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Brain norepinephrine
Authors: --- ---
ISBN: 9780511544156 9780521834919 9781107407411 9780511275081 0511275080 0511274386 9780511274381 0511272766 9780511272769 051127355X 9780511273551 0521834910 0511544154 1107407419 1107161169 1280815329 9786610815326 0511320868 Year: 2007 Publisher: Cambridge New York Cambridge University Press

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Abstract

This book was first published in 2007. Norepinephrine is a chemical neurotransmitter. Drugs that directly manipulate central nervous system (CNS) norepinephrine are being developed targeting noradrenergic neurons to deliver therapeutic effects. Noradrenergic drugs have been proven effective for depression and ADHD, and new disease indications are being identified. A team of experts provides the reader with a thorough understanding of the anatomy, physiology, molecular biology, pharmacology and therapeutics of norepinephrine in the brain, including an extensive review of the role of norepinephrine in brain diseases. The book is divided into four sections: the basic biology of norepinephrine; the role that norepinephrine plays in behavior; evidence of norepinephrine's role in CNS diseases, and the pharmacology and therapeutics of noradrenergic drugs in the treatment of psychiatric and neurological disorders.


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Noradrenergic signaling and astroglia
Authors: ---
ISBN: 9780128134269 0128134267 0128050888 9780128050880 Year: 2017 Publisher: London, England : Academic Press,

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"Noradrenergic Signaling and Astroglia integrates what is known about the active role of astroglia in the locus coeruleus-noradrenergic system and outlines the most recent advances in the field. It discusses the molecular mechanisms underlying norepinephrine-induced receptor activation in astroglia, cellular metabolism and CNS energy provision, in vitro, ex vivo, and in vivo models, gliosignalling and neuronal activity, and astroglial networks, gap junctions, and morphological plasticity. The book also addresses the role of astroglial adrenergic receptor activation in memory formation, cognition, regulation of sleep homeostasis, and lastly in neurological disorders, including trauma (cellular edema), neurodegeneration (Alzheimer's disease), and neuroinflammation (multiple sclerosis). Noradrenergic Signaling and Astroglia is a valuable source of new knowledge for a wide audience, including graduate students, post-doctoral fellows, and researchers in neuroscience, life sciences, and the biological and biomedical sciences"--


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Biochemistry and histocytochemistry research developments
Authors: ---
ISBN: 1616689323 9781616689322 1608762831 9781608762835 Year: 2010 Publisher: New York

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