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With a new foreword by Nora Volkow, Director of the National Institute on Drug Abuse, this second edition of Office-Based Buprenorphine Treatment of Opioid Use Disorder provides updated information on evidence-based treatment for opioid use disorder (OUD)—an increasingly important topic as the epidemic of opioid misuse and overdose deaths grows in the United States. Bulleted clinical pearls at the end of each chapter, as well as specific clinical recommendations and detailed case discussions throughout, make it easier for readers to retain knowledge and integrate it into their clinical practice. The guide also features sample documentation and scales, including a treatment contract and a patient consent, that can be used to model documents in practice. This new edition of Office-Based Buprenorphine Treatment has been updated to reflect DSM-5 language, and two additional chapters have been included: one that addresses other pharmacotherapies useful in treating OUD, including methadone and naltrexone, and another that discusses OUD treatment specifically with regard to women’s health and pregnancy. A discussion of the Comprehensive Addiction and Recovery Act (CARA). Advice for working with Alcoholics Anonymous and Narcotics Anonymous. A discussion on integrating buprenorphine into residential and inpatient opioid treatment programs. -- Publisher

Opioid abuse --- Buprenorphine --- Analgesics --- Morphine --- Narcotic antagonists --- Opioid addiction --- Opioid habit --- Drug abuse --- Chemotherapy. --- Therapeutic use. --- Derivatives --- Opioid-Related Disorders --- Opiate Substitution Treatment. --- Medication Assisted Treatment of Opioid --- Opiate Medication-Assisted Treatment --- Opioid Medication Assisted Treatment --- Opioid Replacement Therapy --- Opioid Substitution Therapy --- Opioid Substitution Treatment --- Opiate Replacement Therapy --- Medication-Assisted Treatment, Opiate --- Opiate Medication Assisted Treatment --- Opiate Medication-Assisted Treatments --- Opiate Replacement Therapies --- Opiate Substitution Treatments --- Opioid Replacement Therapies --- Opioid Substitution Therapies --- Opioid Substitution Treatments --- Replacement Therapy, Opiate --- Replacement Therapy, Opioid --- Substitution Therapy, Opioid --- Substitution Treatment, Opiate --- Substitution Treatment, Opioid --- Therapy, Opioid Substitution --- Methadone --- 6029-M --- Buprenex --- Buprenorphine Hydrochloride --- Buprex --- Prefin --- RX-6029-M --- Subutex --- Temgesic --- Temgésic --- 6029 M --- 6029M --- Hydrochloride, Buprenorphine --- RX 6029 M --- RX6029M --- Opiate Substitution Treatment --- Addiction, Opioid --- Dependence, Opioid --- Opiate Abuse --- Opioid Abuse --- Opioid Addiction --- Opioid Dependence --- Opiate Addiction --- Opiate Dependence --- Abuse, Opiate --- Abuse, Opioid --- Abuses, Opiate --- Abuses, Opioid --- Addiction, Opiate --- Addictions, Opioid --- Dependence, Opiate --- Dependences, Opioid --- Opiate Abuses --- Opioid Abuses --- Opioid Addictions --- Opioid Dependences --- Opioid Related Disorders --- Opioid-Related Disorder --- Analgesics, Opioid --- Narcotics --- Opioid Maintenance Treatment --- Maintenance Treatment, Opioid --- Opioid Maintenance Treatments --- Treatment, Opioid Maintenance --- Opioid Misuse --- Opioid Use Disorder --- Prescription Opioid Abuse --- Prescription Opioid Misuse --- Abuse, Prescription Opioid --- Disorder, Opioid Use --- Misuse, Opioid --- Misuse, Prescription Opioid --- Opioid Abuse, Prescription --- Opioid Misuses --- Opioid Use Disorders --- Prescription Opioid Abuses --- Prescription Opioid Misuses --- drug therapy. --- therapeutic use. --- drug therapy --- therapeutic use

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"Confronting the Drug Control Establishment is a biography of Alfred R. Lindesmith and an intellectual history of his times. A sociologist at Indiana University, Lindesmith believed legal prohibition of addictive drugs was futile and wrote widely on the threat to democracy inherent in such a policy." "Throughout his life Lindesmith attempted to utilize his research for the creation of more rational and humane drug control laws. His consistent message was that the addict's self-concept is a central element in human addiction. Lindesmith felt that an overriding influence on an addict's self-concept is a fear of withdrawal, which keeps an addict from seeking treatment and becomes a key driving force in the drug problem."--BOOK JACKET.

