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Fluorides --- Fluorures --- physiology --- Periodicals. --- toxicology --- Physiological effect --- Periodicals --- Toxicology --- Effets physiologiques --- Périodiques --- Toxicologie --- Physiological effect. --- Toxicology. --- Health Sciences --- Physiology --- fluoride toxicology --- fluoride biochemistry --- veterinary aspects of fluoride --- clinical aspects of fluoride --- agricultural aspects of fluoride --- dental aspects of fluoride --- Fluorides. --- Fluorine compounds --- Halides --- Fluoride --- Stomatology
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This report deals with 2 4 6-tribromophenol (2 4 6-TBP) and other simple brominated phenols with a single benzene ring. However information on toxicity ecotoxicity and environmental fate on bromophenols other than 2 4 6-TBP is very limited. On the basis of the very limited data on concentrations of bromophenols in waters and sediment the present risk to aquatic organisms from 2 4 6-TBP in sediment would appear to be low. Insufficient data are available to make a meaningful risk assessment for other brominated phenols and for all brominated phenols in the terrestrial environment.
Fluorine. --- Nitration. --- Phenols. --- Environmental Pollution --- Risk --- Inorganic Chemicals --- Risk Management --- Organic Chemicals --- Epidemiologic Measurements --- Organization and Administration --- Chemicals and Drugs --- Probability --- Public Health --- Health Services Administration --- Statistics as Topic --- Environment and Public Health --- Epidemiologic Methods --- Health Care --- Health Care Evaluation Mechanisms --- Quality of Health Care --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care Quality, Access, and Evaluation --- Risk Assessment --- Phenols --- Environmental Exposure --- Bromine Compounds
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Three of the eleven papers focused on groundwater recharge and its impacts on the groundwater regime, in which recharge was caused by riverbed leakage from river ecological restoration (artificial water replenishment). The issues of the hydrogeological parameters involved (such as the influence radius) were also reconsidered. Six papers focused on the impact of river ecological replenishment and other human activities on river and watershed ecology, and on groundwater quality and use function. The issues of ecological security at the watershed scale and deterioration of groundwater quality were of particular concern. Two papers focused on water resources carrying capacity and water resources reallocation at the regional scale, in the context of the fact that ecological water demand has been a significant topic of concern. The use of unconventional water resources such as brackish water has been emphasized in the research in this issue.
influence radius --- Dupuit --- Thiem --- groundwater flow system --- sustainable development --- hydrogeochemistry --- ionic ratios --- factor analysis --- inverse modeling --- Yangtze River --- water resources carrying capacity --- uncertainty analysis --- fuzzy comprehensive evaluation model --- weight sensitivity analysis --- Yongding River --- groundwater numerical simulation --- artificial ecological water supplement --- groundwater recharge resources amount evaluation --- alga control --- typical biological chain --- Ecopath model --- ecological restoration --- Lianshi Lake --- Songnen Plain --- groundwater --- fluorine --- distribution --- formation --- human health risk --- groundwater quality --- groundwater hydrochemistry --- drinking suitability --- irrigation suitability --- health risk assessment --- watershed ecological security assessment --- DPSIR model framework --- environmental management --- water allocation --- brackish water --- general algebraic modeling system --- water diversion project --- numerical simulation --- MODFLOW --- n/a
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Around the globe dental caries is a public health problem and the disease burden is particularly high among under-privileged groups. In several low-income countries the WHO anticipates that the incidence of dental caries will increase as a result of growing consumption of sugars and inadequate exposure to fluorides. The good news is that dental caries is preventable through the effective use of fluoride. WHO emphasizes the importance of automatic administration of fluoride as part of public health programmes. Substantial research has provided evidence of the effectiveness of milk fluoridation
