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Aimed at senior undergraduates and graduate students in science and biomedical engineering, this text explores the architecture of a cell's envelope and internal scaffolding, and the properties of its soft components. The book first discusses the properties of individual flexible polymers, networks and membranes, and then considers simple composite assemblages such as bacteria and synthetic cells. The analysis is performed within a consistent theoretical framework, although readers can navigate from the introductory material to results and biological applications without working through the intervening mathematics. This, together with a glossary of terms and appendices providing quick introductions to chemical nomenclature, cell structure, statistical mechanics and elasticity theory, make the text suitable for readers from a variety of subject backgrounds. Further applications and extensions are handled through problem sets at the end of each chapter and supplementary material available on the Internet.

Cells --- Physical biochemistry --- Mechanical properties --- Physical biochemistry. --- Biophysical chemistry --- Biochemistry --- Physical organic chemistry --- Cell mechanics --- Cellular mechanics --- Biomechanics --- Mechanical properties. --- Biochimie physique --- Cells - Mechanical properties

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This book is dedicated to studying the thermodynamic bases of the structure-function relationship of proteins. It moves from the elementary principles of physical chemistry to the most current topics of biochemistry, including those that may be subject to some controversy. It considers thermodynamic properties related to the stability and function of proteins from the point of view of physics in a language that, without sacrificing conceptual rigor, is easy to read. Detailing the thermodynamics of protein-ligand interactions, protein naturation, allostery, oxidative phosphorylation and protein phosphorylation, the book will be of interest to students and teachers of chemistry, physics, biochemistry and biotechnology.

Biothermodynamics. --- Bioenergetics. --- Energy Metabolism. --- Thermodynamics. --- Allosteric regulation. --- Adenosine triphosphate. --- Biochimie physique. --- Thermodynamique. --- Métabolisme énergétique. --- Bioénergétique. --- Allostérie. --- ATP. --- Ligands (biochimie) --- Fixation. --- Métabolisme énergétique. --- Bioénergétique. --- Allostérie.