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This 2nd edition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years. As the previous edition, this 2nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2nd edition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field.

Histology. Cytology --- Enzymology --- Human genetics --- medische genetica --- cytologie --- histologie --- enzymen --- DNA. --- Methyltransferases.

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Dit boek is bedoeld voor alle niveaus laboratoriummedewerkers, in opleiding voor of werkzaam op een klinisch chemisch en hematologisch laboratorium. Het boek bevat naast basiskennis ook verdiepingsstof, aangegeven in aparte, blauwe kaders. Deze verdiepingsmaterie is met name geschreven voor het HBO-onderwijs. Op basis van nieuwe ontwikkelingen binnen het vak zijn er in deze derde druk extra paragrafen toegevoegd aan de hoofdstukken 9, 15 en 18. De hoofdstukken zijn op elkaar afgestemd, maar je kunt ze ook afzonderlijk lezen.

Hematologie --- Klinische chemie --- Electrochemistry --- Clinical chemistry --- Pathological haematology --- Fe (ijzer) --- tumoren --- klinische chemie --- laboratoriumdiagnostiek --- biochemie --- Ca (calcium) --- hematologie --- LC (liquid chromatography) --- elektrochemie --- AAS (atomaire absorptie spectrometrie) --- enzymen

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This textbook is designed for students of biology, molecular biology, ecology,medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions.

Organic chemistry --- Enzymology --- General biochemistry --- Biology --- Pathological biochemistry --- Human medicine --- medische biochemie --- organische chemie --- biochemie --- biologie --- biomedische wetenschappen --- enzymen --- Chemistry, Organic. --- Química orgànica

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KEY FEATURES: Contains state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders Includes in-depth discussion of ethical and safety considerations Identifies genetically modified organisms (GMOs) Covers forensic analysis and everyday issues in a diagnostic laboratoryDESCRIPTION:The2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited dise

Macromolecules --- Molecular biology --- Semiology. Diagnosis. Symptomatology --- klinische chemie --- proteomics --- diagnostiek (geneeskunde) --- genomics --- microarrays --- vaccinatie --- electrophoresis --- micro-elektronica --- polymeren --- moleculaire biologie --- enzymen --- Molecular diagnosis. --- Genetic screening. --- Human chromosome abnormalities --- Medical screening --- Diagnosis --- Molecular diagnostics --- Molecular aspects

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The Role of Catalysis for the Sustainable Production of Bio-fuels and Bio-chemicals describes the importance of catalysis for the sustainable production of biofuels and biochemicals, focused primarily on the state-of-the-art catalysts and catalytic processes expected to play a decisive role in the ""green"" production of fuels and chemicals from biomass. In addition, the book includes general elements regarding the entire chain of biomass production, conversion, environment, economy, and life-cycle assessment. Very few books are available on catalysis in production schemes us

General biochemistry --- Industrial chemistry --- Biotechnology --- katalyse --- katalysatoren --- biomassa --- H (waterstof) --- biobrandstoffen --- biodiesel --- hernieuwbare energie --- witte biotechnologie --- groene chemie --- groene biotechnologie --- biorefinery --- biochemie --- groene economie --- biotechnologie --- duurzame ontwikkeling --- enzymen --- chemische processen --- Biomass energy. --- Catalysis.