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Humans, animals and microorganisms all share the same planet, the last playing critical roles in the cycling of nitrogen and sulfur in nature and the degradation of organic materials. Unfortunately, micro-organismal populations also include infectious bacteria and viruses that cause diseases, with a few that have fatal consequences. We chose veterinary bacterial zoonoses as our Research Topic with the aim of delivering up-to-date scientific knowledge on the subject, addressing the topics of detection approaches, vaccine development and host immune response. Our Research Topic alludes to the One Health approach in addressing three important bacterial diseases, Brucella, Mycobacteria and Chlamydia. A short chapter also elaborates on a highly pathogenic field isolate of Mycobacterium avium spp. Avium and an atypical enteropathogenic Escherichia coli O98 as evolving zoonotic risks. The cover illustration is intended to raise our awareness of the fact that pets play a role in our life as passionate and compassionate friends, but that they also pose a health risk due to carrying a bacterial or a viral zoonotic agent. We hope our Research Topic will further the pursuit of these topics and spark research in other important diseases.
microRNAs --- One health --- Chlamydia --- Mycobacteria --- Brucella --- Vaccine --- Detection --- Epidemiology --- MLVA --- ELISA
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History of Belgium and Luxembourg --- Belpaire, Marie-Elisabeth --- anno 1910-1919 --- Flemish movement. --- Mouvement flamand --- Belpaire, Marie-Elisabeth, --- #GGSB: Geschiedenis (Belgie) --- Flemish movement --- 929 BELPAIRE, MARIA ELISA --- #C9112 --- Belpaire, Maria Elisa --- Belpaire, Maria Elisa, --- Belpaire, M. E. --- Belpaire, Maria Elisabeth --- Geschiedenis (Belgie) --- 960 --- levensbeschrijvingen --- biographies et mémoires
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"Black Cosmopolitans examines the lives and thought of three extraordinary black men—Jacobus Capitein, Jean-Baptiste Belley, and John Marrant—who traveled extensively throughout the eighteenth-century Atlantic world. Unlike millions of uprooted Africans and their descendants at the time, these men did not live lives of toil and sweat in the plantations of the New World. Marrant was born free, while Capitein and Belley became free when young, and this freedom gave them not only mobility but also the chance to make significant contributions to print culture. As public intellectuals, Capitein, Belley, and Marrant developed a cosmopolitan vision of the world anchored in the republican ideals of civic virtue and communal life, and so helped radicalize the calls for freedom that were emerging from the Enlightenment.Relying on sources in English, French, and Dutch, Christine Levecq shows that Calvinism, the French Revolution, and freemasonry were major inspirations for this republicanism. By exploring these cosmopolitan men’s connections to their black communities, she argues that the eighteenth-century Atlantic world fostered an elite of black thinkers who took advantage of surrounding ideologies to spread a message of universal inclusion and egalitarianism."
Literature & literary studies --- calvinism --- French revolution --- Atlantic history --- slave trade --- republicanism --- Belley, Jean-Baptiste, --- Capitein, J. E. J. --- Marrant, John, --- Marrant, --- Capitein, Jacobus Elisa Joannes, --- Literature. --- Cosmopolitanism.
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The history of science can teach modern men that our understanding of life is to a great extent based on the accuracy of the analytical methods that we use and, on our readiness to oppose dogmatic opinions, which are based on outdated methods and black/white approaches to the major questions raised by mankind in the past. The recent decades have brought a lot of new insights into the fundamentals of the active principles of reactive oxygen species that are necessary for living cells, but which also cause dangerous pathophysiological processes. Accordingly, although they were previously considered to be the most undesired toxic compounds generated as the final products of the oxidative degradation of lipids, reactive aldehydes are now considered to play important roles both in health and in major diseases. Represented mostly by 4-hydroxynonenal (HNE), a substance discovered only fifty years ago, reactive aldehydes are the focus of research not only because of their toxicity but also because of their positive effects regulating the most important metabolic processes such as growth of living cells or the death of cells. Better understanding the interactions between reactive aldehydes and natural or synthetic antioxidant substances might eventually help us to better monitor, prevent and control modern diseases, thus building pillars for the development of the modern, multidisciplinary life sciences and integrative medicine of the 21st century.