Opium abuse. --- Social psychologists --- Sociologists --- Drug legalization --- Drug and Narcotic Control --- Opioid-Related Disorders. --- Psychology, Social --- Sociology --- Opium abuse --- Sociology & Social History --- Social Sciences --- Social Change --- Psychologists --- Opium addiction --- Opium habit --- Drug abuse --- Drug Control --- Narcotic and Drug Control --- Pharmaceutic Policy --- Drug Regulations --- Narcotic Control --- Pharmaceutical Policy --- Control, Drug --- Control, Narcotic --- Controls, Drug --- Controls, Narcotic --- Drug Controls --- Drug Regulation --- Narcotic Controls --- Pharmaceutical Policies --- Policies, Pharmaceutical --- Policy, Pharmaceutical --- Regulation, Drug --- Regulations, Drug --- Substance-Related Disorders --- Decriminalization of illegal drugs --- Drug decriminalization --- Legalization of illegal drugs --- Decriminalization --- Narcotic laws --- General Social Development and Population --- Psychology, Perceptual --- Social Psychology --- Perceptual Psychology --- Addiction, Opioid --- Dependence, Opioid --- Opiate Abuse --- Opioid Abuse --- Opioid Addiction --- Opioid Dependence --- Opiate Addiction --- Opiate Dependence --- Opioid Misuse --- Opioid Use Disorder --- Prescription Opioid Abuse --- Prescription Opioid Misuse --- Abuse, Opiate --- Abuse, Opioid --- Abuse, Prescription Opioid --- Addiction, Opiate --- Dependence, Opiate --- Disorder, Opioid Use --- Misuse, Opioid --- Misuse, Prescription Opioid --- Opiate Abuses --- Opioid Abuse, Prescription --- Opioid Abuses --- Opioid Addictions --- Opioid Dependences --- Opioid Misuses --- Opioid Related Disorders --- Opioid Use Disorders --- Opioid-Related Disorder --- Prescription Opioid Abuses --- Prescription Opioid Misuses --- Analgesics, Opioid --- Lindesmith, Alfred Ray, --- Lindesmith, Alfred Ray --- United States --- Biography --- Social psychologists - United States - Biography.

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Methadone and buprenorphine are the only two opioids that are indicated for the management of both pain and opioid-related drug addiction.  Both present unique challenges to the general practitioner and pain specialist, requiring a separate analysis from the rest of the drugs in the same family.  Handbook of Methadone Prescribing and Buprenorphine Therapy is an invaluable guide to the safe use of these opioids.  Authored by clinical and academic leaders from a variety of settings and backgrounds, this book includes chapters on pharmacology, adverse effects, safe rotation from other opioids, cardiac toxicity, prescribing, pharmacokinetics, equianalgesic dose, and replacement therapy. This comprehensive text provides clinicians, researchers, policy-makers and academicians a resource for all the relevant points in methadone prescribing and buprenorphine therapy.

Buprenorphine -- Handbooks, manuals, etc. --- Drugs -- Prescribing -- Handbooks, manuals, etc. --- Methadone maintenance -- Handbooks, manuals, etc. --- Methadone maintenance --- Ketones --- Substance-Related Disorders --- Therapeutics --- Morphinans --- Neurologic Manifestations --- Analgesics --- Diseases --- Nervous System Diseases --- Opiate Alkaloids --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Sensory System Agents --- Organic Chemicals --- Alkaloids --- Chemicals and Drugs --- Peripheral Nervous System Agents --- Heterocyclic Compounds --- Physiological Effects of Drugs --- Pharmacologic Actions --- Chemical Actions and Uses --- Buprenorphine --- Pain --- Drug Therapy --- Analgesics, Opioid --- Opiate Substitution Treatment --- Methadone --- Opioid-Related Disorders --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Pathology --- Anesthesiology --- Methadone maintenance. --- Buprenorphine. --- Methadone hydrochloride --- Methadone treatment programs --- Therapeutic use --- Medicine. --- Anesthesiology. --- Internal medicine. --- Oncology. --- Neurology. --- Pain medicine. --- Rehabilitation medicine. --- Medicine & Public Health. --- Pain Medicine. --- Rehabilitation Medicine. --- Internal Medicine. --- Morphine --- Narcotic antagonists --- Drug abuse --- Derivatives --- Treatment --- Rehabilitation. --- Oncology  . --- Tumors --- Medicine, Internal --- Anaesthesiology --- Surgery --- Nervous system --- Neuropsychiatry --- Algiatry --- Neurology . --- Medicine, Rehabilitation --- Rehabilitation medicine --- Rehabilitation --- Medicine, Physical

