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Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors.
Cancer --- Immunological aspects. --- Carcinogenesis --- Immunological aspects --- Interleukin-1 --- Neoplasms --- Immunotherapy --- Tumor Microenvironment --- Immunology. --- immunology --- Interleukin-1. --- Immunotherapy. --- Tumor Microenvironment. --- immunology.
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Role of Tumor Microenvironment in Breast Cancer and Targeted Therapies discusses the current understanding of breast cancer tumor microenvironment components, their role in tumorigenicity and the development of therapeutic resistance, along with updates on recent advances. Presents up-to-date knowledge on the interplays of stromal components surrounding breast tumor cells. Explores recent advances and trends in the molecular mechanisms of breast tumorigenesis and how to explore further molecular targets.
Breast --- Cancer --- Treatment. --- Drug targeting. --- Breast Neoplasms --- Tumor Microenvironment --- Drug Delivery Systems --- Drug Development --- Tumors. --- Breast Neoplasms. --- Tumor Microenvironment. --- Drug Delivery Systems. --- Drug Development.
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"Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters."--
Host-bacteria relationships. --- Bacteria-host relationships --- Relationships, Host-bacteria --- Host-parasite relationships --- Immune system. --- Microbial ecology. --- Cancer --- Host Microbial Interactions --- Microbiota --- Tumor Microenvironment --- Immunological aspects. --- immunology --- Host Microbial Interactions. --- Tumor Microenvironment. --- immunology.
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"Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches."--
Gas reservoirs. --- Gas pools --- Natural gas reservoirs --- Pools, Gas --- Reservoirs, Gas --- Hydrocarbon reservoirs --- Natural gas --- Geology --- Breast --- Cancer --- Treatment. --- Cancer. --- Drug targeting. --- Breast Neoplasms --- Nanoparticle Drug Delivery System --- Tumor Microenvironment --- Chemotherapy. --- drug therapy --- Nanoparticle Drug Delivery System. --- Tumor Microenvironment. --- drug therapy.
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oncology --- urological oncological diseases --- cancer biomarkers --- cancer therapy --- molecular tumor pathology --- tumor microenvironment --- Oncology --- Carcinogenesis --- Oncology. --- Cancer --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Pathology --- Genetic toxicology --- Molecular carcinogenesis --- Pathology, Molecular --- Tumors --- Molecular aspects --- Molecular aspects. --- Pathogenesis
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Lymphatic Metastasis. --- Neoplasm Metastasis. --- Tumor Microenvironment. --- Carcinogenesis. --- Oncogenesis --- Tumorigenesis --- Carcinogeneses --- Oncogeneses --- Tumorigeneses --- Cancer Microenvironment --- Cancer Microenvironments --- Microenvironment, Cancer --- Microenvironment, Tumor --- Microenvironments, Cancer --- Microenvironments, Tumor --- Tumor Microenvironments --- Metastases, Neoplasm --- Metastasis, Neoplasm --- Neoplasm Metastases --- Metastase --- Metastasis --- Metastases --- Neoplasms --- Lymph Node Metastasis --- Lymph Node Metastases --- Lymphatic Metastases --- Metastasis, Lymph Node --- Sentinel Lymph Node --- Sentinel Lymph Node Biopsy --- secondary --- Lymphatics. --- Metastasis. --- Cancer. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Cancer --- Cancer metastasis --- Dissemination of cancer --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Lymphatic system --- Immune system --- Dissemination
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