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This volume presents protocols that analyze and explore gene regulatory networks (GRNs) at different levels in plants. This book is divided into two parts: Part I introduces different experimental techniques used to study genes and their regulatory interactions in plants. Part II highlights different computational approaches used for the integration of experimental data and bioinformatics-based predictions of regulatory interactions. This part of the book also provides information on essential database resources that grant access to gene-regulatory and molecular interactions in different plant genomes, with a specific focus on Arabidopsis thaliana. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Plant Gene Regulatory Networks: Methods and Protocols is a valuable resource for scientists and researchers interested in expanding their knowledge of GRNs.
Plant genetic regulation. --- Gene regulatory networks. --- Gene regulatory networks --- Réseaux de régulation génique --- Réseaux de régulation génique --- Life sciences. --- Plant science. --- Botany. --- Life Sciences. --- Plant Sciences. --- Botanical science --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Biology --- Natural history --- Plants --- Biosciences --- Sciences, Life --- Science --- Floristic botany
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Proteins --- isolation & purification --- periodicals --- Purification --- Biotechnology --- Gene Expression Regulation. --- Proteins. --- Protéines --- isolation & purification. --- Biotechnologie --- Biotechnology. --- Purification. --- Gene Expression Regulation --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- Proteids --- Molecular Mechanisms of Pharmacological Action --- RNAi Therapeutics --- Gene Regulatory Networks --- Biomolecules --- Polypeptides --- Proteomics --- periodicals. --- Protein
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DNA, Antisense --- Gene Expression Regulation --- RNA, Antisense --- Antisense nucleic acids --- Acides nucléiques antisens --- DNA, Antisense. --- Gene Expression Regulation. --- RNA, Antisense. --- Antisense nucleotides --- Nucleic acids --- Anti-Sense RNA --- Antisense RNA --- Anti Sense RNA --- RNA, Anti-Sense --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- RNAi Therapeutics --- Gene Regulatory Networks --- Anti-Sense DNA --- Antisense DNA --- Anti Sense DNA --- DNA, Anti-Sense --- Antisense nucleic acids. --- Dna, antisense. --- Gene expression regulation. --- Rna, antisense. --- Acides nucléiques antisens
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Gene expression --- Genetic regulation --- Gene Expression. --- Gene Expression Regulation. --- Gene expression. --- Genetic regulation. --- Gene regulation --- Genes --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- Expression, Gene --- Expressions, Gene --- Gene Expressions --- Gene expression regulation --- Regulation --- Expression --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- RNAi Therapeutics --- Gene Regulatory Networks --- Gene Expression Profiling --- Gene Expression --- Gene Expression Regulation --- Expression génique --- Péridiodiques. --- Régulation génétique --- Expression génique. --- Régulation génétique.
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Epigenesis --- DNA --- Epigénèse --- ADN --- Periodicals. --- Methylation --- Periodicals --- Périodiques --- Méthylation --- Cell Differentiation. --- DNA Methylation. --- Epigenesis, Genetic. --- Gene Expression Regulation. --- Epigenetica. --- Methylation. --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- Epigenetic Process --- Epigenetics Processes --- Epigenetic Processes --- Genetic Epigenesis --- Process, Epigenetic --- Processes, Epigenetic --- Processes, Epigenetics --- DNA Methylations --- Methylation, DNA --- Methylations, DNA --- Differentiation, Cell --- Cell Differentiations --- Differentiations, Cell --- Deoxyribonucleic acid --- Desoxyribonucleic acid --- Thymonucleic acid --- TNA (Nucleic acid) --- RNAi Therapeutics --- Gene Regulatory Networks --- DNA Methylation --- Methyl CpG Binding Domain --- Genomic Imprinting --- Gene Silencing --- Epigenesis, Genetic --- Embryo, Mammalian --- Gene Expression Regulation --- Cell Lineage --- Deoxyribose --- Nucleic acids --- Genes --- Embryology --- Evolution (Biology) --- Genetics --- Epigenesis. --- Life Sciences --- Zoology --- Epigenome
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Kruppel-like factors (KLFs) are attracting great attention across a wide spectrum of biological sciences and medicine because of their remarkable biological potency and the diversity of roles they play in the physiological and pathological changes of cells and tissues. This book is a comprehensive compendium of the latest research on the molecular mechanisms of KLFs, describing their roles in transcriptional regulation, cellular differentiation and development, the pathogenesis of the liver and cardiovascular systems and cancer, and generation of ES cells and iPS cells. As the only concise treatise written to date by leading experts in the field, it serves as an authoritative review of this family of molecules and is an essential reference for all who are interested in KLFs. The book also explores the potential of KLFs as targets for novel therapeutics and diagnostics, and will be invaluable in those fields.