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In 1988, Gavril W. Pasternak published the first edition of this seminal text. It was a lucid account of the latest knowledge on opiate receptors and related receptor subtypes, a then controversial field, providing an integrated approach correlating the biochemical, physiological, and pharmacological aspects of opiate reaction. Fully revised and expanded, The Opiate Receptors, 2nd edition presents all the advances made in the field in the past twenty years. It covers a wide variety of topics including, but not limited to, the following: pharmacology of opioid drugs; endogenous opioids; molecular biology of mu receptors; molecular biology of delta receptors; kappa opioid receptor gene and the regulatory mechanisms of its protein expression; opioid receptor signal transduction mechanisms; mu opioid receptor mediated analgesia and reward; kappa opioid receptor function; delta opioid receptor function; genetics of opioid receptor functions in mice; opioid receptor trafficking; opioid receptor dimerization; molecular modulation of in vivo tolerance; and genetics of opioid actions. Written by leading international researchers in the field, this new edition is as groundbreaking and vital as its predecessor.

Endorphins -- Receptors. --- Endorphins. --- Opioids -- Receptors. --- Opioids. --- Receptors. --- Endorphins --- Opioids --- Receptors, Neuropeptide --- Biological Science Disciplines --- Opioid Peptides --- Receptors, G-Protein-Coupled --- Peptides --- Neuropeptides --- Receptors, Neurotransmitter --- Receptors, Cell Surface --- Receptors, Peptide --- Natural Science Disciplines --- Amino Acids, Peptides, and Proteins --- Nerve Tissue Proteins --- Disciplines and Occupations --- Membrane Proteins --- Chemicals and Drugs --- Proteins --- Receptors, Opioid --- Physiology --- Human Anatomy & Physiology --- Medicine --- Health & Biological Sciences --- Animal Biochemistry --- Neurology --- Receptors --- Opioid receptors --- Endorphin receptors --- Morphine receptors --- Narcotic receptors --- Opiate receptors --- Medicine. --- Neurosciences. --- Biomedicine. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system

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The possibility that morphine and other opioids may modulate tumour growth and metastasis has been researched for many years. The recent past has seen multiple clinical studies attempting to document whether limiting the perioperative use of morphine is beneficial for cancer surgery patients. Furthermore, a lot of exciting new data has been generated in vitro, but also in preclinical and clinical studies, that indirectly shed light on the effect of opioids on cancer. This book combines chapters written by qualified experts around the world whose research encompasses the effect of morphine or other opioids on tumour growth and metastasis. This includes clinicians, researchers working on animal models and studying the effect of morphine on tumours, and most importantly the mechanism for this effect, and lastly cell biologists. Current investigations and cross talk between basic science and clinical trials will refine our understanding of the multiple levels of actions of morphine and other opioids on tumour growth and metastasis, and result in improved guidelines for patient care. This book will be of interest to clinicians, especially those dealing with cancer patients and their pain management, as well as students, teachers and scientists in the fields of anaesthesiology, oncology, tumour biology, immunology, opioid pharmacology.

Morphine -- Therapeutic use. --- Morphine. --- Opioids. --- Metastasis --- Growth Substances --- Therapeutics --- Morphinans --- Biological Science Disciplines --- Neoplastic Processes --- Neoplasms --- Phenanthrenes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pathologic Processes --- Opiate Alkaloids --- Natural Science Disciplines --- Heterocyclic Compounds with 4 or More Rings --- Heterocyclic Compounds, Bridged-Ring --- Physiological Effects of Drugs --- Heterocyclic Compounds --- Pathological Conditions, Signs and Symptoms --- Disciplines and Occupations --- Diseases --- Pharmacologic Actions --- Polycyclic Hydrocarbons, Aromatic --- Alkaloids --- Chemicals and Drugs --- Chemical Actions and Uses --- Polycyclic Compounds --- Morphine --- Growth Inhibitors --- Pharmacology --- Neoplasm Metastasis --- Drug Therapy --- Medicine --- Health & Biological Sciences --- Oncology --- Metastasis. --- Cancer --- Chemotherapy. --- Cancer metastasis --- Dissemination of cancer --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Morphia --- Dissemination --- Medicine. --- Pharmacy. --- Cancer research. --- Pharmacology. --- Oncology. --- Pain medicine. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Pain Medicine. --- Antineoplastic agents --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Narcotics --- Opium --- Treatment --- Toxicology. --- Oncology  . --- Tumors --- Chemicals --- Poisoning --- Poisons --- Chemistry --- Drugs --- Materia medica --- Toxicology --- Algiatry --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Pharmacy --- Cancer research --- Physiological effect