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Vitamin E is a group of fat-soluble compounds found in a wide variety of foods. Daily requirements of vitamin E can be met with a balanced diet. High-dose supplementation may be hazardous rather than beneficial. Vitamin E serves as an antioxidant, participates in anti-inflammatory processes, inhibits platelet aggregation, and enhances immunity. Vitamin E supplementation can be beneficial against coronary artery disease, eye disorders, cognitive decline, cancer, and skin aging. This book will mainly focus on the diverse functions of vitamin E, importance of vitamin E status to provide a healthy lifespan, and the interaction between vitamin E and several pathological conditions. Readers will receive a general overview of the importance of vitamin E in health and different pathological conditions.
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In this book, Vitamin E in Health and Disease, the chapter by Dr Lisa Schmölz et al., The Hepatic Fate of Vitamin E, includes the hepatic metabolism of vitamin E, its storage, release, distribution, and its effects on the metabolism in great detail, as well as its effect on the prevention of diseases, in addition to its role in anti-aging. The chapter by Dr Rusu Anca Elena reports on the effect of vitamin E in patients with hemodialysis. In a similar manner, the chapter of Drs Rayan Ahmed and Paul W. Sylvester describe g-Tocotrienol, a natural isoform within the vitamin E family of compounds, which displays potent antiproliferative, apoptotic and reversal of epithelial-to-mesenchymal-transition activity against breast cancer, employing treatment doses that have little or no effect on normal cell viability. The chapter by Milka Mileva and Angel S. Galabov describes how vitamin E could be recommended as a reliable agent, indeed as a component in multiorgan flu therapy. Last, Dr Juan José Godina-Nava et al. describe the cytoprotector effect of the 120-Hz electromagnetic fields in early hepatocarcinogenesis.
Vitamin E. --- Tocopherol --- Isopentenoids --- Vitamins, Fat-soluble --- Life Sciences --- Vitaminology --- Genetics and Molecular Biology --- Alimentology --- Biochemistry
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Vitamin E --- Tocopherol --- Isopentenoids --- Vitamins, Fat-soluble --- Physiological effect. --- Therapeutic use.
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In this book, the authors present topical research in the study of the daily requirements, dietary sources and symptoms of deficiency relating to vitamins A and E. Topics discussed include clinical use studies, medicinal and dietary aspects, and the dietary sources and health consequences of vitamins A and E. Other topics include indigenous vegetables as an excellent source of vitamin A; dietary vitamin E intake by older Japanese adults; vitamin A and other biochemical markers in obese patients with biliopancreatic bypass; and the role of vitamin E in dementia.
Vitamin A. --- Vitamin E. --- Tocopherol --- Isopentenoids --- Vitamins, Fat-soluble --- Retinol --- Carotenes --- Retinoids --- Beta carotene --- Retinal (Visual pigment)
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Biology --- Antioxidants --- Free Radicals --- Free radicals (Chemistry) --- Antioxydants --- Radicaux libres (Chimie) --- Periodicals. --- Periodicals --- Périodiques --- Vitamin C --- Vitamin E --- Antioxidants. --- Biochemistry. --- Free Radicals. --- Vitamin C. --- Vitamin E. --- Radicalen (chemie) --- Radicals, Free --- Free Radical Scavengers --- Reactive Oxygen Species --- Anti-Oxidant Effect --- Anti-Oxidant Effects --- Antioxidant Effect --- Antioxidant Effects --- Anti Oxidant Effect --- Anti Oxidant Effects --- Effect, Anti-Oxidant --- Effect, Antioxidant --- Effects, Anti-Oxidant --- Effects, Antioxidant --- Food Preservatives --- Oxidation-Reduction --- Preservatives, Pharmaceutical --- Oxidants --- Chemistry --- Health Sciences --- Life Sciences --- General and Others --- Toxicology --- Pathology --- Cytology, Cell Biology --- Oxygen Radical Absorbance Capacity --- Anti-Oxidants --- Anti Oxidants --- Biologie --- Free Radical --- Radical, Free --- Anti-Oxidant --- Antioxidant --- Antioxidant Activity --- Activity, Antioxidant --- Anti Oxidant --- Free radical reactions --- Free radical reactions. --- Réactions radicalaires