DNA-binding proteins. --- Genetic regulation. --- Genomics. --- Medical genetics. --- Transcription factors. --- Genomics --- DNA-binding proteins --- Transcription factors --- Gene regulatory networks --- Medical genetics --- Kruppel-Like Transcription Factors --- Gene Regulatory Networks --- Physiology --- Genetics --- Zinc Fingers --- Biology --- Amino Acid Motifs --- Biological Science Disciplines --- DNA-Binding Proteins --- Regulatory Sequences, Nucleic Acid --- Transcription Factors --- Base Sequence --- Proteins --- Protein Structure, Secondary --- Natural Science Disciplines --- Disciplines and Occupations --- Protein Conformation --- Genetic Structures --- Amino Acids, Peptides, and Proteins --- Genetic Phenomena --- Molecular Conformation --- Chemicals and Drugs --- Phenomena and Processes --- Molecular Structure --- Biochemical Phenomena --- Chemical Phenomena --- Cytology --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Cells --- Cytology. --- Molecular biology. --- Growth. --- Molecular biochemistry --- Molecular biophysics --- Cell biology --- Cellular biology --- Cell growth --- Life sciences. --- Cancer research. --- Cell biology. --- Developmental biology. --- Animal genetics. --- Animal physiology. --- Life Sciences. --- Cell Biology. --- Animal Genetics and Genomics. --- Animal Physiology. --- Cancer Research. --- Developmental Biology. --- Molecular Medicine. --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cytologists --- Cell proliferation --- Oncology. --- Medicine. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Development (Biology) --- Growth --- Ontogeny --- Tumors --- Animal physiology --- Animals --- Anatomy --- Health Workforce --- Cancer research
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Gene regulatory networks play a vital role in organismal development and function by controlling gene expression. With the availability of complete genome sequences, several novel experimental and computational approaches have recently been developed which promise to significantly enhance our ability to comprehensively characterize these regulatory networks by enabling the identification of respectively their genomic or regulatory state components, or the interactions between these two in unprecedented detail. Divided into five convenient sections, Gene Regulatory Networks: Methods and Protocols details how each of these approaches contributes to a more thorough understanding of the composition and function of gene regulatory networks, while providing a comprehensive protocol on how to implement them in the laboratory. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Gene Regulatory Networks: Methods and Protocols aims to provide novices and experienced researchers alike with a comprehensive and timely toolkit to study gene regulatory networks from the point of data generation to processing, visualization, and modeling.
Gene expression --- Genetic regulation --- Genetic regulation. --- Genregulation. --- Methode. --- Netzwerk. --- Gene Regulatory Networks --- Gene Expression Regulation --- Gene Expression --- Transcription Factors --- Simulation methods. --- Genetic Processes --- Regulatory Sequences, Nucleic Acid --- Publication Formats --- Proteins --- Publication Characteristics --- Genetic Phenomena --- Base Sequence --- Amino Acids, Peptides, and Proteins --- Genetic Structures --- Phenomena and Processes --- Chemicals and Drugs --- Laboratory Manuals --- Biology --- Health & Biological Sciences --- Biophysics --- Genetics --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- Expression, Gene --- Expressions, Gene --- Gene Expressions --- Transcription Factor --- Factor, Transcription --- Factors, Transcription --- Gene Module --- Gene Circuits --- Gene Modules --- Gene Networks --- Transcriptional Networks --- Circuit, Gene --- Circuits, Gene --- Gene Circuit --- Gene Network --- Gene Regulatory Network --- Module, Gene --- Modules, Gene --- Network, Gene --- Network, Gene Regulatory --- Network, Transcriptional --- Networks, Gene --- Networks, Gene Regulatory --- Networks, Transcriptional --- Regulatory Network, Gene --- Regulatory Networks, Gene --- Transcriptional Network --- Genetic Structure --- Structure, Genetic --- Structures, Genetic --- DNA Sequences --- DNA Sequence --- Nucleotide Sequence --- RNA Sequence --- Base Sequences --- Nucleotide Sequences --- RNA Sequences --- Sequence, Base --- Sequence, DNA --- Sequence, Nucleotide --- Sequence, RNA --- Sequences, Base --- Sequences, DNA --- Sequences, Nucleotide --- Sequences, RNA --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Region, Regulatory --- Regions, Regulatory --- Regulator Regions, Nucleic Acid --- Regulatory Region --- Regulatory Regions --- Nucleic Acid Regulatory Sequences --- Regulatory Regions, Nucleic Acid (Genetics) --- Genes --- Gene expression regulation --- Gene regulation --- Expression --- Regulation --- Medicine. --- Human genetics. --- Gene expression. --- Biomedicine. --- Human Genetics. --- Gene Expression. --- Heredity, Human --- Human biology --- Physical anthropology --- Clinical sciences --- Medical profession --- Life sciences --- Medical sciences --- Pathology --- Physicians
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Developmental genetics --- Genetics. --- Developmental Biology. --- Embryology. --- Gene Expression Regulation. --- Génétique du développement --- Developmental genetics. --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- Embryologies --- Biology, Developmental --- Genetics --- Developmental Biology --- Embryology --- Gene Expression Regulation --- Developmental biology --- Growth --- RNAi Therapeutics --- Gene Regulatory Networks --- Embryonic and Fetal Development --- Growth and Development --- Genetic Structures --- Genetic Phenomena --- Auxology --- Developmental biology. --- Genetic regulation. --- Biologie du développement. --- Embryologie. --- Régulation génétique. --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Animal embryology --- Animals --- Development, Embryological --- Development, Embryonic --- Development, Zygotic --- Embryogenesis --- Embryogeny --- Embryological development --- Embryonic development --- Zoology --- Zygote development --- Zygotes --- Zygotic development --- Zygotic embryogenesis --- Morphology (Animals) --- Embryos --- Reproduction --- Development (Biology) --- Biology --- Ontogeny --- Regulation --- Development
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Genes & Development publishes high-quality research papers of broad general interest and biological significance in the areas of molecular biology, molecular genetics, and related fields. Genes & Development publishes two research formats; Research papers and short Research Communications, in addition to Review Articles and Perspectives.
Genetics --- Developmental genetics --- Cytogenetics --- Gene Expression Regulation --- Génétique --- Génétique du développement --- Cytogénétique --- Periodicals --- periodicals. --- Périodiques --- Molecular Biology --- Eukaryotic cells --- Viral genetics --- Cytogenetics. --- Gene Expression Regulation. --- Eukaryotic cells. --- Genetics. --- Viral genetics. --- Génétique du développement. --- Génétique. --- Eucaryote. --- Génétique virale. --- Cytogénétique. --- Viruses --- 575.113 <05> --- 57.017.6 <05> --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- RNAi Therapeutics --- Gene Regulatory Networks --- Cytogenetic --- Cytogenetic Analysis --- Chromosome Disorders --- Sex Chromosome Disorders --- genetics. --- Gene. Genetic apparatus. Genome--Tijdschriften --- Growth. Development. Ageing. Senescence. Death--Tijdschriften --- Genetics, biochemical --- Life Sciences --- General and Others --- Biology --- Genetics, biochemical. --- Life Sciences. --- 57.017.6 <05> Growth. Development. Ageing. Senescence. Death--Tijdschriften --- 575.113 <05> Gene. Genetic apparatus. Genome--Tijdschriften --- Génétique --- Génétique du développement --- Cytogénétique --- Périodiques --- COSPHALAPR-E EJBIOMO EPUB-ALPHA-G EPUB-PER-FT PUBMED-E --- Virus genetics --- Eucaryotic cells --- Prokaryotes --- genetics --- Microbial genetics --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Cells --- Protista --- Génétique du développement. --- Génétique. --- Génétique virale. --- Cytogénétique. --- פרוקריוטים --- תאים אאוקריוטיים --- גנטיקה --- Journal --- E-journals
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