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Discussing the systemic immune response in the contexts of health, disease, and therapy, this unique resource-the only broadly based book of its kind available on the subject-offers comprehensive examinations of the pathways and agents that affect the human immune response and provides state-of-the-art presentations on practical methods of immune modulation. Focuses on the immune response and modulation in infectious diseases, such as HIV, hepatitis, and parasitic infections and highlights immune modulating agents in gastrointestinal diseases, sepsis, cancer, and autoimmunity! Written by over 50 international authorities representing distinguished institutions in nine countries, Immune Modulating Agentsintroduces basic immunoregulatory mechanisms as homeostasis details cytokines, cellular and humoral immune responses, and hematopoiesis describes neuroendocrine - immune system interactions and the role of psychological stress on immune competence delineates factors that influence disease susceptibility, including nutrition covers drug delivery systems, gene therapy, organ transplantation, arthritis treatment, and vaccination strategies shows how to design clinical trials using immune modulating agents and more!
Immune response --- Biological response modifiers. --- Regulation. --- Biomolecules --- Cancer --- Cellular control mechanisms --- Immunopharmacology --- Biological response modulators --- Biomodulators --- BRMs (Biochemistry) --- Immunomodulators --- Immunoregulators --- Modifiers, Biological response --- Modulators, Biological response --- Idiotypic networks --- Biological response modifiers --- Ir genes --- Immune modulation --- Immunity --- Immunomodulation --- Immunoregulation --- Regulation of immunity --- Regulation of the immune response --- Immunotherapy --- Regulation
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Neuroimmunology --- Neuro-immunologie --- Neuroimmunology. --- Neuro-immunologie. --- Immune System --- Nervous System --- Neuroimmunomodulation. --- physiology. --- immunology. --- Neuroimmune Mechanisms --- Neuroimmune Process --- Neuroimmune Processes --- Mechanism, Neuroimmune --- Mechanisms, Neuroimmune --- Neuroimmune Mechanism --- Process, Neuroimmune --- Neuroimmunomodulation --- Homeostasis --- Neurosecretory Systems --- Psychoneuroimmunology --- Neurogenic Inflammation --- Immunology --- Neurosciences --- physiology --- immunology --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Immune Systems --- System, Immune --- Systems, Immune --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction
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Neuroimmunology --- Neuroimmunomodulation --- Neuroimmunomodulation. --- Neuroimmunology. --- Neuroimmunologie. --- Zeitschrift. --- Online-Publikation. --- Immunology --- Neurosciences --- Neuroimmune Mechanisms --- Neuroimmune Process --- Neuroimmune Processes --- Mechanism, Neuroimmune --- Mechanisms, Neuroimmune --- Neuroimmune Mechanism --- Process, Neuroimmune --- Homeostasis --- Neurosecretory Systems --- Psychoneuroimmunology --- Neurogenic Inflammation --- Neuroimmunologie --- Zeitschrift --- Online-Ressource --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction --- Netzpublikation --- Online-Publikation --- Computerdatei im Fernzugriff --- Online-Dokument --- On-line-Dokument --- On-line-Publikation --- Elektronische Publikation --- Periodikum --- Zeitschriften --- Presse --- Fortlaufendes Sammelwerk --- Immunoneurologie --- Immunologie --- Neurologie
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Psychoneuroimmunology --- Neuroimmunology --- Neuroimmunology. --- Psychoneuroimmunology. --- Neuroimmunomodulation. --- Psychoimmunology --- Psychoneuroimmunoendocrinology --- Neuroimmunomodulation --- Immunology --- Neurosciences --- Neuroimmune Mechanisms --- Neuroimmune Process --- Cholinergic Anti-inflammatory Pathway --- Neuro-immune Axis --- Neuro-immune Communication --- Neuro-immune Interactions --- Neuro-immunomodulation --- Neuroimmune Axis --- Neuroimmune Communication --- Neuroimmune Interactions --- Neuroimmune Processes --- Vagal Anti-inflammatory Pathway --- Vagal-immune Interactions --- Anti-inflammatory Pathway, Cholinergic --- Anti-inflammatory