Dental Caries -- prevention & control. --- Dental caries -- Prevention. --- Fluoridation. --- Dental caries --- Milk --- Water Supply --- Tooth Demineralization --- Beverages --- Preventive Dentistry --- Public Health Dentistry --- Anions --- Hydrofluoric Acid --- Dairy Products --- Bodily Secretions --- Environment and Public Health --- Fluorine Compounds --- Food and Beverages --- Sanitary Engineering --- Ions --- Food --- Tooth Diseases --- Dentistry --- Fluids and Secretions --- Electrolytes --- Sanitation --- Stomatognathic Diseases --- Inorganic Chemicals --- Technology, Industry, Agriculture --- Health Care --- Anatomy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Public Health --- Chemicals and Drugs --- Diseases --- Fluoridation --- Dental Caries --- Fluorides --- Health & Biological Sciences --- Dentistry - General --- Prevention --- Fluoride --- Carious Dentin --- Decay, Dental --- Dental White Spot --- White Spot, Dental --- White Spots, Dental --- Caries, Dental --- Dental Decay --- Dental White Spots --- White Spots --- Carious Dentins --- Dentin, Carious --- Dentins, Carious --- Spot, White --- Spots, White --- White Spot --- Water Fluoridation --- Fluoridation, Water --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Public --- Anatomies --- Beverages and Food --- Compounds, Fluorine --- Dairy Product --- Product, Dairy --- Products, Dairy --- Fluoridation of milk --- Supplies, Water --- Supply, Water --- Water Supplies --- Water --- Demineralization, Tooth --- Hypomineralization, Tooth --- Tooth Hypomineralization --- Hypomineralizations, Tooth --- Tooth Hypomineralizations --- Dentistry, Public Health --- Dentistries, Preventive --- Dentistry, Preventive --- Preventive Dentistries --- Beverage --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Chemicals, Inorganic --- Mouth and Tooth Diseases --- Dental Diseases --- Dental Disease --- Disease, Dental --- Disease, Stomatognathic --- Diseases, Dental --- Diseases, Stomatognathic --- Stomatognathic Disease --- Disease, Tooth --- Diseases, Tooth --- Tooth Disease --- Nutrients --- Foods --- Plumbing --- Engineering, Sanitary --- supply & distribution --- Secretions --- Bodily Secretion --- Secretion --- Secretion, Bodily --- Secretions, Bodily --- Fluohydric Acid --- Fluorhydric Acid --- Hydrogen Fluoride --- Acid, Fluohydric --- Acid, Fluorhydric --- Acid, Hydrofluoric --- Fluoride, Hydrogen --- Secretions and Fluids --- Infant Nutritional Physiological Phenomena --- Lactation --- Cariostatic Agents --- Community Health --- Health, Community --- Preventive Medicine --- Education, Public Health Professional --- Fluorine --- Preventive dentistry --- Teeth --- Conservation of Water Resources --- Groundwater --- Decalcification, Pathologic --- Preventive Health Services --- Primary Prevention --- Potassium Magnesium Aspartate --- Oral Medicine --- Nutrient --- Nutritional Physiological Phenomena --- Nutritional Requirements --- Physiological effect --- Care and hygiene --- Milk Fluoridation --- Salt Fluoridation --- Fluoridation, Milk --- Fluoridation, Salt --- Carious Lesions --- Carious Lesion --- Lesion, Carious --- Lesions, Carious --- Spot, Dental White --- Spots, Dental White --- Cow Milk --- Cow's Milk --- Milk, Cow --- Milk, Cow's --- Food And Beverage --- And Beverage, Food --- And Beverages, Food --- Beverage, Food And --- Beverages, Food And --- Anion --- Electrolyte --- Dental Cavities --- Dental Cavity --- Cavities, Dental --- Cavity, Dental
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This highly informative and carefully presented book covers the most recent advances as well as comprehensive reviews addressing novel and state-of-the-art topics from active researchers in innovative advanced materials and hybrid materials, concerning not only their synthesis, preparation, and characterization but especially focusing on the applications of such materials with outstanding performance.
