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This book is a philosophical analysis of the development and production of the anti-diphtheria serum in France from 1894 to 1900. Jonathan Simon's unique approach considers serum, a medicinal drug, as a technological object and analyzes its insertion into the therapeutic environment of diphtheria.
Diphtheria --- Serotherapy --- History
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Corynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects.
Corynebacterium diphtheriae. --- Diphtheria toxin. --- Bacillus diphtheriae --- Klebs-Loeffler bacillus --- Medicine. --- Medical microbiology. --- Parasitology. --- Epidemiology. --- Bacteriology. --- Microbial genetics. --- Microbial genomics. --- Biomedicine. --- Medical Microbiology. --- Microbial Genetics and Genomics. --- Bacterial toxins --- Corynebacterium --- Microbiology. --- Medical parasitology. --- Genomics --- Microbial genetics --- Microorganisms --- Genetics --- Microbiology --- Human beings --- Human parasitology --- Medical sciences --- Parasitology --- Parasitic diseases --- Diseases --- Public health --- Microbial biology --- Biology --- Parasites
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