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Pathophysiology is the convergence of pathology (the discipline of observed changes in a diseased state) with physiology (the mechanisms of systems operation). It represents the functional changes that occur because of injury or disease. This volume provides state-of-the-art up-to-date literature reviews on pathophysiological processes in a number of disease states. The book is organised methodically in a head-to-toe systems approach examining aspects of neuropathophysiology, endocrine pathophysiology, structural biology, renal pathophysiology and genitourinary pathophysiology. This short volume on pathophysiology is intended for general medical and biomedical students at both undergraduate and postgraduate levels. In addition, it is a useful short update of recent advances in research and translational biology to those working in academia or healthcare science.
Physiology, Pathological. --- Clinical physiology --- Pathological physiology --- Pathophysiology --- Physiopathology --- Pathology --- Physiology --- Medicine --- Health Sciences
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Venous Thromboembolism remains a major health challenge in many countries because of the morbidity and mortality it inflicts, mainly in hospitalized patients. This book, with contributions from distinguished experts in the field, depicts some hot aspects on aetilogics of VTE, the disease burden in neonates, renal disease and cancer patients as well as issues relevant to prophylaxis and the concept of VTE as patient injury content.
Physiology, Pathological. --- Clinical physiology --- Pathological physiology --- Pathophysiology --- Physiopathology --- Pathology --- Physiology --- Oncology
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Arteries --- Artères --- physiology --- Periodicals. --- physiopathology --- Physiology --- Periodicals --- Pathophysiology --- Diseases --- Physiologie --- Périodiques --- Physiopathologie --- Maladies --- Treatment --- physiology. --- physiopathology. --- Health Sciences --- Anatomy --- Artery --- Diseases. --- Pathophysiology. --- Blood-vessels --- athophysiology --- epidemiology --- treatment of arterial structure and function
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Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur, new possibilities emerge for limiting the effects of aging on neural function. A single source reference is necessary to keep abreast of the recent advances and future directions of gerontology research. Brain Aging: Models, Methods, and
Aging --- Brain --- Cognition --- Nerve Degeneration. --- physiology. --- Aging. --- physiopathology. --- Pathophysiopathology. --- Cerebrum --- Mind --- Central nervous system --- Head --- Brein --- Bejaarden --- Hersenen --- Biologie --- Biochemie --- Oudere --- Gemeenschap --- School --- Buurt
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Neurological and psychiatric disorders can occur in endocrine diseases either in the setting of the clinical manifestations of the same (i.e., hyper- or hyposecretion of hormones or peptides from the endocrine glands) or as events secondary to the pathogenetic mechanisms of the endocrinopathy (i.e., autommunity affecting endocrine glands and the brain). Also the medical or surgical treatment of the endocrine disease can sometimes determine the occurrence of neurological or psychiatric abnormalities. Moreover some genetic alterations can lead to syndromes affecting both the endocrine and the nervous system with a variety of possible manifestations. In the last couple of decades a number of associations between dysfunctions of the endocrine system and neurological or psychiatric manifestations have appeared and only in the minority of the cases this link has been fully elucidated. Often the neurological or psychiatric alterations still represent a relevant challenge for clinicians with regard to the management of the patients. The complexity of the topic and the limited availability of laboratory research models for the study of the endocrine system-nervous system cross-interaction are making the scientific progresses intricate and, sometimes, slow. A dedicated focus to such broad and often still obscure topic might help and clarify the current state-of-the-art in the field and direct the goals of future research.
Neuroendocrinology. --- Psychoneuroendocrinology. --- Neuropsychiatry. --- Endocrine System Diseases --- physiopathology. --- Eating Disorders --- Polycystic Ovary Syndrome --- Obesity --- Exercise --- gender identity --- Acromegaly --- Quality of Life --- Cushing Syndrome --- Thyroid Surgery --- Hypogonadism
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The basal ganglia has received much attention over the last two decades, as it has been implicated in many neurological and psychiatric disorders. Most of this research—in both animals and humans—attempt to understand the neural and biochemical substrates of basic motor and learning processes, and how these are affected in human patients as well as animal models of brain disorders. The current volume contains research articles and reviews describing basic, pre-clinical and clinical neuroscience research of the basal ganglia written by attendees of the 11th Triennial Meeting of the International Basal Ganglia Society (IBAGS) that was held March 3-7th, 2013 at the Princess Hotel, Eilat, Israel and by researchers of the basal ganglia. Specifically, articles in this volume include research reports on the biochemistry, computational theory, anatomy and physiology of single neurons and functional circuitry of the basal ganglia networks as well as the latest data on animal models of basal ganglia dysfunction and clinical studies in human patients.
