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ISBN: 0896036103 0896036154 9786610821037 1280821035 1592591361 9786610821693 1280821698 159259137X 9780896036154 9780896036109 Year: 2001 Volume: 57 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,
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Although ninety percent of fatal cancer cases involve the spread of a primary tumor, the formation of metastases is still a poorly understood, complex process and a significant problem in the treatment of cancer patients. In Metastasis Research Protocols, leading international investigators describe the key methods needed to investigate why and how metastasis occurs. Volume I of this two-volume set, Analysis of Cells and Tissues, presents a comprehensive collection of established and leading-edge techniques for analyzing the expression of key molecules and for examining their production at the genetic level. The work focuses on the analysis and mapping of molecules produced by cells and tissues, and on the molecular biology underlying their expression. The traditional methods range from the histopathological and the immunocytochemical to SDS-PAGE, Western blotting, and enzyme zymography. Newer and more specialized techniques for analyzing the genetic aspects of metastasis include in situ hybridization to localize mRNAs, FISH, CGH, methylation analysis of CpG islands, RT-PCR, and differential display. The second volume of this set, Analysis of Cell Behavior In Vitro and In Vivo, moves to the level of living cells and tissues to present methodologies applicable to examining metastatic behavior in vitro and in the whole animal. Comprehensive and authoritative, the two volumes of Metastasis Research Protocols constitute a gold-standard collection of readily reproducible methods for understanding the metastatic cascade-first at the cellular and molecular levels, then at the level of the whole organism-responsible for the spread of cancer and for developing novel strategies to combat its spread.
Metastasis --- Cancer cells --- Cytology --- Neoplasm Metastasis --- Cancer cells -- Laboratory manuals. --- Cytology -- Laboratory manuals. --- Electronic books. -- local. --- Metastasis -- Laboratory manuals. --- Neoplastic Processes --- Clinical Laboratory Techniques --- Investigative Techniques --- Neoplasms --- Pathologic Processes --- Cell Transformation, Neoplastic --- Cytological Techniques --- Pathological Conditions, Signs and Symptoms --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Health & Biological Sciences --- Oncology --- Cells --- Pathology, Cellular --- Cancer --- Cancer metastasis --- Dissemination of cancer --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Dissemination --- Oncology . --- Oncology. --- Tumors --- Metastasis - Laboratory manuals --- Cancer cells - Laboratory manuals --- Cytology - Laboratory manuals --- Neoplasm Metastasis - laboratory manuals --- Cytology - laboratory manuals
ISBN: 0444801995 0444802487 9780444802484 9780444801999 Year: 1980 Volume: v. 8 Publisher: Amsterdam Elsevier
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Cell culture --- Cytology --- Cells, Cultured --- Tissue Culture Techniques --- Culture Technique, Tissue --- Culture Techniques, Tissue --- Tissue Culture Technique --- Cultured Cells --- Cell, Cultured --- Cultured Cell --- Organ Culture Techniques --- Coculture Techniques --- Cell Culture Techniques --- Culture Techniques --- Human Umbilical Vein Endothelial Cells --- Cultures (Biology) --- Laboratory manuals --- Technique --- Biological techniques --- General embryology. Developmental biology --- Cell culture. --- Cells, Cultured. --- Tissue culture. --- Laboratory manuals. --- Clinical Laboratory Techniques --- Cells --- Investigative Techniques --- Anatomy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Monograph --- Anatomies --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Cell --- Cell Biology --- Clinical Laboratory Diagnoses --- Clinical Laboratory Testings --- Clinical Laboratory Tests --- Diagnoses and Laboratory Examinations --- Diagnosis, Laboratory --- Laboratory Diagnosis --- Laboratory Examinations and Diagnoses --- Laboratory Techniques, Clinical --- Clinical Laboratory Technique --- Clinical Laboratory Test --- Clinical Laboratory Testing --- Diagnose, Clinical Laboratory --- Laboratory Diagnoses --- Laboratory Technique, Clinical --- Laboratory Test, Clinical --- Laboratory Testing, Clinical --- Technique, Clinical Laboratory --- Test, Clinical Laboratory --- Testing, Clinical Laboratory --- Laboratories --- Medical Laboratory Science --- Clinical Laboratory Services --- Culture Technique --- Technique, Culture --- Techniques, Culture --- Diffusion Chambers, Culture --- Cytology - Laboratory manuals
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