free radicals --- lipids --- cell-based ELISA --- reactive aldehydes --- antioxidants --- fertility --- reactive oxygen species ROS --- human diseases --- lipid peroxidation --- 4-hydroxynonenal --- 1 --- 4-Dihydropyridine Derivatives --- omics --- pathophysiology --- growth control --- cannabinoids --- plant extract --- mass spectrometry --- cell cultures --- cancer --- aging --- oxidative stress --- immunochemistry
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With recent technological advances in multiple research fields such as materials science, micro-/nano-technology, cellular and molecular biology, bioengineering and the environment, much attention is shifting toward the development of new detection tools that not only address needs for high sensitivity and specificity but fulfil economic, environmental, and rapid point-of-care needs for groups and individuals with constrained resources and, possibly, limited training. Miniaturized fluidics-based platforms that precisely manipulate tiny body fluid volumes can be used for medical, healthcare or even environmental (e.g., heavy metal detection) diagnosis in a rapid and accurate manner. These new detection technologies are potentially applicable to different healthcare or environmental issues, since they are disposable, inexpensive, portable, and easy to use for the detection of human diseases or environmental issues—especially when they are manufactured based on low-cost materials, such as paper. The topics in this book (original and review articles) would cover point-of-care detection devices, microfluidic or paper-based detection devices, new materials for making detection devices, and others.
sepsis --- PCT --- procalcitonin --- immunoassay --- antibiotic --- chemiluminescence --- immunofluorescence --- n/a --- origami-based paper analytic device --- origami ELISA --- IgG --- paraquat --- diabetes mellitus --- ketone bodies --- human breath --- acetone --- beta-hydroxybutyrate --- acetoacetate --- gas chromatography-mass spectrometry (GC-MS) --- type 2 diabetes --- diabetic peripheral neuropathy (DPN) --- electrocardiogram (ECG) --- photoplethysmography (PPG) --- percussion entropy index (PEI) --- decision making, computer-assisted --- decision support systems, clinical --- precision medicine --- computational biology --- molecular tumor board --- cBioPortal --- requirements analysis --- neoplasms --- pH value --- diagnosis --- skin --- wound --- blood --- coagulation --- hemostasis --- point of care --- ROTEM --- TEG --- thromboelastography --- VHA --- viscoelastic testing --- partial-thickness burn injury --- burn blister fluid --- P-ELISA --- angiogenin --- burn wound healing --- Alzheimer’s disease --- β-amyloid peptide --- paper-based ELISA --- P-ELISA, point of care testing --- microfluidics --- point-of-care diagnostics --- antimicrobial resistance --- lab-on-a-chip --- capillary-driven flow --- capillary action --- detections --- smartphone imaging --- lateral flow assay --- immuno-chromatographic --- gold nanoparticles sensor --- UV/Vis spectrophotometer --- malaria pan rapid diagnostic strip --- point-of-care --- Alzheimer's disease
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Crop contamination by mycotoxins is a global problem that poses significant economic burdens due to a number of factors, including the food/feed losses that are caused by reduced production rates; the resulting adverse effects on human and animal health and productivity; and the trade losses associated with the costs incurred by inspection, sampling, and analysis before and after shipments. In this scenario, the development of fit-for-purpose analytical methods for regulated and (re)-emerging mycotoxins continues to be a dynamic research area. Some of the current trends in this research area are presented in this book. The collected contributions address either the need for improved methods for mycotoxin detection addressed by new or incoming regulation (ergot alkaloids and Alternaria toxins) as well as methods for the detection of multiple mycotoxins. New approaches to enhance the performance of well-established methodologies, such as the enzyme-linked immunosorbent assay (ELISA) and fluorescence polarization immunoassays (FPIA), are also addressed.
