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Book
Natural functions
Authors: --- ---
ISBN: 3764374993 3764374985 Year: 2007 Publisher: Basel : London : Birkhauser ; Springer [distributor],

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Abstract

The Carotenoids book series provides detailed accounts of the fundamental chemistry of carotenoids and the basic methods used in carotenoid research, and critical discussions of the biochemistry, functions and applications of these important compounds. Volume 4 and its companion, Volume 5, deal with the functions of carotenoids in all kinds of living organisms and the actions of carotenoids in human nutrition and health. The material presented in the earlier Volumes is all relevant to studies of biological functions and actions. In particular, biological studies must be supported by a rigorous analytical base. The various analytical procedures described in Volumes 1A and 1B, supplemented by the data for individual compounds given in the Carotenoids Handbook, must be understood and applied correctly, whether they are being used for quantitative analysis, identification or in complex studies of carotenoids in situ. In the first part of Volume 4, the structural features that are most important for determining the properties and hence the biological roles of carotenoids are emphasized. The overall molecular geometry (size, three-dimensional shape, presence of functional groups) is vital to ensure that the carotenoid fits into cellular, sub-cellular and molecular structures in the correct location and orientation to allow it to function efficiently. Specific interactions with other molecules, e.g. to form aggregates or complexes with proteins, strongly influence the properties of a carotenoid in vivo and are thus also crucial to functioning. The extended delocalized p-electron system that characterizes the central part of the structure gives the carotenoids their peculiar photochemical properties and reactivity towards oxidizing agents and free radicals. This treatment provides a foundation for the description of the main functions of carotenoids and their breakdown products in the second part of Volume 4 and in Volume 5. Topics covered in Volume 4 include various aspects of the roles of carotenoids in colour and colouration, photosynthesis and other photofunctions, and protection. The formation and roles of carotenoid metabolites and breakdown products as perfume/aroma compounds and as vitamin A are also outlined; the latter is dealt with in more detail in Volume 5, which provides a comprehensive discussion of carotenoids in human health and nutrition.. Biologists now are not only discovering new phenomena but are striving to elucidate details of the underlying mechanisms that explain their observations. Chemistry is moving in new directions relevant to studies in vivo and new techniques are being developed to investigate structural details and interactions and to detect and interpret changes on an ever shorter timescale. Volumes 4 and 5 thus point the way to the future of carotenoid research by highlighting the importance of interdisciplinary approaches to study these complex and sophisticated systems.


Book
Carotenoids.
Authors: --- ---
ISBN: 3764375000 9786612825774 3764375019 1282825771 Year: 2009 Publisher: Basel ; Boston : Birkhauser Verlag,

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Abstract

More than twenty years after the idea of this Carotenoids book series was first discussed, we finally reach the end of the project with Volume 5, which covers the functions and actions of carotenoids in human nutrition and health. In 1971, in Isler’s book Carotenoids, functions of carotenoids and vitamin A were covered in just two chapters. Now, thanks to technical developments and multidisciplinary approaches that make it possible to study functional processes in great detail, this subject is the most rapidly expanding area of carotenoid research, and occupies two full volumes, Volumes 4: Natural Functions and 5: Nutrition and Health. Although Volume 5 can be used as a single stand-alone volume, the two were planned as companion volumes to be used together. To understand the mechanisms of functions and actions of carotenoids, including how carotenoids may be involved in maintaining human health, requires understanding of the underlying principles, which are presented in the first part of Volume 4. The general philosophy and strategy of the series, to have expert authors review and analyse critically a particular topic and present information and give guidance on practical strategies and procedures is maintained in Volumes 4 and 5. It is also the aim that these publications should be useful for both experienced carotenoid researchers and newcomers to the field.

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