Pathway, Vagal --- Cholinergic Anti inflammatory Pathway --- Cholinergic Anti-inflammatory Pathways --- Communication, Neuro-immune --- Communication, Neuroimmune --- Interaction, Neuro-immune --- Interaction, Neuroimmune --- Mechanism, Neuroimmune --- Neuro immune Axis --- Neuro immune Communication --- Neuro immune Interactions --- Neuro immunomodulation --- Neuro-immune Communications --- Neuro-immune Interaction --- Neuroimmune Communications --- Neuroimmune Interaction --- Neuroimmune Mechanism --- Process, Neuroimmune --- Vagal Anti inflammatory Pathway --- Vagal Anti-inflammatory Pathways --- Vagal immune Interactions --- Vagal-immune Interaction --- Homeostasis --- Neurosecretory Systems --- Neurogenic Inflammation --- cognition --- perception --- emotion --- personality --- psychoneuroimmunology
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Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments. The authors explain in each chapter the scientific basis behind such therapeutic agents as monoclonal antibodies, cytokines, vaccines, and T-cells, and illustrate their clinical manipulation to combat cancer. Additional chapters address statistical analysis-both of clinical trials and assay evaluations-methods for the discovery of antigens, adoptive T cell therapy, and adaptive and innate immunity. The challenges in clinical trial design, the need for biomarkers of response-such as novel imaging techniques and immunologic monitoring-and the new advances and directions in cancer immunotherapy are also fully examined.
Neoplasms. --- Antineoplastic Agents. --- Immunotherapy. --- Cancer --- Antineoplastic agents --- Anticancéreux --- Design. --- Immunothérapie --- Conception --- Antineoplastic agents -- Design. --- Cancer -- Immunotherapy. --- Neoplasms -- immunology. --- Neoplasms -- therapy. --- Neoplasms --- Immunotherapy --- Immunomodulation --- Diseases --- Biological Therapy --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Oncology --- Medicine --- Health & Biological Sciences --- Design --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Medicine. --- Cancer research. --- Biomedicine. --- Cancer Research. --- Drugs --- Chemotherapy --- Immunological aspects --- Treatment --- immunology. --- therapy.
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Cancer has surpassed heart disease as the number one killer in the world, and standard cancer therapy such as radiation, chemotherapy, and surgery may have reached its plateau in further improving the outcome of treated patients. Biological therapies combined with other treatment approaches may be the next X-factor to greatly extend survival time and improve patients’ quality of life. One of the most developed fields in biological therapy is immune therapy, which has stemmed into many branches due to its significance and the tremendous effort by a large population of scientists. Tumor-targeted antibody therapy has been successfully used for treating some types of tumors, and the first tumor vaccine against ovarian cancer has been developed for clinical application. Targeted Cancer Immune Therapy provides comprehensive coverage of novel immune therapeutic approaches, including cytokine therapy, engineered cell therapy, and the application of tumor-targeted antibodies for generating tumor-specific cell therapy, TLR ligand therapy, and cytokine therapy. In the section "Cytokine Immune Therapy," the authors review relatively new cytokine family members, such as the IL12 family, IL18, IL21, IL24, IL28, and IL29, in regard to the anti-tumor function and application in treating tumors. The strategy for targeting and retaining cytokines in the tumor microenvironment is also reviewed. The section "Cell-based Immune Therapy" focuses on reviewing "state of the art" approaches for engineering potent immune regulatory or effector cells, such as dendritic cells, T cells, and stem cells, for tumor targeting and initiation of tumor specific immune response. In the section "Targeted Immune Therapy," the authors rearticulate antibody therapy for boosting immune response, which includes immunocytokines, "T-body," and tumor targeted CpG ODN. Some or all of these innovative approaches may ultimately become effective future immune therapies for treating malignancy.