FPIA --- mycotoxin --- OTA --- detection methods --- food safety --- monoclonal antibody (mAb) --- tracer --- HPLC --- trichothecenes --- zearalenone --- Fusarium toxins --- wheat --- liquid chromatography–mass spectrometry --- official control --- collaborative study --- ergot alkaloids --- sum parameter method --- hydrazinolysis --- esterification --- swine feed --- dairy feed --- UHPLC-MS/MS --- aflatoxin B1 --- recombinant AflR gene --- VICAM --- I-ELISA --- peanut --- wheat flour --- milk powder --- LC-MS/MS method --- cereal products --- occurrence --- alternariol --- antibody --- ELISA --- hapten design --- immunoassay --- linker site --- n/a --- liquid chromatography-mass spectrometry
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Throughout history, wildlife has been an important source of infectious diseases transmissible to humans. Today, zoonoses with a wildlife reservoir constitute a major public health problem, affecting all continents. The importance of such zoonoses is increasingly recognized, and the need for more attention in this area is being addressed. The total number of zoonoses is unknown, some 1,415 known human pathogens have been catalogued, and 62% are of zoonotic origin [1]. With time, more and more human pathogens are found to be of animal origin. Moreover, most emerging infectious diseases in humans are zoonoses. Wild animals seem to be involved in the epidemiology of most zoonoses and serve as major reservoirs for transmission of zoonotic agents to domestic animals and humans [2]. The concept of the ‘One Health’ approach involving collaboration between veterinary and medical scientists, policy makers, and public health officials, is necessary to foster joint cooperation and control of emerging zoonotic diseases [3]. Zoonotic diseases caused by a wide range of arthropods, bacteria, helminths, protozoans, and viruses can cause serious and even life-threatening clinical conditions in animals, with a number of them also affecting the human population due to their zoonotic potential. The aim of the current Special Issue is to cover recent and novel research trends in zoonotic diseases in wildlife, including the relevant topics related to wildlife, zoonosis, public health, emerging diseases, infectious diseases and parasitic diseases.
west nile virus --- arbovirus --- zoonotic --- macaque --- bats --- c-ELISA --- RT-PCR --- Anaplasma phagocytophilum --- zoonosis --- tick --- wild ungulates --- phylogenesis --- molecular epidemiology --- Coxiella burnetii --- Q fever --- serology --- epidemiology --- wildlife --- European bison --- micromammals --- Cryptosporidium --- Giardia --- Blastocystis --- Enterocytozoon bieneusi --- Balantioides coli --- Troglodytella --- non-human primates --- rats --- zoological garden --- one health --- Helicobacter spp. --- PCR --- Sus scrofa --- Meles meles --- badger --- tuberculosis --- Mycobacterium tuberculosis complex --- P22 ELISA --- isolation --- cattle --- Atlantic Spain --- filter card --- faeces --- transportation --- storage --- preservation --- Giardia duodenalis --- Cryptosporidium hominis --- seroprevalence --- ruminants --- humans --- dust --- aerosols --- Salmonella --- turtles --- wildlife rescue centres --- camera-traps --- interactions --- wildlife-livestock interface --- non-tuberculous mycobacteria --- Leptospira interrogans --- microscopic agglutination test --- Slovenia --- n/a
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Monoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases.
