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Book
Ongoing Research in Jawed Fish Immunity: Structural and Functional Studies at the Protein and Cellular Levels
Authors: ---
Year: 2020 Publisher: Frontiers Media SA

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Abstract

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


Book
Dendritic Cells
Authors: ---
ISBN: 1789844177 1789844169 1838817875 Year: 2018 Publisher: IntechOpen

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Since their discovery in 1973 by Zanvil Cohn and Ralph Steinman (Nobel Prize in Physiology and Medicine, 2011), dendritic cells (DCs) continue to intrigue research scientists as their new markers, subpopulations and properties are being detected and the relevant literature is being doubled each year. This book combines the most comprehensive reviews of several critical aspects of DC biology and function written by a group of international experts in the field. The first section briefly discusses recent advances in DC subtypes, phenotypes, and functions in different diseases. The following sections look closely at DC phenotyping, DC-NK cell interplay, and roles of DC in bone loss and repair and parasitic infections. The final section on DC and cancer includes perspectives on DC vaccination based on modifications and therapeutic applications.


Book
Cross Talk between Lymph Node Lymphatic Endothelial Cells and T Cells in Inflammation and Cancer
Authors: ---
Year: 2017 Publisher: Frontiers Media SA

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Lymphocytes constantly survey the lymph nodes in search for potential infection by a pathogen. They enter the afferent lymphatic vessel that serves as a conduit to transport the motile lymphocytes to the draining lymph node. Lymphatic vessels (LVs) are present in most vascularized tissues. They are traditionally regarded as passive conduits for soluble antigens and leukocytes. Afferent LVs begin as blind ended capillaries, which give rise to collecting vessels that merge and connect with draining lymph nodes (dLNs). Initial lymphatic capillaries are composed of Lymphatic Endothelial Cells (LECs) connected by discontinuous cell junctions, which join to form larger collecting lymphatic vessels, and ultimately feed into the LN subcapsular sinus. Within the LN, LECs are localized to the subcapsular, cortical, and medullary sinuses, where they interact with incoming and exiting leukocytes. LECs, and in general LN stromal cells, have emerged in the recent years as active players in the immune response. In support to this,studies have shown that the immune response generated during inflammation and under pathologic conditions is accompanied by modeling of the LVs and generation of new lymphatics, a process known as lymphangiogenesis. These facts strongly suggest that LECs and stromal LN cells in general, are not inert players but rather are part of the immune response by organizing immune cells movement, exchanging information and supplying survival factors. The purpose of this research topic is to review the role of the LECs during immune homeostasis and cancer. Considering the critical role of lymphangiogenesis in many pathologies like chronic and acute inflammation, autoimmunity, wound healing, graft rejection, and tumor metastasis, it is important to understand the molecular mechanisms that govern the cross talks between the LECs and immune cells during homeostasis and inflammation.


Book
Cancer Immunology
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The past decade has seen immunotherapy rise to the forefront of cancer treatment. This Special Issue of Cancers aims to elaborate on the latest developments, cutting-edge technologies, and prospects in cancer immunology and immunotherapy. Seventeen exceptional studies, including original contributions and review articles, written by international scientists and physicians, primarily concerning the fields of tumor biology, cancer immunology, therapeutics, and drug development, comprise the main body of this Special Issue.

