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Meningitis is a medical emergency requiring a rapid diagnosis and an immediate transfer to an institution supplied with appropriate antibiotic and supportive measures. This book aims to provide general practitioners, paediatricians, and specialist physicians with an essential text written in an accessible language, and also to highlight the differences in pathogenesis and causative agents of meningitis in the developed and the developing world.

Meningitis. --- Leptomeningitis --- Central nervous system --- Neisseria meningitidis --- Diseases --- Infectious & contagious diseases

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This timely collection of expert papers draws attention to the global burden of meningitis and the challenges faced by the WHO’s roadmap to defeat meningitis by 2030. The three main goals of the meningitis roadmap are to eliminate epidemics of bacterial meningitis, reduce cases and deaths from vaccine-preventable bacterial meningitis, and reduce disability and improve quality of life after meningitis of any cause. This book includes a wide range of original research and reviews on epidemiology and vaccination of bacterial meningitis that have direct relevance to advancing the goals of the roadmap.

meningitis --- child mortality --- neonatal sepsis --- global health --- global health estimates --- modelling --- Streptococcus pneumoniae --- Haemophilus influenzae --- Neisseria meningitidis --- bacterial meningitis --- S. pneumoniae --- N. meningitidis --- H. influenzae --- S. agalactiae --- conjugate vaccines --- post-vaccine surveillance --- vaccine --- Africa --- mathematical modelling --- susceptibility --- invasive bacterial infections --- complement --- genetic factors --- Streptococcus agalactiae --- group B streptococci --- capsule --- meningococcal group --- nongroupable --- meningococcal carriage --- invasive meningococcal disease --- meningococcal urethritis --- neonatal infections --- epidemiology --- antibiotic resistance --- etiologic diagnosis --- enterovirus --- group B Streptococcus --- neurological sequelae --- hearing loss --- seizure --- epilepsy --- hydrocephalus --- focal neurological deficit --- corticosteroid --- dexamethasone --- invasive pneumococcal disease --- pneumococcal conjugate vaccines --- serotypes --- vaccine impact --- pneumococcal meningitis --- serotype distribution --- PCV impact --- global --- meta-analysis --- surveillance --- meningococcus --- pneumococcus --- Hib --- group B streptococcus --- conjugate vaccine --- rapid diagnostic test --- national reference laboratory --- cerebrospinal fluid --- Niger --- Burkina Faso --- tuberculosis --- tuberculous meningitis --- TBM --- children --- impact of Hib conjugate vaccine --- Hia --- NTHi --- burden --- social and economic costs --- WHO meningitis roadmap --- disability --- n/a