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Among gluten-related disorders, coeliac disease (CD) is the best-known one to date, a chronic immune-mediated enteropathy triggered by exposure to gluten in genetically predisposed individuals. It is a common disease, occurring at all ages and characterized by a wide spectrum of clinical manifestations, affecting any organ or tissue. The diagnosis rate of this pathology has increased in the last 10 years, so worldwide epidemiologic data are now available that show that CD is ubiquitous, with a prevalence of 1.4%, higher in female than male individuals. Currently, the only effective treatment for CD is strict and lifelong adherence to a gluten-free diet (GFD). However, CD research is changing rapidly due to the continuous advancing of knowledge. For this reason, the main goal of this Special Issue has been to address the existing knowledge gaps and help advance such important aspects as the pathophysiology, diagnosis, follow-up, and therapeutic options of this pathology. This Special Issue includes 12 peer-reviewed articles reporting on the latest research findings in and evidence related to CD. The published articles cover a range of topics central to CD and GFDs.

Medicine --- celiac disease --- relatives --- microbiota --- Saccharomyces cerevisiae --- Pseudomonas fluorescens --- Bacteroides caccae --- coeliac disease --- oral diseases --- oral prevention --- gingival bleeding --- sleep-related breathing disorders --- oral health --- enamel defects --- interceptive orthodontics --- data mining gluten free diet --- gluten proteins --- immunogenicity --- evidence-based practice --- case management --- treatment adherence and compliance --- anemia --- iron transporter --- IgA nephropathy --- tissue transglutaminase autoantibody --- tissue transglutaminase-targeted IgA deposits --- flow cytometry --- age --- sex --- lesion grade --- intraepithelial lymphocytes TCRγδ+ --- functional bowel disease --- gluten-free diet --- tissue biomarkers --- non-coeliac gluten sensitivity --- FODMAP diet --- dietitian --- rural health services --- gluten --- gliadin --- gluten immunogenic peptides --- non-dietary therapies --- gluten cross-contaminations --- dietary adherence --- vital gluten --- oat --- hidden gluten --- patients with CD --- symptoms --- gluten excretion urine --- gluten-free diet monitoring --- n/a