Keywords

NKG2D --- CAR T --- IL-7 --- prostate cancer --- cell therapy --- CD19-CAR-T --- B cell aplasia --- KIR --- PD-1 --- inhibitory CAR --- tumor-infiltrating lymphocytes --- tumor microenvironment --- immunotherapy --- NK cells --- cancer stem cells (CSCs) --- antibody-dependent cellular cytotoxicity (ADCC) --- differentiation --- cytotoxicity --- IFN-γ --- osteoclasts --- MICA/B mAb --- DNA methylation --- RNA methylation --- S-adenosylmethionine (SAM) --- cancer --- innate immunity --- adaptive immunity --- T cells --- m6A --- PD-L1 --- resistance --- immune checkpoints --- cancer vaccine --- combination immunotherapy --- TCR diversity --- organ transplantation --- carcinoma --- epidemiologic studies --- immunosuppression --- CTLA-4 --- Treg cells --- immune checkpoint inhibitors --- CD28 --- antigen-presenting cells --- IL15 --- colon cancer --- melanoma --- uveal --- BAP1 --- anti-PD-1 --- anti-CTLA-4 --- TIL --- classical and endemic Kaposi Sarcoma --- systemic treatment --- multi-state modelling --- treatment free interval --- chemotherapy --- interferon --- triple negative breast cancer --- immunomodulation --- bispecific antibody --- sortase A --- chemo-enzymatic approach --- anti-CD20 antibody --- Fab --- BiFab --- colorectal cancer --- dendritic cells --- Atypical Chemokine Receptor 4 (ACKR4) --- T-cell priming --- immune checkpoint blockade --- primary liver cancer --- kynurenine pathway --- immune evasion --- indoleamine 2,3 dioxygenase 1 --- tryptophan 2,3 dioxygenase 2 --- IDO inhibitor --- antigen presenting cells --- n/a


Periodical
Cell metabolism.
ISSN: 19327420 15504131 Year: 2005 Publisher: [Cambridge, MA] : Cell Press,

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Keywords

Cell metabolism --- Cells --- Metabolic Diseases --- Homeostasis --- metabolism --- Metabolic Diseases. --- Homeostasis. --- Cellules --- Cell metabolism. --- Métabolisme cellulaire. --- metabolism. --- Métabolisme --- Autoregulation --- Diseases, Metabolic --- Thesaurismosis --- Disease, Metabolic --- Metabolic Disease --- Thesaurismoses --- Metabolism --- Cell --- Cell Biology --- Cellular control mechanisms --- Métabolisme cellulaire. --- Métabolisme --- Cytology --- cells. --- metabolic diseases. --- homeostasis. --- biochemistry --- physiology --- anabolism --- biocatalysis --- biosynthesis --- carbohydrate metabolism --- carbon metabolism --- catabolism --- catabolite repression --- copper metabolism --- dealkylation --- energy metabolism --- hormone metabolism --- lipid metabolism --- metabolic detoxification --- metabolic sequestration --- mineral metabolism --- nitrogen metabolism --- pharmacokinetics --- protein metabolism --- steroid metabolism --- vitamin metabolism --- water metabolism --- metabolic flux analysis --- metabolic studies --- metabolites --- metabolome --- metabolomics --- oxidative stress --- cell biology --- acinar cells --- adipocytes --- aleurone cells --- antigen-presenting cells --- bacteriocytes --- blood cells --- bone marrow cells --- bundle sheath cells --- chondrocytes --- chromaffin cells --- chromatophores --- coelomocytes --- cultured cells --- endothelial cells --- epithelial cells --- eukaryotic cells --- fibroblasts --- germ cells --- giant cells --- gonadotropic cells --- granulosa cells --- guard cells --- hemocytes --- hepatocytes --- islets of Langerhans --- keratinocytes --- kidney cells --- Leydig cells --- luteal cells --- mast cells --- myocytes --- neoplasm cells --- neurosecretory cells --- nurse cells --- osteoblasts --- osteoclasts --- phagocytes --- plant root cells --- prokaryotic cells --- Schwann cells --- Sertoli cells --- somatic cells --- splenocytes --- spores --- stem cells --- stromal cells --- tenocytes --- teratocytes --- thecal cells --- vegetative cells --- artificial cells --- cell transplantation --- cell viability --- cellular microenvironment --- physiological regulation --- autoregulation --- glucagon-like peptide 2 --- glucoregulation --- glucose tolerance tests --- metabolic disorders --- noninfectious diseases --- acidosis --- alkalosis --- calcinosis --- carbohydrate metabolism disorders --- dehydration (animal physiology) --- developmental orthopedic disease --- diabetes --- hypercalcemia --- hyperinsulinemia --- hyperkalemia --- hyperketonemia --- hypocalcemia --- hypokalemia --- hypomagnesemia --- hyponatremia --- inherited metabolic diseases --- iron overload --- ketonemia --- ketonuria --- lipid metabolism disorders --- osteomalacia --- refeeding syndrome --- uremia --- malnutrition --- Metabolisme cel·lular --- Citologia --- Homeòstasi