non-isothermal crystallisation kinetics --- multi-modal polymer --- graphene-based polymer nanocomposite --- carbon black fillers. --- n/a --- Li4Ti5O12 --- magnesium batteries --- cathodes --- MgCl2 --- garnet --- dual substitution --- spark plasma sintering --- conductivity --- activated carbon --- steam activation --- low-density polyethylene --- electric double layer capacitor --- solid fluoride electrolytes --- ceramics --- LaF3 --- fluorine-ion batteries --- metal current collectors --- electrochemical stability --- cyclic voltammetry --- copper-manganese alloy --- energy storage --- supercapacitor --- graphitic carbon nitride --- TiO2 nanotube --- MoS2 --- Al2O3 --- atomic layer deposition --- Li-ion microbatteries --- nano-catalyst --- noble metals --- TUD-1 --- mesoporous silica --- CO-oxidation --- air purification --- W2C --- WS2 --- hydrothermal --- nanoflowers --- lithium-ion batteries --- CdTe --- nanocrystal --- solar cells --- Spiro --- biomass carbon electrodes --- battery and supercapacitors --- structure–performance relationship --- Lithium-ion batteries --- LiMn2O4 nanoparticles --- Mg-doped --- kinetic and thermodynamic --- thermogravimetric analysis --- Pechini-type sol–gel process --- structure-performance relationship --- Pechini-type sol-gel process
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Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are in vivo molecular imaging methods which are widely used in nuclear medicine for diagnosis and treatment follow-up of many major diseases. These methods use target-specific molecules as probes, which are labeled with radionuclides of short half-lives that are synthesized prior to the imaging studies. These probes are called radiopharmaceuticals. The use of PET and SPECT for brain imaging is of special significance since the brain controls all the body’s functions by processing information from the whole body and the outside world. It is the source of thoughts, intelligence, memory, speech, creativity, emotion, sensory functions, motion control, and other important body functions. Protected by the skull and the blood–brain barrier, the brain is somehow a privileged organ with regard to nutrient supply, immune response, and accessibility for diagnostic and therapeutic measures. Invasive procedures are rather limited for the latter purposes. Therefore, noninvasive imaging with PET and SPECT has gained high importance for a great variety of brain diseases, including neurodegenerative diseases, motor dysfunctions, stroke, epilepsy, psychiatric diseases, and brain tumors. This Special Issue focuses on radiolabeled molecules that are used for these purposes, with special emphasis on neurodegenerative diseases and brain tumors.
SV2A --- SV2B --- SV2C --- microPET --- [18F]UCB-H --- epilepsy --- PBIF --- distribution volume --- blocking assay --- preclinical imaging --- Alzheimer’s disease (AD) --- network measure --- graph theory --- brain network --- positron emission tomography (PET) --- persistent homology --- Phosphodiesterase 2A (PDE2A) --- Positron Emission Tomography (PET) --- Benzoimidazotriazine (BIT) --- fluorinated --- Mouse Liver Microsomes (MLM) --- cyclic nucleotide phosphodiesterase --- PDE2A radioligand --- nitro-precursor --- fluorine-18 --- in vitro autoradiography --- PET imaging --- opioid receptors --- positron emission tomography --- radiotracers --- μOR-, δOR-, κOR- and ORL1-ligands --- movement disorders --- pain --- drug dependence --- GBM --- biomarkers --- Sigma 1 --- Sigma 2 --- PD-L1 --- PARP --- IDH --- Alzheimer’s disease --- Parkinson’s disease --- β-amyloid plaques --- neurofibrillary tangles --- α-synucleinopathy --- diagnostic imaging probes --- orexin receptors --- PET --- radiotracer --- imaging --- alpha 7 --- nicotinic acetylcholine receptors --- nAChR --- autoradiography --- amino acid --- FET --- FACBC --- FDOPA --- immunoPET --- molecular imaging --- glioma --- brain metastases --- adenosine A2A receptor --- rotenone-based mouse model --- [18F]FESCH --- two-step one-pot radiosynthesis
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Radiopharmaceuticals are used in the diagnosis and treatment of various diseases, especially cancer. In general, radiopharmaceuticals are either salts of radionuclides or radionuclides bound to biologically active molecules, drugs, or cells. Tremendous progress has been made in discovering, developing, and commercializing numerous radiopharmaceuticals for the imaging and therapy of cancer. Significant research is ongoing in academia and the pharmaceutical industry to develop more novel radiolabeled compounds as potential radiopharmaceuticals for unmet needs. This Special Issue aims to focus on all aspects of the design, characterization, evaluation, and development of novel radiolabeled compounds for the diagnosis and treatment of cancer and the application of new radiochemistry and methodologies for the development of novel radiolabeled compounds. Outstanding contributions presented in this Special Issue will significantly add to the field of radiopharmaceuticals.
