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Clinicians, scientists, and health care professionals use biomarkers or biological markers as a measure of a person’s present health condition or response to interventions. An ideal -biomarker should have the following criteria: (I) ability to detect fundamental features of the disease, (II) ability to differentiate from other closely related diseases, (III) ability to detect early stages and stages of progression, (IV) the method should be highly reliable, easy to perform and inexpensive, and (V) sample sources should be easily accessible from body. Most of the chapters in this book follow the basic principle of biomarkers.

Biological Markers. --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Biochemistry --- Indicators (Biology) --- Medicine --- Diagnostics --- Clinical Pathology --- Health Sciences

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This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of disease prognosis. Chapters in Part I focus on biomarkers for cancer, including breast cancer and pancreatic cancer, as well as circulating microRNA profiling in cancer biomarker discovery. Chapters in Part II focus on biomarkers of other diagnoses/diseases, including sepsis, childhood renal diseases, pulmonary diseases, Alzheimer's, leishmaniasis, and heart failure. This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of diseases prognosis. The book is of considerable importance for a broad range of people including researchers, clinicians, and university students.

Biochemical markers. --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Biochemistry --- Indicators (Biology) --- Medicine --- Engineering Technology in Medicine --- Medical Instrument Technology --- Health Sciences

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This book presents exclusive and comprehensive insight into the detailed molecular mechanisms of osteoarthritis (OA) initiation, progression and current advancements in the field. Inputs from clinician scientists, research and expertise offer a complete explanation of the current understanding of the pathogenesis of OA and practice in imaging and treatments strategies. Contributions from leading scientists provide a detailed introduction in the use of biomarkers in clinical research as well as in clinical practice and OA diagnosis. This book further discusses the potential of regenerative therapies and recent advances in cardiovascular and functional capacity on patients with OA.

Microbiology. --- Osteoarthritis --- Biochemical markers. --- Treatment. --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Biochemistry --- Indicators (Biology) --- Degenerative arthritis --- Degenerative joint disease --- Joint disease, Degenerative --- OA (Disease) --- Old age arthritis --- Osteoarthrosis --- Wear and tear arthritis --- Arthritis --- Microbial biology --- Biology --- Microorganisms --- Medicine --- Immunology --- Osteoimmunology --- Allergology and Rheumatology --- Health Sciences

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Examining tissue residues of contaminants in biota reveals the movement of contaminants within organisms and through food chains as well as the context for understanding and quantifying injuries to organisms and their communities. Yet tissue concentrations of some contaminants are especially challenging to interpret and the ability of today's analytical chemists to provide reliable analytical data of most important environmental contaminants often surpasses the ability of ecotoxicologists to interpret those data.Offering guidance on the ecotoxicologically meaningful interpretation of tissue concentrations, Environmental Contaminants in Biota, Interpreting Tissue Concentrations, Second Edition is updated with current data and new ways of analyzing those data as well as additional contaminants not previously considered. Beginning with a history of wildlife toxicology and data interpretation, chapters cover a wide range of contaminants and their hazardous and lethal concentrations in various animals including DDT, Dioxins, PCBs, and PBDEs in aquatic organisms; methylmurcury, selenium, and trace metals in fishes and aquatic invertebrates; and pharmaceuticals and organic contaminants in marine mammals. The book considers the impact of Polychlorinated Biphenyls, Dibenzo-p-Dioxins and Dibenzofurans, and Polybrominated Diphenyl Ethers; cyclodiene; and other organochlorine pesticides in birds and mammals. Later chapters examine the effects and analysis of lead, cadmium, and radionuclides in biota. With thousands of published research papers reporting tissue concentrations each year, Environmental Contaminants in Biota, Interpreting Tissue Concentrations, Second Edition gives ecotoxicologists the ability to draw actionable value regarding the toxicological consequences of those concentrations and relate tissue concentrations quantitatively to injury: the core of ecotoxicology--

Biological monitoring. --- Histology, Pathological. --- Pollution --- Organisms. --- Environmental aspects. --- Biological organisms --- Biota --- Living organisms --- Life (Biology) --- Species --- Chemical pollution --- Chemicals --- Contamination of environment --- Environmental pollution --- Contamination (Technology) --- Asbestos abatement --- Bioremediation --- Environmental engineering --- Environmental quality --- Factory and trade waste --- Hazardous waste site remediation --- Hazardous wastes --- In situ remediation --- Lead abatement --- Pollutants --- Refuse and refuse disposal --- Histopathology --- Pathological histology --- Histology --- Pathology --- Biologic monitoring --- Biomonitoring (Toxicology) --- Monitoring, Biological --- Poisons --- Toxicology --- Indicators (Biology) --- Environmental aspects --- Analysis

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psychology --- personality --- intelligence --- motivation --- humanities --- Psychology --- Biochemical markers --- Neuropsychiatry --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Biochemistry --- Indicators (Biology) --- Behavioral sciences --- Mental philosophy --- Mind --- Science, Mental --- Human biology --- Philosophy --- Soul --- Mental health --- Psychology. --- Neuropsychiatry. --- Biochemical markers. --- Indonesia. --- Behavioral neurology --- Biological psychiatry --- Neurology --- Industries --- Dutch East Indies --- Endonèsie --- Indanezii͡ --- Indoneshia --- Indoneshia Kyōwakoku --- Indonesi --- Indonesya --- Indonezia --- Indonezii͡ --- Indonezija --- İndoneziya --- İndoneziya Respublikası --- Indūnīsīy --- Induonezėj --- Jumhūrīyah Indūnīsīy --- PDRI --- Pemerintah Darurat Republik Indonesia --- R.I. --- Republic of Indonesia --- Republic of the United States of Indonesia --- Republica d'Indonesia --- Republiek van Indonesi --- Republik Indonesia --- Republik Indonesia Serikat --- Republika Indonezii͡ --- Republika Indonezija --- Rėspublika Indanezii͡ --- RI --- United States of Indonesia --- Yinni --- Indonesia --- Dutch East Indies (Territory under Japanese occupation, 1942-1945) --- Indanezii︠a︡ --- Indonesië --- Indonezii︠a︡ --- Indūnīsīyā --- Induonezėjė --- Jumhūrīyah Indūnīsīyā --- Republiek van Indonesië --- Republika Indonezii︠a︡ --- Rėspublika Indanezii︠a︡