Periodical
Molecular vision.
ISSN: 10900535 Year: 1995 Publisher: Atlanta, GA : [publisher not identified],

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Keywords

Vision --- Eye --- Oeil --- Genetic aspects --- Periodicals --- Cytology --- Molecular aspects --- Aspect génétique --- Périodiques --- Cytologie --- Aspect moléculaire --- Cells. --- Molecular Biology. --- Vision. --- Œil --- genetics. --- Eyesight --- Seeing --- Sight --- Light Signal Transduction, Visual --- Ocular Vision --- Visual Light Signal Transduction --- Visual Phototransduction --- Visual Transduction --- Phototransduction, Visual --- Transduction, Visual --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Cell --- Eyeball --- Eyes --- Visual system --- Senses and sensation --- Blindfolds --- Physiological optics --- Ophthalmology --- Visual Perception --- Genetic Phenomena --- Cell Biology --- Face --- Photoreceptors --- Vision, Ocular. --- Vision, Ocular --- Aspect moléculaire --- Aspect génétique --- Cytology. --- molecular biology --- ophthalmology --- genetics --- biochemistry --- cell biology --- Cells --- Molecular Biology --- cells. --- molecular biology. --- vision. --- genetics --- Biological Sciences --- animal genetics --- cytogenetics --- gender --- genetic equilibrium --- genetic factors --- genetic relationships --- genetic selection --- genetic stability --- genetic structure --- genetic traits --- genetic vectors --- genomics --- human genetics --- immunogenetics --- inheritance (genetics) --- landscape genetics --- maternal effect --- metabolomics --- microbial genetics --- molecular genetics --- nutrigenomics --- paternal effect --- phenomics --- phenotype --- plant genetics --- population genetics --- proteomics --- quantitative genetics --- reproductive fitness --- sex determination --- transcriptomics --- biotechnology --- breeding --- genetic models --- genetic resources --- geneticists --- eyesight --- visual phototransduction --- visual transduction --- ocular physiology --- sensation --- color vision --- night vision --- eye diseases --- ophthalmology --- photoreceptors --- sensory properties --- vision disorders --- visual cortex --- visual perception --- bioinformatics --- molecular dynamics --- molecular epidemiology --- molecular models --- molecular systematics --- cell biology --- acinar cells --- adipocytes --- aleurone cells --- antigen-presenting cells --- bacteriocytes --- blood cells --- bone marrow cells --- bundle sheath cells --- chondrocytes --- chromaffin cells --- chromatophores --- coelomocytes --- cultured cells --- endothelial cells --- epithelial cells --- eukaryotic cells --- fibroblasts --- germ cells --- giant cells --- gonadotropic cells --- granulosa cells --- guard cells --- hemocytes --- hepatocytes --- islets of Langerhans --- keratinocytes --- kidney cells --- Leydig cells --- luteal cells --- mast cells --- myocytes --- neoplasm cells --- neurosecretory cells --- nurse cells --- osteoblasts --- osteoclasts --- phagocytes --- plant root cells --- prokaryotic cells --- Schwann cells --- Sertoli cells --- somatic cells --- splenocytes --- spores --- stem cells --- stromal cells --- tenocytes --- teratocytes --- thecal cells --- vegetative cells --- artificial cells --- cell transplantation --- cell viability --- cellular microenvironment --- Cellules. --- sight (sense) --- Organisms --- Biologia molecular. --- Visió.

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