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Structural and Functional Relationships in Prokaryotes
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ISBN: 0387271252 0387207082 Year: 2005 Publisher: New York, NY : Springer New York : Imprint: Springer,

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Abstract

This new textbook on bacterial physiology is aimed at senior level students pursuing a one-semester course in the biology or microbiology curriculum. The text takes a balanced view of prokaryotic physiology, discussing both bioenergetics and bacterial metabolism in a way that establishes general principles and concepts and emphasizes throughout the information gained from model systems. The book also covers some experimental design issues, giving students an appreciation of the practical aspects and consequences of bacterial metabolism. It also stimulates students’ interests in future developments in the field by including discussions by five world-famous bacterial physiologists about future developments in the field.


Periodical
HPB.
Author:
ISSN: 14772574 Year: 1999 Publisher: [London] : Isis Medical Media

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Keywords

Liver --- Biliary tract --- Pancreas --- Liver Diseases. --- Pancreatic Diseases. --- Biliary Tract Diseases. --- Diseases --- Diseases. --- Gastroenterology. --- Hepatology. --- Bilious diseases and biliousness --- Hepatology --- Biliary Tract Disease --- Disease, Biliary Tract --- Diseases, Biliary Tract --- Tract Disease, Biliary --- Tract Diseases, Biliary --- Disease, Pancreatic --- Diseases, Pancreatic --- Pancreatic Disease --- Liver Dysfunction --- Disease, Liver --- Diseases, Liver --- Dysfunction, Liver --- Dysfunctions, Liver --- Liver Disease --- Liver Dysfunctions --- Biliary tree --- Liver Diseases --- Pancreatic Diseases --- Biliary Tract Diseases --- Gastroenterology --- Digestive organs --- Endocrine glands --- Exocrine glands --- Bile --- Abdomen --- Pàncrees. --- Fetge. --- Bilis. --- Gastroenterologia. --- Malalties del pàncrees. --- Malalties del fetge. --- Hepatopaties --- Malalties hepàtiques --- Hepatologia --- Cirrosi hepàtica --- Hepatitis --- Hepatitis B --- Hepatitis vírica --- Hepatopaties alcohòliques --- Insuficiència hepàtica --- Síndrome de Budd-Chiari --- Fibrosi quística --- Hipoglucèmia --- Pancreatitis --- Medicina interna --- Aparell digestiu --- Gastroenterologia pediàtrica --- Proctologia --- Tracte gastrointestinal --- Malalties de l'aparell digestiu --- Fel --- Digestió --- Humors corporals --- Àcids biliars --- Pigments biliars --- Fetge --- Tracte biliar --- Cèl·lules hepàtiques --- Bilis --- Cirurgia hepàtica --- Illots de Langerhans


Book
The First Cell : The Mystery Surrounding the Beginning of Life
Authors: ---
ISBN: 3030453812 3030453804 Year: 2020 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Abstract

This book introduces a fresh perspective on the conditions for the genesis of the first cell. An important possible environment of the prehistoric Earth has long been overlooked as a host to the perfect biochemical conditions for this process. The first complexes of continental crust on the early Earth must have already contained systems of interconnected cracks and cavities, which were filled with volatiles like water, carbon dioxide and nitrogen. This book offers insights into how these conditions may have provided the ideal physical and chemical setting for the formation of protocells and early stages of life. The authors support their hypothesis with a number of astonishing findings from laboratory experiments focusing on a variety of organic compounds, and on the formation of key cellular ingredients and of primitive cell-like structures. Moreover, they discuss the principles of prebiotic evolution regarding the aspects of order and complexity. Guiding readers through various stages of hypotheses and re-created evolutionary processes, the book is enriched with personal remarks and experiences throughout, reflecting the authors' personal quest to solve the mystery surrounding the first cell.