PRAME --- mAb --- bio-layer interferometry --- epitope identification --- monoclonal antibody --- free radical --- protein aggregation --- oxidation --- excipient --- foot-and-mouth disease virus --- type O --- type A --- phage display --- antibody --- competitive ELISA --- atherosclerosis --- nano-emulsion --- magnetic resonance imaging --- stealth --- human antibody --- C. auris --- candidiasis --- multidrug resistance --- monoclonal antibodies --- universal antibodies --- cell wall --- passive immunization --- cell-based panning --- semi-automated cell panning --- FGFR3-specific antibody
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This book presents the most important issues related to infections with Mycoplasma bovis, an etiological agent of many disorders in cattle, such as bronchopneumonia, mastitis, arthritis, otitis, keratoconjunctivitis, meningitis, and endocarditis. It consists of one review and eight research articles that discuss lung local immunity in experimental M. bovis pneumonia, antimicrobial susceptibility of M. bovis isolates, aspects related to M. bovis antibody testing, new data on the efficacy of seminal extender in M. bovis, as well as the importance of imported bull examination for this pathogen.
Mycoplasma bovis --- cattle --- leukocytes --- phagocytosis --- oxygen metabolism --- bovine respiratory disease --- prevalence --- minimum inhibitory concentration --- antimicrobial resistance --- mutations --- Spain --- whole genome sequencing --- MIC --- cgMLST --- Bovine Respiratory Disease --- genetic diversity --- antimicrobial --- susceptibility --- resistance --- genotype --- rRNA --- macrolides --- feedlot --- beef --- diagnosis --- control --- immune response --- ELISA --- disease --- bovine semen --- antibiotics --- prevention --- DNA extraction --- n/a
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Deze publicatie verschijnt naar aanleiding van het honderdjarig bestaan van de 'Belpaire-school'. De oprichting en uitbouw van deze school was één van de levenswerken van Marie Elisabeth Belpaire ( 1853-1948). Bij het begin van de twintigste eeuw werd aan het meisjesonderwijs in Vlaanderen weinig aandacht besteed. Goed middelbaar onderwijs voor meisjes was schaars, en dus ontbrak ook een degelijke voorbereiding tot het hoger onderwijs. Marie Elisabeth Belpaire heeft zeker haar sporen op dat vlak verdiend. Zij heeft verscheidene meisjesscholen opgericht zoals de Anna Bijnsschool, het Belpaire instituut, de extension universitaire, de Cours supérieur en de Sint-Lutgardisschool. Zij heeft ook een cruciale rol gespeeld in de oprichting van de Katholike Vlaamse Hogeschool voor vrouwen in 1919.
Belpaire, Marie-Elisabeth --- Belpaire, Marie-Elisabeth, --- Belpaire, Maria-Elizabeth, --- Belpaire, Marie-Elisabeth (1853-1948) --- hoger onderwijs buiten de universiteit (x) --- #KVHB:Belpaire, Marie Elisabeth --- #KVHA:Geschiedenis; Antwerpen --- #KVHA:Belpaire, Marie Elisabeth --- 37.009 --- Geschiedenis van opvoeding en pedagogiek --- Geschiedenis van België en Luxemburg --- History of education and educational sciences --- History of Belgium and Luxembourg --- Belgium --- Vlaanderen. --- Authors, Belgian --- Flemish movement --- Women --- Ecrivains belges --- Mouvement flamand --- Femmes --- Biography --- Education --- History --- Biographie --- Biographies --- Histoire --- Antwerp (Belgium) --- Anvers (Belgique) --- Belgique --- vrouwenemancipatie --- Antwerpen --- vrouwen --- KADOC - Documentatie- en Onderzoekscentrum voor Religie, Cultuur en Samenleving (1977-) --- C6 --- onderwijs --- #A0206A --- 950 Vlaamse Beweging --- 949.3 --- Opvoeding, onderwijs, wetenschap --- Biography. --- 949.3.09 --- 949.3.09 Geschiedenis van de Vlaamse beweging --- Geschiedenis van de Vlaamse beweging --- Belpaire, Maria Elisabeth --- Belpaire, Maria Elisa --- Belpaire, M. E. --- Belpaire, Maria Elisa, --- Single-sex education --- Literature --- Vocational education --- Biographical details --- Book
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