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This reprint focuses on the transcatheter treatment of the main structural heart diseases covering the latest innovations and hot topics on this subject. All the technological developments witnessed in recent decades have made structural heart disease interventions a growing field and have contributed to offering patients less invasive, more effective, and safe alternative approaches.
Medicine --- Cardiovascular medicine --- cerebral protection device --- transcatheter aortic valve replacement --- stroke --- cerebrovascular events --- bovine aortic arch --- TAVR --- percutaneous access --- vascular complications --- surgical cut-down --- transfemoral approach --- aortic stenosis --- transcatheter aortic valve implantation --- valvular heart disease --- congestion --- plasma volume --- risk stratification --- TAVI --- SAVR --- young --- balloon aortic valvuloplasty --- bridge therapy --- destination therapy --- heart failure --- transradial coronaro-angiography --- single-catheter technique --- coronary artery disease --- futility --- transfemoral --- transcatheter --- aortic valve --- vascular --- complications --- BASILICA --- coronary artery obstruction --- structural heart intervention --- transcatheter mitral valve replacement --- mitral regurgitation --- transoesophageal echocardiography --- cardiac computed tomography --- TAVI degeneration --- SAVR after TAVI --- long-term outcome of TAVI --- tricuspid regurgitation --- atrial functional tricuspid regurgitation --- transcatheter tricuspid valve interventions --- echocardiography --- three-dimensional echocardiography --- multimodality imaging --- sizing --- planning --- MDCT --- 3D echocardiography --- MRI --- n/a
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Advanced experimental and computational biomechanics have become essential components to better understand the physiological and pathological conditions of biological tissues in the human body. Recent advances in medical imaging modalities, image segmentation, tissue characterization experiments, and predictive computer simulations have made major contributions to transforming current therapeutic paradigms, towards the facilitation of patient-specific diagnostics and individualized surgery planning. This Special Issue of Bioengineering on Advances in Biological Tissue Biomechanics, therefore, focuses on research dealing with cutting-edge experimental and computational methodologies for biomechanical investigations of tissues in the human body system across multiple spatial and temporal scales.
computational fluid dynamics --- bileaflet mechanical heart valve --- adverse hemodynamics --- transvalvular pressure gradients --- turbulent shear stresses --- blood damage --- platelet activation --- aortic valve --- calcification --- elastin degradation --- leaflet --- curvature --- biomarker --- early detection --- porcine brain --- mechanical behavior --- hydration effects --- Split-Hopkinson pressure bar --- micromechanics --- finite element analysis --- collagen crimp --- elastin --- microstructures --- force-controlled mechanical testing --- the tricuspid valve --- functional tricuspid regurgitation --- cardiovascular imaging --- mechanical characterization --- in-vitro experiments --- constitutive modeling --- geometrical modeling --- finite element modeling --- isogeometric analysis (IGA) --- biaxial mechanical characterization --- fluid-structure interactions --- material anisotropy --- sub-valvular components --- soft tissue --- liver --- high-rate compression --- polymeric split-Hopkinson pressure bar --- pentagalloyl glucose --- aneurysm --- enzyme --- biomechanics --- aorta --- biaxial mechanical testing --- cardiac valves --- osmotic swelling --- parameter estimation --- nonlinear preconditioning --- gradient-based minimization --- cirrus --- myocardium --- stiffness --- viscoelastic property --- anisotropy --- fibrosis --- the mitral valve --- collagen fiber architecture --- glycosaminoglycan --- uniaxial mechanical testing --- in-vitro flow loops --- polarized spatial frequency domain imaging --- tricuspid regurgitation --- spatial alignment --- collagen fiber reorientation --- in vivo stress/strain quantification --- constitutive models --- soft tissues --- growth and remodeling (G & R) --- multiscale biomechanics --- patient-specific modeling
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