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There are currently no reparative therapies for severe neurological injury, including brain injury, spinal cord injury and stroke. Actually, most treatments are designed simply to limit secondary damage. However, pre-clinical data supports the idea that exogenous stem and progenitor cells have the potential to promote a reparative response to severe neurological injuries. Progenitor Cell Therapy for Neurological Injury is a compilation of seminal essays that explore many unique aspects of neurological injury, focusing on the critical translational issues of cell delivery. Specifically, it discusses routes of administration, types of progenitor cells (alone and/or in combinations), timing of delivery and adjuncts to promote cell engraftment, survival and effectiveness. In addition, many chapters address measuring the effects of transplanted cells and cell tracking. The paradigms of how cell-based therapeutics affect neurological injury is changing rapidly. The developments in this field may ultimately offer realistic hope for improvement in patients with severe injuries. This book is a vital key toward unlocking those future treatments.

Brain -- Wounds and injuries -- Treatment. --- Medicine. --- Stem cells -- Therapeutic use. --- Stem cells --- Brain --- Cell Transplantation --- Diseases --- Transplantation --- Nervous System Diseases --- Stem Cell Transplantation --- Surgical Procedures, Operative --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biology --- Health & Biological Sciences --- Cytology --- Pharmacy, Therapeutics, & Pharmacology --- Therapeutic use --- Wounds and injuries --- Treatment --- Cellular therapy. --- Nervous system --- Cell therapy --- Cells --- Therapy, Cellular --- Treatment. --- Life sciences. --- Stem cells. --- Life Sciences. --- Stem Cells. --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells

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Existing safety management methods have not had the anticipated impact of reducing accident rates at work. This is an introduction to the new behaviour based approach to safety management and quality improvement.

Industrial safety. --- Industrial safety -- Management. --- Industrial safety -- Psychological aspects. --- Psychological aspects. --- Industrial safety --- Engineering & Applied Sciences --- Technology - General --- Psychological aspects --- Management --- Management. --- Psychology, Industrial --- Industrial accidents --- Industries --- Job safety --- Occupational hazards, Prevention of --- Occupational health and safety --- Occupational safety and health --- Prevention of industrial accidents --- Prevention of occupational hazards --- Safety, Industrial --- Safety engineering --- Safety measures --- Safety of workers --- Accidents --- System safety --- Prevention

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The 4th International Symposium on Mechanobiology (ISMB) organized by the Australian Society for Mechanobiology (AuSMB) took place at the Sydney Nanoscience Hub at the University of Sydney, Australia, from the 6th to the 9th of November 2022. This conference started in 2011 with the founding of the Society in Shanghai, China, and has occurred every three years also visiting Okayama (2014) and more recently Singapore (2017). This is the first time this conference was held in Australia. The primary purpose of the 4th International Symposium on Mechanobiology (ISMB) was to act as a forum for dissemination of cutting-edge research and innovation in the field of mechanobiology. It brought together 200+ delegates from both the Australian and International communities (students, scientists, clinicians, engineers and stakeholders from academia, industry and other organisations) working in the broader field of mechanobiology to discuss new and exciting advances in the field. This collection reflects the diverse and multidisciplinary nature of mechanobiology research spanning length scales and organ systems. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Cytology. --- Biophysics. --- Cell interaction. --- Biomolecules. --- Proteins. --- Cell Biology. --- Mechanobiological Cell Signaling. --- Molecular Biophysics. --- Single-Molecule Biophysics.