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Regenerative medicine and tissue engineering play significant roles in the treatment of currently intractable conditions, such as chronic heart failure, stroke, chronic osteoarthritis, and other maladies. Regenerative medicine and tissue engineering generally depend on the utilization of stem cells to treat patients but may also utilize mature cells that would not normally be considered as stem cells (e.g., skin). Stem cells (like mature cells) may be obtained from many sources in the body including bone marrow, cord blood, cord tissue, adipose tissue, etc. Although stem cells are often used in therapy immediately upon isolation, in many circumstances, the stem and progenitor cells will be harvested, processed and banked frozen until a later time. Biobanking is a convenient alternative to same-day therapeutic use, in that it allows for patient recovery (e.g., from liposuction), provides time to identify the best treatment options, and may allow for multiple interventions with additional patient inconvenience or risk.

Medicine. --- n/a --- MSCs --- EVs --- exosomes --- tissue regeneration --- immunomodulation --- biobanking --- adult stem cells --- ground-state --- autologous transplantation --- regenerative medicine --- stem cell banking --- newborn stem cells --- perinatal stem cells --- umbilical cord tissue --- umbilical cord blood --- placenta --- Vascular tissue engineering --- human cord blood-derived endothelial cells --- endothelialization --- vascular graft --- Munich Vascular Biobank --- atherosclerosis --- human vascular tissue --- RIN --- RNA fragmentation --- adipose tissue --- cryopreservation --- autologous --- fat grafting --- cryogenic storage --- lipoaspirate --- cosmetic surgery