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Antioxidants --- Free Radicals --- periodicals --- Free radicals (Chemistry) --- Vitamin C --- Vitamin E --- Antioxidants. --- Biochemistry. --- Free Radicals. --- Vitamin C. --- Vitamin E. --- Radicalen (chemie) --- Histology. --- Microbiology. --- Tocopherol --- Ascorbic acid --- Anti-Oxidant Effect --- Anti-Oxidant Effects --- Antioxidant Effect --- Antioxidant Effects --- Anti Oxidant Effect --- Anti Oxidant Effects --- Effect, Anti-Oxidant --- Effect, Antioxidant --- Effects, Anti-Oxidant --- Effects, Antioxidant --- Radicals, Free --- Isopentenoids --- Vitamins, Fat-soluble --- Hydroxy acids --- Vitamins, Water-soluble --- Radicals (Chemistry) --- Free radical reactions --- Chemical inhibitors --- Oxygen Radical Absorbance Capacity --- Food Preservatives --- Oxidation-Reduction --- Preservatives, Pharmaceutical --- Oxidants --- Free Radical Scavengers --- Reactive Oxygen Species --- Anti-Oxidants --- Anti Oxidants --- Biochemistry --- Anti-Oxidant --- Antioxidant --- Antioxidant Activity --- Activity, Antioxidant --- Anti Oxidant --- Free Radical --- Radical, Free
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This comprehensive volume examines the role of vitamin E as an essential micronutrient in human health and its extensive clinical benefits. Sections cover a wide breadth of topics, including vitamin E intake and recommended daily allowance, understanding the biological activities of Vitamin E and observed physiological effects, benefits of vitamin E on upper respiratory infections, cardiovascular disease, age-related macular degeneration, Alzheimer’s disease, and intake safety. The text serves to emphasize the importance of vitamin E in relation to disease prevention as well as to raise awareness of the number of health conditions where an increased intake of vitamin E can be of potential significance. It explores vitamin E in an up-to-date, science based, applicable real-life perspective and offers pragmatic solutions for its safe and personalized use beyond the various methodological and statistical controversies. Intended for the medical and nutritional community, Vitamin E in Human Health will not only be an expansive resource for healthcare professionals, but also makes efforts to stimulate increased support for vitamin E research and further exploration of the safe and efficacious use for this essential micronutrient. .
Vitamin E. --- Tocopherol --- Isopentenoids --- Vitamins, Fat-soluble --- Personal health and hygiene. --- Nutrition. --- Food science. --- Clinical Nutrition. --- Food Science. --- Science --- Alimentation --- Food --- Nutrition --- Health --- Physiology --- Diet --- Dietetics --- Digestion --- Food habits --- Malnutrition --- Health aspects --- Clinical nutrition. --- Nutrition . --- Food—Biotechnology. --- Clinical nutrition --- Diet and disease --- Dietotherapy --- Medical nutrition therapy --- MNT (Medical nutrition therapy) --- Nutrition therapy --- Therapeutics, Physiological --- Therapeutic use
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Nutrition is a key element that has the potential to reduce bone loss and fracture risk. While nutrition has become one of many variables that can impact bone health, there is a need to formulate and maintain nutritional approaches and techniques for the prevention and treatment of bone health-associated disorders that may affect women's health. This book, compiling articles published during 2021–2022, belongs to the Topical Collection " Nutrition and Women Bone Health". The application of the knowledge presented here may subsequently provide further support for preventive approaches based on population-based interventions. Key major topics related to the relationship between different nutrients and women's bone health are discussed using high-quality research methodologies, including randomized clinical trials and observational studies, all of which are led by notable nutritional and clinical researchers. The Guest Editor intends for this book to contribute to expanding the body of knowledge on bone health and nutrition in women as well as highlight the pivotal role that this interaction plays in human health throughout populations. The findings represent a beginning point for future research, which should progressively be focused on experimental investigations with diverse populations and demographic groups in order to further understand the link between nutrition and bone health in women.