Keywords

Life --- Origin. --- Abiogenesis --- Biogenesis --- Germ theory --- Heterogenesis --- Life, Origin of --- Life (Biology) --- Origin of life --- Plasmogeny --- Plasmogony --- Evolution (Biology) --- Exobiology --- Spontaneous generation --- Origin --- Biochemistry. --- Life sciences. --- Geology. --- Cell physiology. --- Biochemistry, general. --- Popular Life Sciences. --- Cell Physiology. --- Cell function --- Cytology --- Physiology --- Geognosy --- Geoscience --- Earth sciences --- Natural history --- Biosciences --- Sciences, Life --- Science --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Composition --- Ciències de la vida --- Cèl·lules --- Biologia --- Fisiologia --- Reproducció --- Astròcits --- Blastoderma --- Cèl·lules eucariotes --- Cèl·lules canceroses --- Cèl·lules epitelials --- Cèl·lules germinals --- Cèl·lules hepàtiques --- Cèl·lules i teixits vegetals --- Cèl·lules mare --- Cèl·lules musculars --- Cèl·lules sanguínies --- Citoplasma --- Cromatina --- Fecundació --- Fibroblasts --- Histologia --- Irritabilitat --- Mort cel·lular --- Neurones --- Neurones motores --- Patologia cel·lular --- Protoplasts --- Protozous --- Ou (Biologia) --- Ultraestructura (Biologia) --- Citologia --- Clonatge --- Embriologia --- Protoplasma --- Regeneració (Biologia) --- Ciència --- Agricultura --- Botànica --- Ciències de la salut --- Zoologia


Book
Heparanase : From Basic Research to Clinical Applications
Authors: --- ---
ISBN: 3030345211 3030345203 Year: 2020 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.

Keywords

Cancer research. --- Oncology  . --- Molecular biology. --- Cancer Research. --- Oncology. --- Molecular Medicine. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Tumors --- Cancer research --- Proteolytic enzymes --- Peptide hydrolases --- Proteases --- Hydrolases --- Physiological effect. --- Peptide Hydrolases --- Neoplasms. --- Benign Neoplasms --- Malignancy --- Malignant Neoplasms --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Benign Neoplasm --- Cancers --- Malignancies --- Malignant Neoplasm --- Neoplasias --- Neoplasm, Benign --- Neoplasm, Malignant --- Neoplasms, Malignant --- Tumor --- Medical Oncology --- Esteroproteases --- Peptidases --- Proteinases --- Proteolytic Enzymes --- Gene Products, pol --- Enzims --- Cèl·lules --- Càncer --- Carcinoma --- Carcinosi --- Càncer d'ossos --- Càncer de cap --- Càncer de coll --- Càncer de bufeta --- Càncer de fetge --- Càncer de laringe --- Càncer de mama --- Càncer de pàncrees --- Càncer de pell --- Càncer de pròstata --- Càncer de pulmó --- Càncer de ronyó --- Càncer de tiroide --- Càncer d'ovari --- Càncer gastrointestinal --- Càncer ginecològic --- Càncer en els adolescents --- Càncer en els infants --- Medicaments antineoplàstics --- Melanoma --- Leucèmia --- Sarcoma --- Carcinògens --- Cèl·lules canceroses --- Cirurgia oncològica --- Infermeria oncològica --- Malalts de càncer --- Metàstasi --- Oncologia --- Biologia --- Fisiologia --- Reproducció --- Astròcits --- Blastoderma --- Cèl·lules eucariotes --- Cèl·lules epitelials --- Cèl·lules germinals --- Cèl·lules hepàtiques --- Cèl·lules i teixits vegetals --- Cèl·lules mare --- Cèl·lules musculars --- Cèl·lules sanguínies --- Citoplasma --- Cromatina --- Fecundació --- Fibroblasts --- Histologia --- Irritabilitat --- Mort cel·lular --- Neurones --- Neurones motores --- Patologia cel·lular --- Protoplasts --- Protozous --- Ou (Biologia) --- Ultraestructura (Biologia) --- Citologia --- Clonatge --- Embriologia --- Protoplasma --- Regeneració (Biologia) --- Biocatalitzadors --- Ferments --- Catalitzadors --- Proteïnes --- Coenzims --- Enzims al·lostèrics --- Enzims microbians --- Fibrinolítics --- Hidrolases --- Iduronat-2-sulfatasa --- Inducció enzimàtica --- Isoenzims --- Malt --- Metal·loenzims --- Oxidoreductases --- Transferases --- Biocatàlisi --- Fermentació


