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Periodical
Cadernos do IME. Série Matemática
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ISSN: 14139030 22362797

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Periodical
Mathematical & Computational Applications
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ISSN: 1300686X 22978747 Year: 1995 Publisher: [S.l.] Association for Scientific Research


Periodical
Journal of Applied Mathematics and Computational Mechanics
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ISSN: 22999965 23530588


Book
Modeling excitable tissue : the EMI framework
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ISBN: 3030611574 3030611566 Year: 2021 Publisher: Springer Nature

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This open access volume presents a novel computational framework for understanding how collections of excitable cells work. The key approach in the text is to model excitable tissue by representing the individual cells constituting the tissue. This is in stark contrast to the common approach where homogenization is used to develop models where the cells are not explicitly present. The approach allows for very detailed analysis of small collections of excitable cells, but computational challenges limit the applicability in the presence of large collections of cells.


Book
Inevitable aging? : contributions to evolutionary-demographic theory
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ISBN: 1281179647 9786611179649 3540766561 3540766553 3642095348 Year: 2008 Publisher: Berlin : Springer,

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Honored by the Max Planck Society with the Otto Hahn Medal 2007 for outstanding scientific achievements Aging is inevitable: this is gerontological dogma. And humans do inevitably grow old, which is probably why it seems so unlikely to us that other forms of life could escape aging. Escaping aging is not escaping death. Death is an inherent part of life, and it can strike any time. But the question is whether death necessarily becomes more likely as life proceeds. And it does not. The theoretical results in this monograph indicate that life provides alternative strategies. While some organisms will deteriorate over adult ages, for others mortality appears to fall or remain constant, at least over an extended period of life after reproductive maturity. This is empirically observed especially for species that keep on growing during adult ages. Perhaps the diversity of aging matches the diversity of life. My thesis, the central insight of this monograph, is: to deeply understand why some species age it is necessary to understand why other species do not.

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