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Immunology. Immunopathology --- Molecular biology --- DNA vaccines --- Gene therapy --- Vaccins à l'ADN --- Thérapie génique --- Periodicals. --- Périodiques --- Vaccines, DNA. --- Gene Therapy. --- DNA vaccines. --- Gene therapy. --- Genetic Therapy. --- DNA Therapy --- Gene Therapy, Somatic --- Genetic Therapy, Gametic --- Genetic Therapy, Somatic --- Therapy, DNA --- Therapy, Gene --- Therapy, Somatic Gene --- Gene Therapy --- Somatic Gene Therapy --- Gametic Genetic Therapies --- Gametic Genetic Therapy --- Genetic Therapies --- Genetic Therapies, Gametic --- Genetic Therapies, Somatic --- Somatic Genetic Therapies --- Somatic Genetic Therapy --- Therapies, Gametic Genetic --- Therapies, Genetic --- Therapies, Somatic Genetic --- Therapy, Gametic Genetic --- Therapy, Genetic --- Therapy, Somatic Genetic --- Genetic vaccines --- DNA Vaccines --- Naked DNA Vaccines --- Nucleic Acid Vaccines --- Polynucleotide Vaccines --- Recombinant DNA Vaccines --- Vaccines, Recombinant DNA --- DNA Vaccines, Naked --- DNA Vaccines, Recombinant --- Vaccines, Naked DNA --- Vaccines, Nucleic Acid --- Vaccines, Polynucleotide --- Gene Transfer Techniques --- Genetic Services --- Genes, Transgenic, Suicide --- Genetic engineering --- Therapeutics --- Vaccines --- moleculaire biologie --- Microbiology & Immunology --- vaccinatie --- DNA Vaccine --- Naked DNA Vaccine --- Nucleic Acid Vaccine --- Polynucleotide Vaccine --- Recombinant DNA Vaccine --- Acid Vaccine, Nucleic --- DNA Vaccine, Naked --- DNA Vaccine, Recombinant --- Vaccine, DNA --- Vaccine, Naked DNA --- Vaccine, Nucleic Acid --- Vaccine, Polynucleotide --- Vaccine, Recombinant DNA --- Teràpia genètica. --- Vacunes. --- Vaccins à ADN --- Vaccins à ADN. --- Thérapie génique.
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In DNA Vaccines: Methods and Protocols, state-of-the-art review articles by leading experts summarize how to develop and employ the highly promising new DNA vaccines, what clinical results can be expected from their use, and what is known about how they work. Key topics range from vaccine design and construction to preparation and delivery methods, including the use of classical adjuvants, "genetic adjuvants," and the immunostimulatory properties of DNA and selected oligonucleotide sequences. Several contributors provide strategic ideas on antigen engineering and describe the particularly novel applications of DNA vaccine methodology that have recently emerged. In addition, there is a discussion of dendritic cells and antigen-presenting cells, the understanding of whose actions holds great promise for modulating the immune response, and thus for treating disease. Cutting-edge and comprehensive, DNA Vaccines: Methods and Protocols provides a broad panorama of the methods and thinking from which the vaccines of tomorrow will evolve, and so constitutes an invaluable sourcebook for both experts developing new applications and newcomers who want to gain mastery of the techniques and problems involved.
DNA vaccines --- Research --- Methodology --- Vaccines, Synthetic --- Methods --- Science --- Antigens --- Vaccines --- Investigative Techniques --- Recombinant Proteins --- Biological Factors --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Products --- Natural Science Disciplines --- Proteins --- Chemicals and Drugs --- Complex Mixtures --- Amino Acids, Peptides, and Proteins --- Disciplines and Occupations --- Vaccines, DNA --- Research Design --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Medical sciences. --- Molecular biology --- Methodology. --- Genetic vaccines --- Basic medical sciences --- Basic sciences, Medical --- Biomedical sciences --- Health sciences --- Preclinical sciences --- Sciences, Medical --- Life sciences --- Medicine --- Research&delete& --- Pharmacy. --- Chemistry --- Drugs --- Materia medica --- Pharmacology --- DNA vaccines - Research - Methodology
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In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s.