positron emission tomography (PET) --- pyrazoles --- fluorine-18 --- radionuclides --- PET probes --- imaging pharmaceuticals --- hypopharyngeal cancer --- 188Re-liposome --- repeated therapy --- NGS --- microRNA --- aprepitant --- radiopharmaceuticals --- neurokinin 1 receptor antagonist --- radionuclide chelators --- kidney uptake --- cleavable linkers --- neutral endopeptidase (NEP) --- renal brush border enzymes --- prostate-specific membrane antigen (PSMA) --- cancer imaging and therapy --- somatostatin analogs --- radiolabeling --- radionuclide therapy --- imaging --- adrenergic receptor --- positron emission tomography --- radiotracer --- cholecystokinin-2 receptor --- minigastrin --- molecular imaging --- targeted radiotherapy --- lutetium-177 --- EpCAM --- radionuclide --- SPECT --- iodine --- PIB --- breast --- cancer --- PET --- target-specific biomolecules --- immunoPET imaging pharmaceuticals --- production processes --- 124I-labeled monoclonal antibodies --- radiotracers --- AAZTA --- scandium-44 --- FAP --- SA --- DPP --- PREP --- radioiodine labeling --- radioiodination --- biomolecules --- peptides --- proteins --- monoclonal antibodies --- 123,124,125,131I-labeled molecules and biomolecules --- n/a
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Corrosion is a significant issue in many industrial fields. Among other strategies, coatings are by far the most important technology for corrosion protection of metallic surfaces. The Special Issue “Advanced Coatings for Corrosion Protection” has been launched as a means to present recent developments in any type of advanced coating for corrosion protection. This book compiles 15 contributions on metallic, inorganic, polymeric and nanoparticle enhanced coatings that provide corrosion protection as well as other functionalities.
fluorine free --- silanization --- superhydrophobic --- corrosion protection --- self-cleaning --- cathodic protection --- corrosion mitigation method --- potentiodynamic polarization test --- simulation --- pre-insulated pipeline --- zinc-rich coating --- cold galvanized coating --- durability --- magnesium --- microstructure --- coating --- corrosion --- polarization --- apatite --- scanning electrodeposition --- Ni-Fe-Co-P-CeO2 composite coating --- electrochemical corrosion behavior --- corrosion mechanism --- Zn-Al diffusion layer --- mechanical energy aided diffusion --- corrosion resistance --- electrochemistry --- aluminum foam --- electrodeposition --- compression test --- polyurea --- aging mechanism --- morphology --- chemical properties --- phase separation --- hydrogen bond --- magnesium alloy --- MAO coating --- corrosion behavior --- stratification phenomena --- marine environments --- aluminum alloy AlMg6 --- Al2O3 coating --- phase composition --- stress corrosion --- micro-arc oxidation --- polymer --- water hydraulic valve --- cavitation --- erosion --- coating selection --- molecular dynamics --- boride-based cermet --- laser cladding synthesis --- laser power --- hardness --- wear resistance --- MAX phase --- Ti2AlN --- PVD coating --- oxidation --- hydrogen permeation --- tungsten --- W–Cr–C coating --- carburization --- intergranular corrosion --- pitting corrosion --- stainless steel --- passivated --- electrochemical noise --- precipitation hardening --- metallic coatings --- anodizing layers --- passivation --- polymeric coatings --- laser cladding --- PVD --- superhydrophobic coatings --- composite coatings --- n/a --- W-Cr-C coating
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Positron emission tomography (PET) is a very useful technique for medical diagnosis and drug development. Radiopharmaceuticals are a key element in PET techniques and one of the pivotal factors influencing the applications of PET. The aim of this Special Issue of Molecules is to report on the recent research work on a number of aspects of PET radiopharmaceuticals and their preclinical and clinical use. More specifically, the content of this Special Issue includes but is not limited to radiolabeling design, radiosynthesis, synthesis techniques, quality control methodologies, GMP production methods, product formulation, in vitro and in vivo preclinical PET evaluations, clinical evaluations, dosimetry, stability study and metabolite analysis, and modeling.