Cancer -- Immunotherapy. --- Cancer. --- Tumors -- Immunological aspects. --- Cancer --- Immunotherapy --- Methods --- Neoplasms --- Investigative Techniques --- Immunomodulation --- Diseases --- Biological Therapy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Therapeutics --- Oncology --- Internal Medicine --- Medicine --- Health & Biological Sciences --- Immunotherapy. --- Treatment. --- Cancer therapy --- Cancer treatment --- Therapy --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Physiological effect --- Immunological aspects --- Treatment --- Oncology. --- Toxicology. --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Toxicology
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Mycophenolic acid --- Transplantation of organs, tissues, etc --- Immunotherapy --- Immunologic Factors --- Therapeutics --- Host vs Graft Reaction --- Investigative Techniques --- Fatty Acids --- Caproates --- Transplantation --- Immunologic Techniques --- Acids, Acyclic --- Transplantation Immunology --- Physiological Effects of Drugs --- Diagnostic Techniques and Procedures. --- Surgical Procedures, Operative --- Immunomodulation --- Lipids --- Pharmacologic Actions --- Biological Therapy --- Carboxylic Acids --- Organic Chemicals --- Immune System Phenomena --- Chemical Actions and Uses --- Mycophenolic Acid --- Immunosuppression Therapy --- Immunosuppressive Agents --- Organ Transplantation --- Graft Rejection --- Methods --- Drug Therapy --- Complications
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This comprehensive volume assembles the insights and experience of over twenty experts and thought leaders in the field of autoimmune disease and immunotherapy. These discussions represent some of the newest concepts in autoimmune mechanisms and an array of new treatments that would have been considered science fiction only two decades ago. This book provides a wide-ranging review of two main arenas of current research: that of autoimmune mechanisms of disease and that of the latest developments in immunotherapy, with an emphasis upon multiple sclerosis. The conclusions reached by these authors will influence our thinking about autoimmune disease mechanisms and our methods of patient treatment in one of the fastest developing areas of modern medicine. Immune Regulation and Immunotherapy in Autoimmune Disease is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of immunology, microbiology, infectious disease, virology, pharmacology, and medicine.
Autoimmune diseases --- Immune response --- Immunotherapy. --- Regulation. --- Immune modulation --- Immunity --- Immunomodulation --- Immunoregulation --- Regulation of immunity --- Regulation of the immune response --- Idiotypic networks --- Biological response modifiers --- Ir genes --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Regulation --- Immunology. --- Microbiology. --- Emerging infectious diseases. --- Medical virology. --- Toxicology. --- Infectious Diseases. --- Virology. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Medical microbiology --- Virology --- Virus diseases --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Toxicology --- Infectious diseases. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Microbiology --- Physiological effect
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Heat Shock Proteins: Potent Mediators of Inflammation and Immunity currently provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulates the hosts immune response. Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step wise fashion takes the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provides answers as to its biological significance to the host. From the early stages of binding and receptors-mediated signalling, to new paradigms by which heat shock proteins are released into the circulation, to antigen processing and presentation, and finally to the immune response itself this book is a must read for graduate and postgraduates in the field of Biology (plant and mammal), Biochemistry (pro- and eukaryotic), Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology.
Heat shock proteins. --- Immune response --- Regulation. --- Medicine. --- Cancer research. --- Immunology. --- Laboratory medicine. --- Molecular biology. --- Biomedicine. --- Molecular Medicine. --- Cancer Research. --- Laboratory Medicine. --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Diagnosis --- Pathology --- Immunobiology --- Life sciences --- Serology --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Physicians --- Immune modulation --- Immunity --- Immunomodulation --- Immunoregulation --- Regulation of immunity --- Regulation of the immune response --- Idiotypic networks --- Biological response modifiers --- Ir genes --- Stress proteins --- Proteins --- Regulation --- Oncology. --- Medical laboratories. --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Tumors --- Health Workforce
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Hemic and Immune Systems --- Immune System Phenomena --- Immunomodulation --- Phenomena and Processes --- Anatomy --- Biological Therapy --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Immunity --- Immunotherapy --- Immune System --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Immunology. Immunopathology --- immunologie --- antigenen --- geneeskunde --- fysiologie --- allergieën --- 615.37 --- 577.27 --- 612.017 --- Immunology --- 612.017 Immunity. Adaptation. Toxins. Antitoxins --- Immunity. Adaptation. Toxins. Antitoxins --- 577.27 Molecular bases of immunity. Molecular immunology --- Molecular bases of immunity. Molecular immunology --- 615.37 Immunotherapy --- Immunotherapies --- Combined Antibody Therapeutics --- Immunity, Active --- Immunologic Techniques --- physiology --- physiopathology --- Immune System Diseases. --- Immune System. --- Immune system --- Immunité --- Système immunitaire --- Immunothérapie --- Immunologie --- Physiology --- Physiologie --- Immune System Diseases
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