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This book provides a resource for the science or medical professional interested in islet biology. With a mix of review articles and studies showing primary data, new advances in islet inflammation and metabolic homeostasis are highlighted. The topics are succinctly presented by distinct viewpoints. An introduction to the Special Issue, with summaries of the studies included, is provided by the Guest Editors.

beta cell death --- beta cell dysfunction --- beta cell failure --- ER stress --- hyperglycemia --- obesity --- oxidative stress --- saturated fatty acids --- beta cell hypofunction --- beta cell hyperfunction --- glucolipotoxicity --- low carbohydrate diet --- ketogenic diet --- insulin sensitivity --- pancreas --- islet of Langerhans --- proinflammatory cytokines --- NADPH oxidases --- Rac1 --- pancreatic beta cell --- diabetes --- β-cell --- macrophage --- islet --- cytokine --- insulin --- transcriptomics --- type 2 diabetes --- insulin resistance --- inflammation --- gut microbiome --- untargeted plasma metabolomics --- polyunsaturated fatty acids --- prostaglandins --- insulin secretion --- beta-cell function --- n/a