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Book
Neoadjuvant Chemotherapy : Current Applications in Clinical Practice
Authors: ---
ISBN: 9535167863 9533079940 Year: 2012 Publisher: IntechOpen

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Abstract

The most significant advances in cancer therapy in recent years have involved the development of systemic therapeutics. With improvements in response rates in solid tumors, opportunities have arisen to enhance the effectiveness of surgery. Administration of systemic therapy prior to surgery - neoadjuvant chemotherapy - represents one approach by which clinicians have successfully reduced the extent of surgery and, in some instances, positively impacted on clinical outcomes. This collection of works by expert clinicians from a variety of disciplines represents an exploration of the current knowledge of the role of neoadjuvant chemotherapy in diverse tumor types.


Book
Pharmacotherapy
Authors: ---
ISBN: 9535169726 9535105329 Year: 2012 Publisher: IntechOpen

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The intent of this book is to provide an overview of current conceptualizations of Pharmacotherapy. The book focuses on three major areas; diagnosis, treatment, and prevention for a wide array of diseases; Cognitive and Psychological disorders (Schizophrenia and Nicotine addiction), Inflammatory disorders (New Chemical anti-inflammatory and Immunotherapy), updated antihypertensive therapy and healing of ulcers with venous origin. A separate chapter is dedicated to the rationality of drug use in earthquake injuries. The last chapter deals with Imaging of potential therapeutic or diagnostic agents in animal models in the early stage of research. We hope this book is useful to a wide range of people, from students first learning about Pharmacotherapy, to advanced clinicians and researchers.


Periodical
Clinical therapeutics.
ISSN: 1879114X 01492918 Year: 1977 Publisher: [Princeton, N.J.] : New York : Excerpta Medica Elsevier

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Book
Drug-Acceptor Interactions : Modeling Theoretical Tools to Test and Evaluate Experimental Equilibrium Effects.
Author:
ISBN: 9197707104 1351660578 1315159783 1351660586 9197707112 9781315159782 9781351660587 135166056X Year: 2017 Publisher: Co-Action Publishing

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"Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze one's own data."--Provided by publisher.


Book
Genetic and Epigenetic Regulations of Tumor Progression and Metastasis
Authors: --- ---
ISBN: 3036571841 303657185X Year: 2023 Publisher: [Place of publication not identified] : MDPI - Multidisciplinary Digital Publishing Institute,

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Genetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therapies that are frequently located in genes that regulate DNA methylation and chromatin modifications. Recent studies have shown that distinct subgroups of poor-prognosis tumors lack genetic alterations but are epigenetically regulated, pointing to the critical role of epigenetic modifications in cancer progression. This Special Issue provides novel insights into the mechanisms underlying processes associated with cancer cell plasticity and the development of metastatic disease.


Periodical
Revista Portuguesa de Farmacoterapia.
Author:
ISSN: 21837341 1647354X Year: 2009 Publisher: [Estoril, Portugal] : Formifarma, Lda.


Periodical
Revista española de quimioterapia.
Author:
ISSN: 19889518 Year: 1988 Publisher: [Barcelona] : Prous Science

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Abstract

Articles that further knowledge and advance the science and application of antimicrobial chemotherapy with antibiotics and antifungal, antiviral and antiprotozoal agents primarily in human medicine.


Periodical
Journal of Pharmaceutical Health Care and Sciences.
Author:
ISSN: 20550294 Year: 2015 Publisher: London : BioMed Central,

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Periodical
Rat͡sionalʹnai͡a farmakoterapii͡a v kardiologii
ISSN: 18196446 22253653 Year: 2005 Publisher: [Moscow] : "Stolichnai͡a Izdatelʹskai͡a Kompanaii͡a


Book
Medicinal Chemistry
Authors: --- ---
ISBN: 1789851742 1789851734 1839620773 Year: 2019 Publisher: IntechOpen

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Abstract

The area covered by this book undoubtedly includes a multidisciplinary approach. It combines and uses the wide range of methods and knowledge from a variety of disciplines in chemistry, pharmacology, and biology to synthesize new or extracted natural substances and their characterization, in terms of bioefficiency in different systems, pharmacokinetics, and pharmacodynamics. Importance is placed on revealing the interactions and effects on organisms. The process is long term, ranging from synthesis to potential testing of substances in animal studies, followed by monitoring effects on patients. The purpose is to define molecular targets of the highest efficacy of the prepared drugs, minimizing the undesirable effects. The content of this book is conceived with these intentions.

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