1990). An important feature of this migration is the ability of lymphocytes to recognize and adhere to the surface of blood vessel endothelial cells before migrating through the vessel wall into surrounding tissue (CARLOS and HARLAN 1994; IMHOF and DUNON 1995; BUTCHER and PICKER 1996). Adhesion interactions of vascular endothelium with lymphocytes under flow or shear consist of at least four steps: (I) an initial transient sticking or rolling; (2) if the lymphocytes encounter appropriate activating or chemotactic factors in the local environment, rolling may be followed by a lymphocyte activation step that then leads to; (3) strong adhesion or sticking that may be followed by; (4) lym phocyte diapedesis into tissue (BUTCHER 1991; SHIMUZU et al. 1992; SPRINGER 1994; BARGATZE et al. 1995). Specific lymphocyte and endothelial adhesion molecules (AM) are involved in each step of this "adhesion cascade" (reviewed in CARLOS and HARLAN 1994; IMHOF and DUNON 1995; BUTCHER and PICKER 1996). This allows lymphocyte migration to be controlled at several different steps, leading to a combinatorial increase in specificity and sensitivity.
Integrins --- Leucocytes --- Leukocyten --- Leukocytes --- White blood cells --- White cells --- Signal Transduction --- immunology --- Signal Transduction. --- immunology. --- Immunology. --- Cancer --- Immunological aspects --- Cell biology. --- Cancer research. --- Cell Biology. --- Cancer Research. --- Cancer research --- Cell biology --- Cellular biology --- Biology --- Cells --- Immunobiology --- Life sciences --- Serology --- Cellular signal transduction. --- Immunocompetent cells. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Immunologically competent cells --- Immune system
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Transmembrane Signaling Protocols brings together a collection of practical, cutting-edge techniques for the study of cell signaling. Written by acknowledged leaders in the field, the protocols provide detailed, step-by-step instructions, helpful notes, and troubleshooting tips that make even the most powerful of the latest techniques readily reproducible. The protocols presented include the use of peptide libraries to study transmembrane signaling; the use of single-cell assays to analyze signal transduction pathways; the reconstitution of signaling complexes; methods for analyzing protein-protein interactions, and more. Introductory reviews explain the basic theory and enable researchers new to the area to rapidly gain understanding, as well as command of the practical knowledge and expertise afforded by the protocols. The time-tested techniques collected in Transmembrane Signaling Protocols make available to all researchers the many state-of-the-art techniques that have recently led to landmark discoveries in transmembrane signaling. The book is destined to become a standard resource for both conceptual information and the practical detail needed to carry out and interpret laboratory procedures in this dramatically advancing field.
SCIENCE --- Life Sciences / Biochemistry --- Cellular signal transduction --- Signal Transduction --- Biochemical Processes --- Cell Physiological Processes --- Cell Physiological Phenomena --- Chemical Processes --- Biochemical Phenomena --- Chemical Phenomena --- Phenomena and Processes --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Laboratory manuals --- Laboratory manuals. --- Cellular control mechanisms --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Information theory in biology --- Cell regulation --- Biological control systems --- Cell metabolism --- Cytology. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- CELLULAR SIGNAL TRANSDUCTION --- LABORATORY MANUALS
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