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This book discusses normal brain physiology and renal physiology, as well as the interactions between the two. The physiology of the brain can easily be affected by any changes to the physiology of other systems, which in turn may compromise cerebral blood flow and oxygenation. Together the brain and the renal system help our body systems to function automatically. The book addresses the basic aspects of neurophysiology and renal physiology in three broad sections, the first of which covers the basic principles of cerebral physiology and neural regulation of the renal system. The second part reviews the normal physiology of the renal system, including the mechanism of action, while the last section summarizes the correlation between the brain and kidney. Highly informative and clearly structured, the book provides essential insights for anyone with an interest in physiology and medicine.

Neurophysiology. --- Kidneys. --- Abdomen --- Urinary organs --- Nephrology --- Nervous system --- Neurobiology --- Physiology --- Human physiology. --- Neurosciences. --- Endocrinology . --- Nephrology. --- Human Physiology. --- Endocrinology. --- Internal medicine --- Hormones --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Kidneys --- Human biology --- Human body --- Cervell --- Fisiologia --- Ronyó --- Ronyons --- Aparell urinari --- Diüresi --- Glàndules suprarenals --- Malalties del ronyó --- Nefrologia --- Biologia --- Absorció (Fisiologia) --- Adaptació (Fisiologia) --- Calor animal --- Cèl·lules --- Circulació sanguínia --- Climateri --- Composició corporal (Fisiologia) --- Creixement --- Digestió --- Electrofisiologia --- Embaràs --- Esquena --- Excitació (Fisiologia) --- Excreció --- Fisiologia animal --- Fisiologia cel·lular --- Fisiologia humana --- Lactació --- Mecànica animal --- Neurofisiologia --- Nutrició --- Òptica fisiològica --- Orientació (Fisiologia) --- Perfusió (Fisiologia) --- Psicofisiologia --- Reologia (Biologia) --- Salut --- Secreció --- Set --- Vida (Biologia) --- Anatomia --- Efectes fisiològics --- Cap --- Craniologia --- Encèfal --- Sistema nerviós central --- Bulb raquidi --- Cerebel --- Escorça cerebral --- Evolució del cervell --- Frenologia --- Hipòfisi --- Líquid cefalorraquidi --- Memòria --- Neurones motores --- Neuropsicologia --- Neuropsiquiatria --- Psicologia --- Sistema límbic --- Somnis --- Son --- Tàlem (Anatomia) --- Tronc de l'encèfal --- Cirurgia cerebral

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Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs)ïÅưusing nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance.ïÅư The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs likeïÅưDNA, siRNA, LNA, PNA, etc.

Nanomedicine. --- Nucleic acids --- Treatment.

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"The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release. In this two-part book, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers which can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies. Part II covers the following topics: Solid lipid nanoparticles and nanostructured lipid carriers; Silica based nanomaterials; Hydrogels; Metallic nanoparticles; Computational and experimental binding interactions of drug and β-cyclodextrin; Clinical milestones in nanotherapeutics; Drug delivery systems based on poly(lactide-co-glycolide) and its copolymers. The book set is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.".

Drug delivery systems. --- Nanostructured materials. --- Nanoscience --- Science

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The book highlights various aspects of management of life-threatening scenarios in obstetrics starting from the basic principles, physiology, ethics, monitoring and organization of a critical care unit. The various chapters cover management of critical illnesses involving various organ systems of the body of a pregnant woman. Furthermore, the management of a pregnant woman is unique as it involves not only management of the patient but the developing fetus in her womb as well. This book aims to help the obstetricians, postgraduate students and critical care providers with the management protocols in dealing with critically ill pregnant women.  .

Critical care medicine. --- Gynecology & Obstetrics --- Medicine --- Health & Biological Sciences --- Pregnancy --- Obstetrical emergencies. --- Complications. --- Emergencies, Obstetrical --- Emergency obstetrics --- Obstetric emergencies --- Complications of pregnancy --- High-risk pregnancy --- Pregnancy, Complications of --- Pregnant women --- Diseases --- Medical emergencies --- Obstetrics --- Obstetrical emergencies --- Obstetrics. --- Obstetrics/Perinatology/Midwifery. --- Intensive / Critical Care Medicine. --- Intensive care --- Intensive medicine --- Emergency medicine --- Intensive care units --- Maternal-fetal medicine