DNA vaccines --- 57.083.3 --- 615.375 --- Genetic vaccines --- Vaccines --- 57.083.3 Immunological methods and techniques --- Immunological methods and techniques --- 615.375 Other immunizing agents. Gene therapy --- Other immunizing agents. Gene therapy --- Research&delete& --- Methodology --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Research
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Avian influenza --- DNA vaccines --- DNA vaccines. --- Vaccination --- United States. --- Genetic vaccines --- Vaccines --- Avian flu --- Bird flu --- Fowl pest --- Fowl plague --- Influenza in birds --- Birds --- Influenza --- Poultry --- Virus diseases --- ABŞ --- ABSh --- Ameerika Ühendriigid --- America (Republic) --- Amerika Birlăshmish Shtatlary --- Amerika Birlăşmi Ştatları --- Amerika Birlăşmiş Ştatları --- Amerika ka Kelenyalen Jamanaw --- Amerika Qūrama Shtattary --- Amerika Qŭshma Shtatlari --- Amerika Qushma Shtattary --- Amerika (Republic) --- Amerikai Egyesült Államok --- Amerikanʹ Veĭtʹsėndi͡avks Shtattnė --- Amerikări Pĕrleshu̇llĕ Shtatsem --- Amerikas Forenede Stater --- Amerikayi Miatsʻyal Nahangner --- Ameriketako Estatu Batuak --- Amirika Carékat --- AQSh --- Ar. ha-B. --- Arhab --- Artsot ha-Berit --- Artzois Ha'bris --- Bí-kok --- Ē.P.A. --- É.-U. --- EE.UU. --- Egyesült Államok --- ĒPA --- Estados Unidos --- Estados Unidos da América do Norte --- Estados Unidos de América --- Estaos Xuníos --- Estaos Xuníos d'América --- Estatos Unitos --- Estatos Unitos d'America --- Estats Units d'Amèrica --- Ètats-Unis d'Amèrica --- États-Unis d'Amérique --- ÉU --- Fareyniḳṭe Shṭaṭn --- Feriene Steaten --- Feriene Steaten fan Amearika --- Forente stater --- FS --- Hēnomenai Politeiai Amerikēs --- Hēnōmenes Politeies tēs Amerikēs --- Hiwsisayin Amerikayi Miatsʻeal Tērutʻiwnkʻ --- Istadus Unidus --- Jungtinės Amerikos valstybės --- Mei guo --- Mei-kuo --- Meiguo --- Mî-koet --- Miatsʻyal Nahangner --- Miguk --- Na Stàitean Aonaichte --- NSA --- S.U.A. --- SAD --- Saharat ʻAmērikā --- SASht --- Severo-Amerikanskie Shtaty --- Severo-Amerikanskie Soedinennye Shtaty --- Si͡evero-Amerikanskīe Soedinennye Shtaty --- Sjedinjene Američke Države --- Soedinennye Shtaty Ameriki --- Soedinennye Shtaty Severnoĭ Ameriki --- Soedinennye Shtaty Si͡evernoĭ Ameriki --- Spojené obce severoamerické --- Spojené staty americké --- SShA --- Stadoù-Unanet Amerika --- Stáit Aontaithe Mheiriceá --- Stany Zjednoczone --- Stati Uniti --- Stati Uniti d'America --- Stâts Unîts --- Stâts Unîts di Americhe --- Steatyn Unnaneysit --- Steatyn Unnaneysit America --- SUA --- Sŭedineni amerikanski shtati --- Sŭedinenite shtati --- Tetã peteĩ reko Amérikagua --- U.S. --- U.S.A. --- United States of America --- Unol Daleithiau --- Unol Daleithiau America --- Unuiĝintaj Ŝtatoj de Ameriko --- US --- USA --- Usono --- Vaeinigte Staatn --- Vaeinigte Staatn vo Amerika --- Vereinigte Staaten --- Vereinigte Staaten von Amerika --- Verenigde State van Amerika --- Verenigde Staten --- VS --- VSA --- Wááshindoon Bikéyah Ałhidadiidzooígíí --- Wilāyāt al-Muttaḥidah --- Wilāyāt al-Muttaḥidah al-Amirīkīyah --- Wilāyāt al-Muttaḥidah al-Amrīkīyah --- Yhdysvallat --- Yunaeted Stet --- Yunaeted Stet blong Amerika --- ZDA --- Združene države Amerike --- Zʹi͡ednani Derz͡havy Ameryky --- Zjadnośone staty Ameriki --- Zluchanyi͡a Shtaty Ameryki --- Zlucheni Derz͡havy --- ZSA
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