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ISBN: 0323527302 0323527299 9780323527309 9780323527293 Year: 2017 Publisher: Kidlington, [England] : William Andrew,
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Liposomes. --- Nanostructures. --- Nanoscience --- Physics --- Phospholipid vesicles --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids
ISBN: 9780444829177 0444829172 9780080536088 0080536085 1281019216 9781281019219 9786611019211 Year: 1998 Publisher: Amsterdam ; New York : Elsevier,
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The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 1960's by A.D. Bangham. While academic research of liposomes as a model membrane system has always flourished, as the exponential growth of papers can testify, the application of these findings to medically useful products has gone through several crises. Following the original optimism in the 70's and early 80's, a period of severe skepticism ensued at the end of the 80's and beginning of the 90's, culminating in a moderate but real optimism in the mid 90's, as a result of a successful lau
Liposomes --- Drug carriers (Pharmacy) --- Drug targeting. --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Target organs (Anatomy) --- Carriers, Drug (Pharmacy) --- Drug carrier systems (Pharmacy) --- Drug vehicles (Pharmacy) --- Vehicles, Drug (Pharmacy) --- Drug delivery systems --- Phospholipid vesicles --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Therapeutic use. --- Targeting --- Dosage forms --- Carriers --- Vehicles --- Drug carriers --- Drug targeting --- Therapeutic use
ISBN: 1281050431 9786611050436 0080479774 0123584655 Year: 1999 Publisher: San Diego, CA : Academic Press,
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Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of ""healthy genes"" into patients' cells. The problem, however, was that viral vectors proved unnecessarily harmful to humans: subjects experienced inflammatory activity and negative immunological responses to the genes. Viral vectors were also unable to meet the needs of the pharmaceutical community: they were not reproducible in large-scale proportions in cost-effective ways.
DNA-ligand interactions. --- Drug targeting. --- Gene therapy. --- Gene therapy. Genetic vectors. DNA-ligand interactions. Liposomes. Drug targeting. --- Genetic transformation. --- Genetic vectors. --- Liposomes. --- Recombination, Genetic --- Genetic Structures --- Genetic Techniques --- Investigative Techniques --- Genetic Phenomena --- Genetic Processes --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Genetic Vectors --- Gene Transfer Techniques --- Transformation, Genetic --- Medicine --- Health & Biological Sciences --- Pathology --- Gene transfer --- Transformation (Genetics) --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Phospholipid vesicles --- Binding, DNA-ligand --- DNA-ligand binding --- Interactions, DNA-ligand --- Therapy, Gene --- Cloning vectors --- Expression vectors (Genetics) --- rDNA vectors --- Recombinant DNA vectors --- Vectors, Genetic --- Targeting --- Genetic recombination --- Microbial genetics --- Nucleic acids --- Transfection --- Target organs (Anatomy) --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Ligand binding (Biochemistry) --- Genetic engineering --- Therapeutics --- Gene expression --- Molecular cloning --- Recombinant DNA --- Dosage forms
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