bone mass --- dietary total antioxidant capacity --- KNHANES --- menopause --- osteoporosis --- fatty acids --- n-3 PUFAs --- bone mineral density --- postmenopause --- botanicals --- herbs --- postmenopausal women --- vitamin D --- bone remodeling --- cheese --- enriched dairy --- vitamin E --- bone turnover --- osteopenia --- tocopherol --- bone marker turnover --- bone health --- n/a
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The metabolomics approach, defined as the study of all endogenously-produced low-molecular-weight compounds, appeared as a promising strategy to define new cancer biomarkers. Information obtained from metabolomic data can help to highlight disrupted cellular pathways and, consequently, contribute to the development of new-targeted therapies and the optimization of therapeutics. Therefore, metabolomic research may be more clinically translatable than other omics approaches, since metabolites are closely related to the phenotype and the metabolome is sensitive to many factors. Metabolomics seems promising to identify key metabolic pathways characterizing features of pathological and physiological states. Thus, knowing that tumor metabolism markedly differs from the metabolism of normal cells, the use of metabolomics is ideally suited for biomarker research. Some works have already focused on the application of metabolomic approaches to different cancers, namely lung, breast and liver, using urine, exhaled breath and blood. In this Special Issue we contribute to a more complete understanding of cancer disease using metabolomics approaches.
cell transporters --- pharmacodynamics --- cell growth --- in vitro study --- metabolomic signatures --- endometabolome --- lung cancer --- metabolomics --- chemometric methods --- bladder cancer --- mTOR --- metabolite profiling --- metabolic pathways --- hepatocellular carcinoma --- glutamate --- senescence MCF7 --- breath analysis --- bio actives --- biomarker --- gas chromatography–mass spectrometry (GC–MS) --- GC-MS --- lung --- omics --- nutraceuticals --- glutaminase --- metabolism --- acylcarnitines --- Erwinaze --- Kidrolase --- glutathione --- targeted metabolomics --- apoptosis --- SLC1A5 --- essential amino acids --- cancer progression --- ASCT2 --- HR MAS --- alanine --- analytical platforms --- volatile organic compound --- glutaminolysis --- isotope tracing analysis --- asparaginase --- vitamin E --- breast cancer --- prognosis --- early diagnosis --- tocotrienols --- NMR --- prostate cancer --- in vitro --- cancer --- MDA-MB-231
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The recognition of the exceptional chemical and biological properties of vanadium compounds has led, in recent decades, to extensive research exploring their chemistry, biochemistry, and medicinal chemistry. Due to the prospective application of vanadium compounds as therapeutic agents against diseases such as diabetes, cancer and those provoked by parasites and bacteria, vanadium coordination chemistry and biochemistry has been an area of extensive research. Currently, the most promising potential uses of vanadium compounds are as nutritional supplements and as anticancer agents potentiated by immunotherapy. Nevertheless, researchers from all over the world are dedicating their efforts to vanadium research related to other potential therapeutic applications of vanadium compounds and to obtain insights into their beneficial effects on health and their modes of action. This Special Issue collected research contributions focused on recent advances in vanadium chemistry, biochemistry, and medicinal chemistry. I expect that this collection will have a great impact on the future direction of vanadium research.
Research & information: general --- Chemistry --- Inorganic chemistry --- polyoxometalates --- decavanadate --- cytotoxicity --- insulin-like activity --- diabetes therapy --- vanadium biochemistry --- vanadium speciation --- vanadium --- proteins --- DNA --- fluorescence --- binding constants --- mechanism of action --- oxidovanadium(V) --- vanadium Schiff base coordination complex --- low acute toxicity --- Oxidovanadium(V) --- Schiff base --- X-ray crystallography --- DNA interaction --- 2-aminopyrimidinium --- experimental and theoretical characterization --- DFT --- docking RNA/DNA --- vitamin E --- EPR --- tocopherol --- 51V NMR --- urethane --- aerosol delivery --- lung cancer --- apoptosis --- antineoplastic --- oxidovanadium(IV) phenantrholine chrysin --- vanadium cellular uptake --- anticancer --- albumin interaction --- glycosylated flavonoid --- oxidovanadium(IV) complex --- antitumoral --- antioxidant --- cell signaling --- cancer --- anticancer agents --- n/a
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