Basal ganglia --- Computational neuroscience --- Neurobiology --- Basal Ganglia --- Physiology. --- Research. --- Mathematical models. --- physiopathology. --- Subthalamic Nucleus --- dopaime --- Parkinson's disease (PD) --- human imagine studies --- animal studies --- computational modeling
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Cardiology --- Clinical trials --- Cardiovascular Diseases --- Cardiologie --- Etudes cliniques --- Periodicals --- therapy --- Periodicals. --- physiopathology --- Périodiques --- Cardiology. --- Clinical trials. --- therapy. --- physiopathology. --- Controlled clinical trials --- Patient trials of new treatments --- Randomized clinical trials --- Trials, Clinical --- Clinical medicine --- Human experimentation in medicine --- Heart --- Internal medicine --- Research --- Diseases
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Retina --- Vitreous Body --- Retinal Diseases --- Vitreoretinal Surgery --- Vitreous body --- Rétine --- Corps vitré --- physiopathology --- Periodicals --- Diseases --- Périodiques --- Maladies --- Chirurgie --- Retinal Diseases. --- Vitreoretinal Surgery. --- physiopathology. --- Diseases. --- Vitreous humor --- Surgeries, Vitreoretinal --- Surgery, Vitreoretinal --- Vitreoretinal Surgeries --- Disease, Retinal --- Diseases, Retinal --- Retinal Disease --- Corpus vitreum --- Vitreum --- opthalmics --- vitreoretinal disorders --- Color Vision Defects --- Posterior segment (Eye) --- vitreoretinal disorders --- ophthalmics --- Ophthalmology
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Cardiovascular disease is ranked as the leading cause of death world wide, responsible for 17.1 million deaths globally each year. Such numbers are often difficult to comprehend. Heart disease kills one person every 34 seconds in the USA alone. Although the leading killer, the incidence of cardiovascular disease has declined in recent years due to a better understanding of the pathology, implementation of lipid lowering therapy new drug regimens including low molecular weight heparin and antiplatelet drugs such as glycoprotein IIb/IIIa receptor inhibitors and acute surgical intervention. The disease burden has a great financial impact on global healthcare systems and major economic consequences for world economies. This text aims to deliver the current understanding of coronary artery disease and is split into three main sections: 1. Epidemiology and pathophysiology of coronary artery disease 2. Coronary artery disease diagnostics and 3. Treatment regimens for coronary artery disease
Coronary heart disease. --- Epidemiology. --- Physiology, Pathological. --- Clinical physiology --- Pathological physiology --- Pathophysiology --- Physiopathology --- Pathology --- Physiology --- Diseases --- Public health --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Heart --- Type A behavior --- Cardiovascular medicine
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This Research Topic aims to update the knowledge on neuropsychology and neuropsychiatry in neurodegenerative disorders . A special interest is placed on providing a thorough understanding of underlying brain damage in a range of neurodegenerative disorders (such as Parkinson's and Alzheimer's diseases, among many others), as well as their behavioral consequences. Studies on both neuropsychological and neuropsychiatric disturbances of neurodegenerative disorders will be covered; including description of new tests, correlation of findings with biomarkers and correlation of findings with neuropathology, as well as the implication of neuropsychological and neuropsychiatric research in therapeutic techniques and potential interventions.
Nervous system --- Geriatric neuropsychiatry. --- Nervous System Diseases --- Degeneration --- Physiopathology. --- Diseases. --- Research. --- Aged. --- Parkinson Disease --- Neuroimaging --- Neuropsychological Tests --- Neurodegenerative Diseases --- Neuropsychiatry --- graph theory --- Neuropsychology --- Mild Cognitive Impairment --- Alzheimer Disease --- Emotions
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