kinetic analysis --- Siglec-9 --- gallium-68 --- vascular adhesion protein --- VAP-1 --- infection --- inflammation --- osteomyelitis --- animal model --- Staphylococcus aureus --- multiple myeloma --- positron emission tomography/computed tomography --- radiopharmaceuticals --- 18F-fluorodeoxyglucose --- tetrazine ligation --- PET --- SPECT --- indium-11 --- fluorine-18 --- positron emission tomography (PET), defluorination --- isotopic exchange --- silicon-based fluoride acceptor --- bioorthogonal chemistry --- tetrazine --- inverse electron-demand Diels-Alder ligation --- opioid --- naloxone --- overdose --- fentanyl --- carfentanil --- [11C]carfentanil --- positron emission tomography --- receptor occupancy --- pharmacokinetics --- [18F]AlF --- NOTA --- NODAGA --- PODS --- thiol-reactive --- linker --- affibody molecule --- bioconjugation --- EGFR --- tumor imaging --- vulnerable plaque --- molecular imaging --- PET imaging --- nanobody --- single-domain antibody --- sub-millimetre resolution --- AlF-radiolabelling --- preclinical radiopharmaceutical dosimetry --- image-based internal dosimetry --- OLINDA --- MCT1/MCT4 lactate transporter inhibitor --- [18F]FACH --- radiation safety --- sigma-1 receptor availability --- orthotopic xenograft of glioblastoma in mouse --- small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) --- (S)-(−)-[18F]fluspidine --- imaging-based biomarker --- SV2A protein --- PET radiotracers --- synaptic loss --- radiochemistry --- preclinical development --- clinical outcomes --- monocarboxylate transporters (MCTs) --- FACH --- 18F-labeled analog of FACH --- α-CCA --- blood-brain barrier (BBB) --- positron emission tomography (PET) imaging --- peptides --- proteolysis --- metabolic stability
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Polymerized nanoparticles and nanofibers can be prepared using various processes, such as chemical synthesis, the electrochemical method, electrospinning, ultrasonic irradiation, hard and soft templates, seeding polymerization, interfacial polymerization, and plasma polymerization. Among these processes, plasma polymerization and aerosol-through-plasma (A-T-P) processes have versatile advantages, especially due to them being “dry", for the deposition of plasma polymer films and carbon-based materials with functional properties suitable for a wide range of applications, such as electronic and optical devices, protective coatings, and biomedical materials. Furthermore, it is well known that plasma polymers are highly cross-linked, pinhole free, branched, insoluble, and adhere well to most substrates. In order to synthesize the polymer films using the plasma processes, therefore, it is very important to increase the density and electron temperature of plasma during plasma polymerization.
polytetrafluoroethylene --- fluorine depletion --- hydrogen plasma --- VUV radiation --- surface modification --- hydrophilic --- polyamide --- gaseous plasma --- water contact angle --- XPS --- polyamide membranes --- magnetron sputtering --- TiO2 + AgO coatings --- low-pressure plasma --- plasma treatment --- polyaniline (PANI) --- conductive polymer --- plasma polymerization --- aniline --- atmospheric pressure plasma reactor (AP plasma reactor) --- in-situ iodine (I2) doping --- atmospheric pressure plasma --- filler --- polylactic acid --- polymer composite --- polyethylene --- corona discharge --- polyethylene glycol --- adhesion --- polymer --- biomedical applications --- additive manufacturing --- toluidine blue method --- enzymatic degradation --- microwave discharge --- discharges in liquids --- microwave discharge in liquid hydrocarbons --- methods of generation --- plasma properties --- gas products --- solid products --- plasma diagnostics --- plasma modeling --- room temperature growth --- porous polythiophene --- conducting polymer --- NO2 --- gas sensors --- ion beam sputtering --- continuum equation --- plasma --- sublimation --- PA6.6 --- cold plasma --- electrical discharges --- voltage multiplier --- polymers --- oleofobization --- paper --- cellulose --- HMDSO --- atmospheric-pressure plasma --- solution plasma --- polymer films --- nanoparticles --- surface wettability --- graphene oxide --- cyclic olefin copolymer --- GO reduction --- titanium (Ti) alloys --- low-temperature plasma polymerization --- plasma-fluorocarbon-polymer --- anti-adhesive surface --- inflammatory/immunological response --- intramuscularly implantation --- atmospheric pressure plasma jet --- dielectric barrier discharge --- piezoelectric direct discharge --- surface free energy --- test ink --- surface activation --- allyl-substituted cyclic carbonate --- free-radical polymerization --- plasma process --- plasma polymerisation --- plasma deposition --- poly(lactic acid) --- PLA --- ascorbic acid --- fumaric acid --- grafting --- wettability --- BOPP foil --- DCSBD --- VDBD --- ageing --- surface functionalization --- atmospheric pressure plasmas --- glow-like discharge --- single pin electrode --- PANI thin film
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