Listing 1 - 3 of 3 |
Sort by
|
Choose an application
Biology --- Biologie --- Biology. --- --Biology --- biology --- Biologie moléculaire --- Molecular biology --- Biochimie --- biochemistry --- Cytologie --- cytology --- Évolution --- evolution --- Hérédité --- genetic inheritance --- Génétique --- genetics --- Population animale --- Animal population --- Population végétale --- plant population --- Physiologie --- Physiology --- Écologie --- ecology --- Écosystème --- ecosystems --- 570 --- Cel --- Dieren --- DNA --- Ecologie --- Evolutie --- Genen --- Metabolisme --- Planten --- Testjens --- Biologie ; algemeen --- 57 --- Biological sciences in general --- evolution. --- Biology - textbooks
Choose an application
Autoinflammation, as a relatively new field in clinical rheumatology, has gained an increasing importance in recent years. The number of identified entities and affected patients has gradually increased, and some of the involved pathways have already been identified. This progress allows a deeper understanding of closely linked diseases, namely, inflammasomopathies, interferonopathies, Relo-pathies, and proteasome associated syndromes. These insights have not only improved their classification but also helped to identify new treatment targets of pro-inflammatory cytokines, including IL-1ß, IL-6, interferon-, and TNF-alpha. Nevertheless, there is still a high medical need, especially in reliable outcome measures, for confirmation of data from controlled clinical trials and, finally, also for long-term experience from registers. This issue welcomes all types of papers on the broad spectrum of clinical characteristics, prognosis, pathophysiology, and treatment of autoinflammatory diseases. The goal of this Special Issue is to further raise awareness of autoinflammatory processes and to better separate them from well-established autoimmune diseases. It is clear that we have entered a new age in this complex field, linking rheumatology even closer to immunology.
gout --- febuxostat --- colchicine --- hepatotoxicity --- prophylaxis --- myositis --- inflammatory idiopathic myopathy --- dysphagia --- aspiration --- pneumonia --- immunoglobulin G4-related orbital disease (IgG4-ROD) --- orbital lymphoma (OL) --- computed tomography (CT) --- Hounsfield unit --- imaging --- autoinflammation --- arthritis --- CAPS --- FCAS --- MWS --- CINCA --- NOMID --- hearing loss --- urticarial-like rash --- autoinflammatory disease --- anti-IL-1 treatment --- rheumatoid arthritis --- synovitis --- neoplasms --- edema --- inflammation --- new genetic variant --- monogenic autoinflammatory syndrome --- diagnostic delay --- anakinra --- damage index --- genetic inheritance --- personalized therapy --- Interleukin-1 --- autoinflammatory diseases --- FMF --- coronavirus --- SARS-CoV-2 antibody response --- adult-onset Still’s disease --- autoinflammatory disorder --- systemic-onset juvenile idiopathic arthritis --- haemophagocytic lymphohistiocytosis --- macrophage activation syndrome --- IFN-γ --- JAK inhibitor --- proliferation --- DNA damage repair --- γH2AX --- PBMCs --- T lymphocytes --- proteasome --- autoimmune --- proteasome-associated autoinflammatory syndrome --- therapy --- IL-1 inhibitors --- NGS --- SURF --- spondyloarthritis --- human leukocyte antigen --- undifferentiated enthesitis and/or arthritis --- ASAS classification criteria --- clinical management --- canakinumab --- cytokines --- n/a --- adult-onset Still's disease
Choose an application
Why do humans, uniquely among animals, cooperate in large numbers to advance projects for the common good? Contrary to the conventional wisdom in biology and economics, this generous and civic-minded behavior is widespread and cannot be explained simply by far-sighted self-interest or a desire to help close genealogical kin. In A Cooperative Species, Samuel Bowles and Herbert Gintis--pioneers in the new experimental and evolutionary science of human behavior--show that the central issue is not why selfish people act generously, but instead how genetic and cultural evolution has produced a species in which substantial numbers make sacrifices to uphold ethical norms and to help even total strangers. The authors describe how, for thousands of generations, cooperation with fellow group members has been essential to survival. Groups that created institutions to protect the civic-minded from exploitation by the selfish flourished and prevailed in conflicts with less cooperative groups. Key to this process was the evolution of social emotions such as shame and guilt, and our capacity to internalize social norms so that acting ethically became a personal goal rather than simply a prudent way to avoid punishment. Using experimental, archaeological, genetic, and ethnographic data to calibrate models of the coevolution of genes and culture as well as prehistoric warfare and other forms of group competition, A Cooperative Species provides a compelling and novel account of how humans came to be moral and cooperative.
Cooperation. --- Cooperativeness. --- Behavior evolution. --- Behavioral evolution --- Cooperation (Psychology) --- Collaborative economy --- Cooperative distribution --- Cooperative movement --- Distribution, Cooperative --- Peer-to-peer economy --- Sharing economy --- Evolutionary psychology --- Social psychology --- Economics --- Profit-sharing --- Cooperation --- Cooperativeness --- Behavior evolution --- E-books --- Australia. --- altruism. --- altruistic cooperation. --- altruistic punishment. --- ancestral humans. --- behavior. --- beliefs. --- coevolution. --- common good. --- constraints. --- coordinated punishment. --- correlated equilibrium. --- costly signaling. --- cultural transmission. --- culture. --- early humans. --- equilibrium selection. --- ethical norms. --- evolution. --- evolutionary dynamics. --- fitness-reducing norm. --- fitness. --- folk theorem. --- foragers. --- free-riders. --- free-riding. --- gene-culture coevolution. --- genetic differentiation. --- genetic inheritance. --- group competition. --- group membership. --- guilt. --- helping behavior. --- hostility. --- human cooperation. --- hunter-gatherer society. --- inclusive fitness. --- indirect reciprocity. --- institutions. --- intergroup conflict. --- internalization. --- multi-level selection. --- norms. --- parochial altruism. --- parochialism. --- peer pressure. --- phenotypic expression. --- positive assortment. --- preferences. --- prehistoric human society. --- private information. --- prosocial behavior. --- public goods game. --- public information. --- punishment. --- reciprocal altruism. --- repeated game. --- reproductive leveling. --- sacrifice. --- selective extinction. --- self-interest. --- shame. --- social behavior. --- social dilemmas. --- social emotions. --- social institutions. --- social interactions. --- social norms. --- social order. --- social preferences. --- socialization. --- sociobiology. --- strong reciprocity. --- within-group segmentation.
Listing 1 - 3 of 3 |
Sort by
|