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Hematology has constantly been advancing in parallel with technological developments that have expanded our understanding of the phenotypic, genetic, and molecular complexity and extreme clinical and biological heterogeneity of blood diseases. This has in turn allowed for developing more effective and less toxic alternative therapeutic approaches directed against critical molecular pathways. The continuous and rather extensive influx of new information regarding the key features and underlying mechanisms as well as treatment options in hematology requires a frequent update of this topic. The primary objective of this book is to provide the specialists involved in the clinical management and experimental research in hematological diseases with comprehensive and concise information on some important theoretical and practical developments in the biology, clinical assessment, and treatment of patients, as well as on some molecular and pathogenetic mechanisms and the respective translation into novel therapies.

Hematology. --- Haematology --- Internal medicine --- Blood --- Diseases --- Medicine --- Hematological Oncology --- Hematology --- Health Sciences

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This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries.

Multiple myeloma. --- Kahler's disease --- Plasma cell myeloma --- B cells --- Monoclonal gammopathies --- Plasmacytoma --- Tumors --- Medicine --- Hematological Oncology --- Hematology --- Health Sciences

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Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means ""sea"", and emia means ""blood""), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.

Thalassemia. --- Hemolytic anemia. --- Anemia --- Hemolysis and hemolysins --- Cooley's anemia --- Erythroblastic anemia --- Mediterranean anemia --- Mediterranean disease --- Thalassanemia --- Hemoglobinopathy --- Hemolytic anemia --- Medicine --- Hematological Oncology --- Hematology --- Health Sciences

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Hematological oncology --- Hematologic Diseases. --- Neoplasms. --- Hematological oncology. --- Hematology --- Oncology --- Benign Neoplasms --- Malignancy --- Malignant Neoplasms --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Malignant Neoplasm --- Neoplasias --- Neoplasm, Benign --- Neoplasm, Malignant --- Neoplasms, Malignant --- Tumor --- Medical Oncology --- Hematological Diseases --- Blood Diseases --- Blood Disease --- Disease, Blood --- Disease, Hematologic --- Disease, Hematological --- Diseases, Blood --- Diseases, Hematologic --- Diseases, Hematological --- Hematologic Disease --- Hematological Disease --- Neoplasms --- Hematologic Diseases --- Hematologic Neoplasms. --- Hematologic Malignancy --- Hematological Malignancies --- Hematological Neoplasms --- Hematopoietic Malignancies --- Malignancies, Hematologic --- Malignancy, Hematologic --- Neoplasms, Hematologic --- Neoplasms, Hematopoietic --- Hematologic Malignancies --- Hematopoietic Neoplasms --- Hematologic Neoplasm --- Hematological Malignancy --- Hematological Neoplasm --- Hematopoietic Malignancy --- Hematopoietic Neoplasm --- Malignancies, Hematological --- Malignancies, Hematopoietic --- Malignancy, Hematological --- Malignancy, Hematopoietic --- Neoplasm, Hematologic --- Neoplasm, Hematological --- Neoplasm, Hematopoietic --- Neoplasms, Hematological --- Oncology. Neoplasms --- Pathological haematology

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Hematology --- Oncology --- Hematological oncology --- Hématologie --- Cancérologie --- Hématocancérologie --- Periodicals --- Périodiques --- Blood --- Hematology. --- Oncology. --- Diseases --- Diseases. --- Haematology --- Clinical hematology --- Hematologic diseases --- haematology --- oncology --- Tumors --- Internal medicine --- Body fluids --- Fear of blood --- Oncology. Neoplasms --- Pathological haematology --- Pathology --- Neoplasms. --- Benign Neoplasms --- Malignancy --- Malignant Neoplasms --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Benign Neoplasm --- Cancers --- Malignancies --- Malignant Neoplasm --- Neoplasias --- Neoplasm, Benign --- Neoplasm, Malignant --- Neoplasms, Malignant --- Tumor --- Medical Oncology --- Neoplasms --- Hematologic Diseases. --- Hematological Diseases --- Blood Diseases --- Blood Disease --- Disease, Blood --- Disease, Hematologic --- Disease, Hematological --- Diseases, Blood --- Diseases, Hematologic --- Diseases, Hematological --- Hematologic Disease --- Hematological Disease --- Hematologic Neoplasms. --- Hematologic Malignancy --- Hematological Malignancies --- Hematological Neoplasms --- Hematopoietic Malignancies --- Malignancies, Hematologic --- Malignancy, Hematologic --- Neoplasms, Hematologic --- Neoplasms, Hematopoietic --- Blood Cancer --- Hematologic Malignancies --- Hematopoietic Neoplasms --- Blood Cancers --- Cancer, Blood --- Hematologic Neoplasm --- Hematological Malignancy --- Hematological Neoplasm --- Hematopoietic Malignancy --- Hematopoietic Neoplasm --- Malignancy, Hematological --- Malignancy, Hematopoietic --- Neoplasm, Hematologic --- Neoplasm, Hematological --- Neoplasm, Hematopoietic --- Medical Oncology. --- Clinical Oncology --- Oncology, Medical --- Oncology, Clinical --- Oncologia --- Hematologia