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Cellulase. --- Glycosidases. --- Glycoside hydrolases --- Hydrolases --- Endo-1,4-beta-glucanase --- Glucanase, Endo-1,4-beta --- Glycosidases

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Cellulase. --- Endo-1,4-beta-glucanase --- Glucanase, Endo-1,4-beta --- Glycosidases

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Amylases --- Enzymes --- Amylases. --- Enzymes. --- Biocatalysts --- Ferments --- Soluble ferments --- Diastase --- Ptyalin --- Catalysts --- Proteins --- Enzymology --- Digestive enzymes --- Glycosidases --- Amylolysis --- Animal Biochemistry

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This unique book covers the latest developments in coupling and decoupling of biomolecules containing functionalized carbohydrate components, being one of the first collections in this important area of applied medicinal chemistry. Connecting molecules, often referred as bio-conjugation, has become one of the most often performed procedures in modern medicinal chemistry. Sometimes, when the connected molecules are not useful anymore, they must be disconnected. The molecules that must be connected (coupled) may belong to both small and large molecules and include such constructs as glycoproteins, glycopeptides and glycans. In this work, more than 15 experts address a comprehensive range of potential and current uses of in vitro and in vivo bio-conjugation methodologies, leading to a variety of glycoconjugates. The analytical aspects of bio-conjugation are also here discussed. Medicinal and organic chemists from graduate level onwards will understand the appeal of this important book.

Chemistry. --- Bioorganic chemistry. --- Carbohydrates. --- Medicinal chemistry. --- Biomaterials. --- Medicinal Chemistry. --- Carbohydrate Chemistry. --- Bioorganic Chemistry. --- Clinical chemistry. --- Glycosidases. --- Chemistry, Clinical --- Diagnostic biochemistry --- Diagnostic chemistry --- Medical chemistry --- Biochemistry --- Diagnosis, Laboratory --- Glycoside hydrolases --- Hydrolases --- Biochemistry. --- Biocompatible materials --- Biomaterials --- Medical materials --- Medicine --- Biomedical engineering --- Materials --- Biocompatibility --- Prosthesis --- Bio-organic chemistry --- Biological organic chemistry --- Chemistry, Organic --- Carbs (Carbohydrates) --- Biomolecules --- Organic compounds --- Glycomics --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Composition --- Bioartificial materials --- Hemocompatible materials --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medicinal chemistry --- Pharmacochemistry --- Biomaterials (Biomedical materials)

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Applied biocatalysis and biotransformation, that is, the use of enzymes and whole-cell systems in manufacturing processes for synthetic purposes, has been experiencing a clear boom in recent years, which has led to the start of the so-called “fourth wave”. In fact, the latest advances in bioinformatics, system biology, process intensification, and, in particular, enzyme-directed evolution (encouraged by the 2018 Nobel Prize awarded to F. Arnold), are widening the range of the efficacy of biocatalysts and accelerating the rate at which new enzymes are becoming available, even for activities not previously known. European scientists have been very actively involved in different aspects of this field. Nine contributions dealing with different aspects of applied biocatalysis developed by European researchers are gathered in this Special Issue

biocatalysis --- glycosidases --- isomerases --- Pichia pastoris --- sweeteners --- rare sugars --- cheese whey --- sustainable chemistry --- penicillin acylase --- aculeacin acylase --- N-acyl-homoserine lactone acylases --- quorum quenching --- biofouling --- estolides --- castor oil --- lipase --- candida antarctica lipase A --- Arabidopsis thaliana --- hydroxynitrile lyase --- oxynitrilase --- His-tag --- immobilization --- batch --- continuous flow --- Geobacillus thermocatenolatus --- lipases --- ethanolysis --- ionic liquids --- kinetic resolution --- mandelic acid --- Aspergillus --- fermentation --- filamentous fungi --- genetic engineering --- heterologous expression --- recombinant protein --- secretion --- transcriptional regulation --- n/a --- Halohydrin dehalogenases --- conformational dynamics --- active site tunnels --- molecular dynamics simulations --- omega-3 ethyl esters --- monkfish liver oil --- COSMO-RS --- fungal resting cells --- selectivity --- ketone body ester --- asymmetric synthesis --- configuration inversion