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Organomagnesium methods in organic synthesis
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ISBN: 0127309454 9786611033750 1281033758 0080538177 9780127309453 9780080538174 Year: 1995 Publisher: London San Diego Academic Press

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Abstract

The book opens with a general overview of the constitution and reactivity of organomagnesium compounds, followed by information on handling them and on their detection and estimation. Throughout, practical aspects aswell as principles are emphasized.The chapters on the synthesis of organomagnesium compounds cover the preparation of special forms of metallic magnesium and the reaction of magnesium with substrates such as dienes, as well as the traditional preparation of Grignard reagents. Preparations by metallation and metal-halogen exchanges are also included, as are newer methods such as


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Grignard Reagents and Transition Metal Catalysts.
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ISBN: 1523116420 3110383438 3110352729 9783110352665 3110352664 9783110352726 3110352737 Year: 2016 Publisher: De Gruyter

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Abstract

In 1912, the Chemistry Nobel Prize was awarded for the discovery of the so-called Grignard reagents. Nowadays, many transition metal variants are developed to modify reactivity and selectivity of the C-C bond formation reaction. The Grignard reaction is one of the fundamental organometallic reactions, often used in alcohol syntheses. With transition metals like iron, cobalt and nickel or with noble metals like copper, silver and palladium, modern Grignard reagents can be designed in reactivity, selectivity and functional group tolerance. This book, written by international experts, presents an overview on timely Grignard chemistry involving transition metals.

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