Book
Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver
Authors: --- ---
ISBN: 3030377083 3030377075 Year: 2020 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book provides a comprehensive and up-to-date overview of the pathologic features of common benign and malignant hematopoietic disorders in spleen and liver for practicing pathologists, hematopathologists and clinicians. The authors are from large academic centers, affiliated teaching hospitals and central referral clinics and are experienced in the diagnosis of hematopoietic disorders in the spleen and liver. The book consists of 21 chapters, with the first three chapters devoted to normal histologic features, conventional, cytogenetic and molecular studies necessary for the diagnosis of hematopoietic disorders in the spleen and liver. Chapters 4 to 17 cover the primary and secondary mature B- and T/NK cell lymphomas, Hodgkin lymphoma, B and T cell lymphoblastic leukemias, myeloid neoplasms, histiocytic and dendritic neoplasms, and post-transplant disorders including post transplant lymphoproliferative disorders. Chapters 19 to 21 encompass red blood cell disorders, other benign hematologic disorders and infectious/inflammatory disorders that could mimic hematopoietic neoplasms. These chapters are formatted on specific hematopoietic neoplasms to comprise epidemiology, etiology, pathogenesis, morphology, immunophenotyping, molecular genetics, prognosis and brief treatment guidelines. Diagnostic caveats are included in order to have a quick review of the key points in each chapter. Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver covers most, if not all of the benign and malignant hematopoietic disorders in the spleen and liver and serves as a practical and useful resource for general pathologists and hematopathologists.

Keywords

Hematopoietic system. --- Hemopoietic system --- Hematopoiesis --- Hematopoietic System. --- Leukemia. --- Lymphoma. --- Neoplasms, Plasma Cell. --- Liver Diseases. --- Spleen. --- Hematopoietic Systems --- System, Hematopoietic --- Liver Dysfunction --- Disease, Liver --- Diseases, Liver --- Dysfunction, Liver --- Dysfunctions, Liver --- Liver Disease --- Liver Dysfunctions --- Plasma Cell Neoplasms --- Neoplasm, Plasma Cell --- Plasma Cell Neoplasm --- Germinoblastoma --- Lymphoma, Malignant --- Reticulolymphosarcoma --- Sarcoma, Germinoblastic --- Germinoblastic Sarcoma --- Germinoblastic Sarcomas --- Germinoblastomas --- Lymphomas --- Lymphomas, Malignant --- Malignant Lymphoma --- Malignant Lymphomas --- Reticulolymphosarcomas --- Sarcomas, Germinoblastic --- Lymphatic Diseases --- Hematologic Neoplasms --- Leucocythaemia --- Leucocythemia --- Leucocythaemias --- Leucocythemias --- Leukemias --- Myeloproliferative Disorders --- Pathology. --- Hematology. --- Oncology  . --- Oncology. --- Tumors --- Haematology --- Internal medicine --- Blood --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Malalties hematològiques --- Malalties del sistema limfàtic --- Melsa --- Fetge --- Diagnòstic. --- Oncologia --- Medicina --- Oncologia geriàtrica --- Oncologia pediàtrica --- Oncologia veterinària --- Càncer --- Infermeria oncològica --- Diagnosi --- Diagnòstic físic --- Examen mèdic (Diagnòstic) --- Exploració médica (Diagnòstic) --- Exploració clínica (Diagnòstic) --- Medicina clínica --- Cateterisme --- Cribratge --- Diagnòstic d'infermeria --- Diagnòstic diferencial --- Diagnòstic dual --- Diagnòstic molecular --- Diagnòstic prenatal --- Diagnòstic quirúrgic --- Diagnòstic per la imatge --- Electrodiagnòstic --- Entrevista clínica --- Examen físic --- Isòtops radioactius en diagnòstic mèdic --- Monitoratge de pacients --- Proves funcionals (Medicina) --- Patologia --- Pronòstic mèdic --- Símptomes --- Abdomen --- Aparell digestiu --- Tracte biliar --- Cèl·lules hepàtiques --- Bilis --- Cirurgia hepàtica --- Hepatologia --- Sistema limfàtic --- Elefantiasi --- Limfomes --- Malalties de la sang --- Malalties sanguínies --- Malalties --- Anèmia --- Eosinofília --- Mononucleosi --- Septicèmia --- Trastorns de les plaquetes sanguínies --- Hematologia

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