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This volume looks at major clinical trials for motor and non-motor symptoms in Parkinson’s Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection. Chapters in this book discuss topics such as toxin-based rodent or genetic models of PD; clinical trials for motor symptoms, L-DOPA related motor complications, and gait disorders; clinical trials for mood disorders, troubled sleep, autonomic dysfunction; and clinical trials for disease modifying therapies. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory or research center. Cutting-edge and authoritative, Clinical Trials in Parkinson’s Disease is a valuable resource for clinicians and researchers who want to enhance their interpretation of results from clinical trials and to design their own high-quality trials. .
Malaltia de Parkinson --- Assaigs clínics --- Assaigs terapèutics --- Estudis clínics --- Estudis terapèutics --- Experimentació humana en medicina --- Paràlisi agitant --- Malalties cerebrals --- Malalties neurodegeneratives --- Neurosciences. --- Neuroscience. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system
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This volume explores current viewpoints and knowledge gaps in the field of traumatic brain injury (TBI). The chapters in this book cover topics ranging from development of in vitro and animal TBI models, to diagnostic imaging and disease monitoring in patients. Designing pre-clinical and clinical trials is also discussed. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Practical and thorough, Pre-Clinical and Clinical Methods in Brain Trauma Research is a valuable resource for both scientists and clinical researchers interested in learning about important techniques and their applications in the field of TBI.
Neurosciences. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Lesions cerebrals --- Assaigs clínics --- Investigació mèdica --- Manuals de laboratori --- Tècniques de laboratori --- Investigació biomèdica --- Investigació --- Investigació farmacèutica --- Experimentació humana en medicina --- Ressenyes sistemàtiques (Investigació mèdica) --- Animals de laboratori --- Assaigs terapèutics --- Estudis clínics --- Estudis terapèutics --- Dany cerebral --- Danys cerebrals --- Disfuncions cerebrals --- Lesió cerebral --- Malalties cerebrals --- Psicopatologia --- Encefalopatia hepàtica --- Estat vegetatiu persistent --- Paràlisi cerebral --- Pacients amb lesions cerebrals
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