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The most significant advances in cancer therapy in recent years have involved the development of systemic therapeutics. With improvements in response rates in solid tumors, opportunities have arisen to enhance the effectiveness of surgery. Administration of systemic therapy prior to surgery - neoadjuvant chemotherapy - represents one approach by which clinicians have successfully reduced the extent of surgery and, in some instances, positively impacted on clinical outcomes. This collection of works by expert clinicians from a variety of disciplines represents an exploration of the current knowledge of the role of neoadjuvant chemotherapy in diverse tumor types.
Chemotherapy. --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Pharmacology --- Oncology
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The intent of this book is to provide an overview of current conceptualizations of Pharmacotherapy. The book focuses on three major areas; diagnosis, treatment, and prevention for a wide array of diseases; Cognitive and Psychological disorders (Schizophrenia and Nicotine addiction), Inflammatory disorders (New Chemical anti-inflammatory and Immunotherapy), updated antihypertensive therapy and healing of ulcers with venous origin. A separate chapter is dedicated to the rationality of drug use in earthquake injuries. The last chapter deals with Imaging of potential therapeutic or diagnostic agents in animal models in the early stage of research. We hope this book is useful to a wide range of people, from students first learning about Pharmacotherapy, to advanced clinicians and researchers.
Drug Therapy. --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Pharmacology
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Chemotherapy --- Drug Therapy --- Chimiothérapie --- Chemotherapy. --- Périodiques. --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Pharmacology --- Periodicals.
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"Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze one's own data."--Provided by publisher.
Drug interactions. --- Chemotherapy. --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Pharmacology --- Interactions, Drug --- Side effects --- therapy
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Genetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therapies that are frequently located in genes that regulate DNA methylation and chromatin modifications. Recent studies have shown that distinct subgroups of poor-prognosis tumors lack genetic alterations but are epigenetically regulated, pointing to the critical role of epigenetic modifications in cancer progression. This Special Issue provides novel insights into the mechanisms underlying processes associated with cancer cell plasticity and the development of metastatic disease.
Chemotherapy. --- Tumors. --- Neoplasms --- Tumours --- Pathology --- Cysts (Pathology) --- Oncology --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Pharmacology
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Pharmacotherapy --- Pharmacovigilance --- Pharmacoeconomics --- Pharmaceutical Preparations --- Pharmacy --- Pharmaceutical Services --- Pharmacology --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- pharmacotherapy --- pharmacovigilance --- pharmacoeconomics --- pharmaceutical preparations --- pharmacy --- pharmaceutical services
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Articles that further knowledge and advance the science and application of antimicrobial chemotherapy with antibiotics and antifungal, antiviral and antiprotozoal agents primarily in human medicine.
Chemotherapy --- Drug Therapy. --- Chemotherapy. --- Drug therapy --- Pharmacotherapy --- Therapy, Drug --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Disease --- Pharmaceutical Preparations --- drug therapy --- therapeutic use --- Therapeutics --- Drugs --- Pharmacology --- Pharmacologic Actions
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Drug Therapy --- Pharmacological Phenomena --- Pharmacology --- Drugs --- Pharmacy --- Pharmacologie --- Médicaments --- Pharmacie --- Periodicals --- Périodiques --- Chemotherapy --- Drug Therapy. --- Pharmacological Phenomena. --- Chemotherapy. --- Research --- Research. --- Pharmaceutical research --- Pharmacologic Phenomena --- Pharmacologic Phenomenon --- Pharmacologic Process --- Pharmacological Concepts --- Pharmacological Phenomenon --- Pharmacologic Processes --- Pharmacological Processes --- Concept, Pharmacological --- Concepts, Pharmacological --- Pharmacological Concept --- Phenomena, Pharmacologic --- Phenomena, Pharmacological --- Phenomenon, Pharmacologic --- Phenomenon, Pharmacological --- Process, Pharmacologic --- Processes, Pharmacologic --- Processes, Pharmacological --- Therapy, Drug --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Disease --- Pharmaceutical Preparations --- Drug therapy --- drug therapy --- therapeutic use --- clinical pharmacy --- clinical and experimental pharmacotherapy --- pharmaceuticial health care --- health sciences --- Pharmacologic Actions --- Chemistry --- Medicine --- Materia medica --- Therapeutics --- pharmacotherapy --- pharmaceutical health care --- drug informatics --- pharmacoeconomics --- Pharmacy, Therapeutics, & Pharmacology --- Pharmacotechnology. Preparations --- Pharmacology. Therapy
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Cardiology --- Cardiovascular pharmacology --- Cardiologie --- Pharmacologie cardiovasculaire --- Periodicals. --- Periodicals --- Périodiques --- Cardiology. --- cardiology --- diagnosis and treatment of heart disease --- clinical pharmacology --- pharmacotherapy --- randomized clinical trials --- cardiovascular risk factor --- Heart --- Internal medicine --- Diseases
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The area covered by this book undoubtedly includes a multidisciplinary approach. It combines and uses the wide range of methods and knowledge from a variety of disciplines in chemistry, pharmacology, and biology to synthesize new or extracted natural substances and their characterization, in terms of bioefficiency in different systems, pharmacokinetics, and pharmacodynamics. Importance is placed on revealing the interactions and effects on organisms. The process is long term, ranging from synthesis to potential testing of substances in animal studies, followed by monitoring effects on patients. The purpose is to define molecular targets of the highest efficacy of the prepared drugs, minimizing the undesirable effects. The content of this book is conceived with these intentions.
Chemotherapy. --- Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Pharmacology --- Toxicology and Pharmaceutical Science --- Pharmaceutical Science --- Pharmaceutical Chemistry --- Health Sciences
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